ISSN:
1432-0614
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Summary Paracoccus denitrificans was found to produce anaerobically a considerable amount of ubiquinone-10. A search for biosynthetic intermediates of ubiquinone-10 in the anaerobic culture disclosed a slight accumulation of 2-decaprenylphenol in the cells. The cellular content of ubiquinone-10 in continuous anaerobic culture decreased contrary to the increase of dilution rate. 2-decaprenylphenol was detected slightly in the cells throughout a whole range of dilution rates studied. It was inferred that the amount of precursors to 2-decaprenylphenol might have limited the biosynthesis of ubiquinone-10 at the higher dilution rates. As expected, an addition of precursors, p-hydroxybenzoate and mevalonate into the culture medium was successful for keeping the cellular content of ubiquinone-10 unchanged throughout the dilution rates examined, hence enhancing the productivity of ubiquinone-10.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00499856
