ISSN:
1749-6632
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Natural Sciences in General
Notes:
1. The metabolic effects of human growth hormone were studied in six patients who sustained moderate to severe burns averaging 30% of the body surface area.2. Two normal controls were also studied.3. The patients and the controls were placed on a constant intake of 9.0 gm of nitrogen/m2 of body surface and 1500 cal/m2 and complete balance studies of nitrogen, potassium, sodium and chloride were carried out for 16 days.4. When growth hormone was given, increased storage of nitrogen, potassium, sodium and chloride and weight gain occurred, but with marked variability from patient to patient and even in the same patient at various times post-burn.5. The administration of growth hormone was associated with an increase in oxygen utilization which, however, did not show a quantitative relationship with the degree of nitrogen storage.6. Fat mobilization was indicated by a sustained increase in serum nonesterified fatty acid levels with growth hormone administration.7. The most striking nitrogen retention occurred in the early anabolic phase and not during the height of the catabolic phase.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1749-6632.1968.tb14722.x
