Electronic Resource
Springer
Development genes and evolution
190 (1981), S. 365-369
ISSN:
1432-041X
Keywords:
Selector genes
;
Determination
;
Homoeotic mutations
;
Drosophila melanogaster
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary New alleles of thetrithorax locus have been isolated and analysed. The phenotypes of different allelic combinations confirm that a decrease or loss of function of the locus is responsible for homoeotic transformations of the adult thoracic and abdominal segments. Since neither these homoeotic transformations nor larval lethality are complemented by the previously described mutationRg-bx, it is concluded that the latter is an allele oftrithorax. The effect of near loss of function of thetrithorax locus after the completion of embryogenesis has been investigated by clonal analysis. This has produced two unexpected results: 1) there is a requirement for the activity of the locus after embryogenesis is completed; 2) the locus is required for the normal development of at least some mesothoracic structures. These results are discussed with respect to the selector gene hypothesis and other putative activator gene mutations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00863275
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