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Altered chromatin structure associated with a partial trisomy of chromosome 7 in the mouse (1987)

Rake, A. V. ; Edwards, R. H.

Springer

Biochemical genetics 25 (1987), S. 671-686

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ISSN: 1573-4927

Keywords: Trisomy ; chromatin ; average nucleosome size ; mouse

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract The chromatin of a mouse that is trisomic for part of chromosome 7 was investigated. Chromatin from trisomic tissue has a smaller average nucleosome DNA repeat length than chromatin from tissue taken from normal diploid littermates. DNA of the nucleosome cores is the same size in both normal and trisomic tissues. Not all of the nucleosome monomers have different repeat lengths. Normal and trisomic mouse kidney cells in tissue culture maintained their nucleosome repeat-length differences.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00556211

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