ISSN:
1573-4986
Keywords:
1H-NMR spectroscopy
;
13C-NMR spectroscopy
;
FAB-MS
;
milk oligosaccharides
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The structure of a nonasaccharide and of two decasaccharides isolated from human milk has been investigated by using methylation, fast atom bombardment mass spectrometry and1H-/13C-nuclear magnetic resonance spectroscopy. The structures of these oligosaccharides were: $$\begin{gathered} trifucosyllacto - N - hexaose; \hfill \\ Fuc\alpha 1 - 2Gal\beta 1 - 3(Fuc\alpha 1 - 4)GlcNAc\beta 1 - 3[Gal\beta 1 - 4(Fuc\alpha 1 - 3)GlcNAc\beta 1 - 6]\beta 1 - 4Glc, \hfill \\ difucosyllacto - N - octaoses; \hfill \\ Gal\beta 1 - 3(Fuc\alpha 1 - 4)GlcNAc\beta 1 - 3Gal\beta 1 - 4(Fuc\alpha 1 - 3)GlcNAc\beta 1 - 6)[Gal\beta 1 - 3GlcNAc\beta 1 - \hfill \\ 3]Gal\beta 1 - 4Glc \hfill \\ \end{gathered} $$ and $$\begin{gathered} Gal\beta 1 - 3GlcNAc\beta 1 - 3Gal\beta 1 - 4(Fuc\alpha 1 - 3)GlcNAc\beta 1 - 6)[Fuc\alpha 1 - 2Gal\beta 1 - 3GlcNAc\beta 1 - 3]Gal\beta 1 - \hfill \\ 4Glc. \hfill \\ \end{gathered} $$ The two decasaccharides possess a new type of core structure proposed to be namediso-lacto-N-octaose.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01050646