ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Polystyrene
;
Ethyl acetate
;
Dichloromethane
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The reversed phase behaviour of high molecular mass polystyrenes was investigated on C18 bonded phase columns with ethyl acetate-methanol and ethyl acetateacetonitrile mobile phases. The results are compared with the corresponding dichloromethane mobile phases. The ethyl acetate-methanol mobile phase showed anomalous elution behaviour, similar to other previously investigated solvent combinations with methanol. The ethyl acetate-acetonitrile mobile phase showed no anomalous behaviour, increased retention and, elution over a wider composition range compared with the dichloromethane-acetonitrile system. However, resolution between adjacent molecular masses was considerably worse.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02274580
