ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Conclusions 1. 2-Acylthiopyrimidines and 1-acyl-4,6-diamino-1,2-dihydro-2-pyrimidinethiones react with nucleophilic reagents to give 2-mercaptopyrimidines and the corresponding carboxylic acid derivatives. 2. The 6-amino-4-acylamido-1H(3H)-dihydro-2-pyrimidinethiones are acylated by acyl halides either at the S atom or at the NH2 group, while their salts are alkylated by alkyl halides at the S atom. 3. 2-Acylthio-4,6-diaminopyrimidines and 1-acyl-4,6-diamino-1,2-dihydro-2-pyrimidinethiones are capable of rearranging to the isomeric acyl derivatives.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00949231