ISSN:
1573-8221
Keywords:
visual deprivation
;
central visual system
;
structural proteins
;
disk electrophoresis in polyacrylamide gel
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The composition of membrane proteins of the visual cortex and superior colliculus of normal and visually deprived (for 2.5 months after birth) rabbits was studied by disk electrophoresis in polyacrylamide gel. Membrane proteins were extracted consecutively with 1% solution of Triton X-100 and 0.1% solution of sodium dodecylsulfate. One fraction, consisting of high-molecular-weight proteins, was not found in the membrane proteins of the central visual system of the light-deprived rabbits, and the relative percentage of proteins in the various fractions also differed from normal. It can be concluded from these results that visual deprivation gives rise to considerable quantitative and qualitative changes in the composition of the brain membrane proteins, with some specificity toward the central visual structures.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00799793
