ISSN:
1399-0047
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
Staphylokinase, a 17 kDa protein, produced by certain strains of Staphylococcus aureus functions as a fibrin-specific plasminogen activator. During its interaction with plasminogen, staphylokinase is converted into a low molecular weight form by loss of ten amino-terminal residues. This low molecular weight form of recombinant staphylokinase has been crystallized using the hanging-drop vapor-diffusion technique with polyethylene glycol 4000 as precipitant. Crystals belong to the orthorhombic space group C2221 with unit-cell dimensions a = 43.78, b = 59.86 and c = 103.25 Å and one molecule in the asymmetric unit. These crystals diffract to about 2.4 Å resolution.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S090744499700084X