ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Inversion 16 (Inv(16)) results in a fusion between genes CBFB on the q arm and MYH11 on the p arm and is associated with acute myeloid leukemia (AML) subtype M4Eo. CBFB encodes a protein (CBFb) that forms a heterodimeric transcription factor with RUNX1/AML1, which itself is disrupted by several ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/86966