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Regulation of the yeast vacuolar aminopeptidase Y gene (APY1) expression (1996)

Herrera-Camacho, Irma ; Suárez-Rendueles, Paz

Oxford, UK : Blackwell Publishing Ltd

FEMS microbiology letters 139 (1996), S. 0

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ISSN: 1574-6968

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology

Notes: Abstract The steady-state levels of the aminopeptidase Y (APY1) transcript and the levels of assayable aminopeptidase Y activity were measured under a variety of nutritional conditions. Specific APY1 mRNA is less abundant in cells grown in minimal medium than in cells grown in rich medium, while active enzyme levels follow just the opposite pattern. Aminopeptidase Y activity decreases when cells are deprived of glucose without a concomitant fall in mRNA levels. Production of aminopeptidase Y is not markedly affected by nitrogen regulation. APY1 gene expression is not disturbed in heat-shocked cells. Our data support the idea that the main control event in vacuolar aminopeptidase Y expression is a post-transcriptional step.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1574-6968.1996.tb08191.x

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