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  • 1
    Electronic Resource
    Electronic Resource
    A two-backbone polymer model for interphase chromosome geometry (1997)
    Springer
    Bulletin of mathematical biology 59 (1997), S. 325-337 
    Details
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A polymer model for the overall geometric structure of a human chromosome during the G0/G1 portion of cell-cycle interphase is constructed, based on fluorescencein situ hybridization data on distances between defined genomic sequences. The model consists of flexible giant loops, averaging about 6 million base pairs, with two random-walk backbones; it involves essentially three parameters. Numerical results based on properly selected values of parameters fit the data well.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02462006
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