ISSN:
1435-604X
Keywords:
Laser hyperthermia
;
Mathematical model
;
Tumours
;
Optical coefficients
;
Optical fibres
;
Thermal diffusion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Physics
,
Technology
Notes:
Abstract A time dependent mathematical model of optical energy transfer and heat conduction in tissue with strong anisotropic scattering is used to analyse the results of experiments (1) in which the livers of rats were treated by local laser hyperthermia. Good qualitative agreement to the temperature distribution is possible, but satisfactory quantitative agreement is only possible if allowance is made for temperature dependence of the optical and thermal parameters. Analysis of the volume of tissue killed by the treatment shows a marked departure from the rule used in conventional hyperthermia to determine the region treated; the reason for this is not clear, but a number of possibilities are suggested.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02032509