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Thermal analysis of amorphous phase in a pharmaceutical drug (1997)

Fagegaltier, N. ; Lamure, A. ; Lacabanne, C. ; [et al.]

Springer

Journal of thermal analysis and calorimetry 48 (1997), S. 459-464

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ISSN: 1572-8943

Keywords: amorphous phase ; pharmaceutical drug ; relaxations and transitions ; Thermally Stimulated Current

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology

Notes: Abstract Thermally Stimulated Current (TSC) spectroscopy and Differential Scanning Calorimetry (DSC) have been applied to the characterization of the microstructure of a pharmaceutical drug. The dielectric relaxation spectrum shows two modes located in the temperature range of the glass transition. They have been attributed to the molecular mobility in the “true amorphous phase” and in the ≪rigid amorphous region≫.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01979492

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