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Protein phosphorylation and the role of Ca2+ in planarian turbellarian regeneration (1986)

Moraczewski, J. ; Martelly, I. ; Franquinet, R.

Springer

Hydrobiologia 132 (1986), S. 223-227

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ISSN: 1573-5117

Keywords: DNA synthesis ; protein kinases ; phosphorylation ; regeneration ; calcium ; calmodulin

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Abstract During planarian regeneration, relationships in timing were established between variations of calcium and calmodulin contents on one hand, and protein phosphorylation and stimulation of DNA and RNA synthesis on the other. Special attention was paid to changes in histone phosphorylation in regenerating fragments. Using in vitro experiments on dissociated planarian cells, we demonstrated causal relationships between these events. In particular, the key role of Ca2+ in the activation of protein kinases and in the initiation of DNA synthesis was emphasized.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00046252

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