ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

Hits per page

hit 1 - 1 | 1 hit

Select All Export

Electronic Resource

Pharmacokinetics of oral and rectal flurbiprofen in children (1984)

Scaroni, C. ; Mazzoni, P. L. ; D'Amico, E. ; [et al.]

Springer

European journal of clinical pharmacology 27 (1984), S. 367-369

add to mindlist on the mindlist

Details

ISSN: 1432-1041

Keywords: flurbiprofen ; syrup ; suppository ; kinetics ; children ; bioavailability

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Eight subjects, aged 6–12 years and weighing 18.8–36.7 kg, received single doses of flurbiprofen 50 or 75 mg (corresponding to 1.4–2.7 mg/kg) as syrup and suppository in a Latin square design. Half-life (2.7–3.2 h), elimination constant (0.22–0.26 h−1), area under the plasma level curve (72.4–77.3 µg·h·ml−1) and time to reach the concentration peak (1–0.75 h) were similar after the syrup and suppository. Flurbiprofen showed equivalent bioavailability after oral and rectal administration and the same pharmacokinetic profile was confirmed in children as observed in adults.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00542178

	Location	Call Number	Expected	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit