ISSN:
1600-5724
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
A procedure is presented for the stereochemically restrained least-squares refinement of macromolecular structures with neutron and X-ray diffraction data from single crystals. This procedure has been tested by refining a model of ribonuclease A using neutron data to minimal spacings of 2.8 Å and X-ray data from within 2.0 Å spacings. Joint X-ray and neutron refinement is well conditioned and tends to avoid false minima that may occur when a medium-resolution structure is refined solely with the neutron structure factors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S0567739482000527