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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 3 (1966), S. 140-147 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Description / Table of Contents: Summary AfterX-irradiation two different types of yeast cells can be observed. The so-calledn-cells, which cannot grow to macrocolonies, are produced by a typical “yes-no”-reaction. Their further fate (giant cells) is independent of the applied absorbed dose. The other kind of cells, the so-calledm-cells, can grow to macrocolonies. They show afterX-irradiation an induced lagtime t lag 0 . The curvature of the proliferation curve during the lagtime t lag 1 is a measure for the spread of the population of m-cells. The normal spread of yeast cells is present also afterX-irradiation, indicating that all m-cells of the population got a radiation damage of the same magnitude. This radiation effect is not a “yes-no”-reaction since the length of the induced lagtime t lag 0 is dose dependent. Diploide and haploide yeast cells show the same general behaviour. Nevertheless the sensitivity for the induced lagtime t lag 0 is within a factor of about two higher in haploide cells. This indicates differences between those strains due to reactions, which can be regulated by the cell after irradiation.
    Notes: Zusammenfassung Nach Röntgenbestrahlung vonSaccharomyces Zellen entstehen im wesentlichen zwei Zelltypen (m- undn-Zellen), deren Schicksale direkt nach Bestrahlungsende quantitativ verfolgt werden.n-Zellen werden durch eine Reaktion vomjanein-Typ erzeugt, ihr weiteres Schicksal (Aufwachsen zu Riesenzellen) ist praktisch dosisunabhängig. Diem-Zellen zeigen nach Bestrahlung eine Lagzeit, deren Länge dosisabhängig ist. Haploide Zellen verhalten sich ebenso wie diploide Zellen; für die Induktion der Lagzeit beim-Zellen sind haploide Zellen um einen Faktor zwei strahlenempfindlicher. Ein kybernetisches Modell zur Beschreibung dieser Ergebnisse wird in einer folgenden Arbeit gegeben.
    Type of Medium: Electronic Resource
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