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Intrinsic insensitivity to cadmium of the l-lactate oxidizing system in Staphylococcoccus aureus (1995)

Tynecka, Zofia ; Malm, Anna

Oxford, UK : Blackwell Publishing Ltd

FEMS microbiology letters 129 (1995), S. 0

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ISSN: 1574-6968

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology

Notes: Abstract Starved cells of cadmium-sensitive Staphylococcus aureus 17810S accumulated 109Cd via the Mn2+ porter energized by the membrane potential (ΔΨ) generated by l-lactate oxidation. However, Cd2+ accumulation did not result in inhibition of respiration and consequent generation of electrochemical proton gradient (ΔμH+) via the respiratory chain. Thus, ΔμH+-consuming processes, such as ATP synthesis and [14C]glutamate transport proceeded normally, despite the presence of Cd2+ in the cytoplasm. The mechanism of the intrinsic cadmium-insensitivity of the l-lactate oxidizing system is discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1574-6968.1995.tb07549.x

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