ISSN:
1573-8221
Keywords:
heart
;
liver
;
Na,K-ATPase
;
lipid peroxidation
;
stress
;
adaptation to stress
;
adaptation to hypoxia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Na,K-ATPase activity is shown to be lowered more than twice 2 hours after emotional pain stress in comparison with the initial level, remaining practically unchanged during the subsequent 24 hours. Adaptation to repeated stress results in a 50% activation of Na,K-ATPase. A protective effect is demonstrated in long-term stress against the background of preadaptation. Adaptation to periodic hypoxia inhibits liver Na,K-ATPase to the same extent as does acute stress. Against the background of preadaptation to periodic hypoxia, stress does not aggravate the drop of Na,K-ATPase activity. Adaptation to stress inhibits accumulation of products ofin vitro-induced lipid peroxidation in the heart 1.4-fold and does not affect it in the liver, whereas adaptation to hypoxia sharply accelerates the accumulation of oxidized products in both organs, which probably explains the activation of liver Na,K-ATPase in adaptation to stress and its inhibition in adaptation to hypoxia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02446724
