ISSN:
1434-4475
Keywords:
Di-trifluoracetyl-N-ylide
;
Benzyl-dimethylammonium- and phenyl-dimethylammonium-acetic acid betaine
;
1,3-Dimethylammonium-butyl acetic acid betaine
;
1,4-Dimethylpiperazinium acetic acid betaine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The influence of substituents at the ammonium nitrogen of acetic acid betaines on the reaction with trifluoracetic anhydride (TFA) has been investigated. Thus benzyl-dimethyl- and phenyl-dimethyl-betaines (1a, 1b) as well as the bifunctional betaines derived from 1,3-bis-(dimethylamino)-butane (5) or 1,4-dimethylpiperazine (7) may serve as examples. From these betaines, the symmetrical compound7 gives in 50% yield 1,4-dimethyl-piperazinium-ditrifluoracetyl-dimethylide (8), while the tendency of formation of the di-acyl-N-ylides2a, 2b, and6 is rather low.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00809158
