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Inhibition ofSaccharomyces cerevisiae division by 5-trifluoro-methyl-6-azauracil (1984)

Jirků, V. ; Petřiková, D. ; Škoda, J.

Springer

Cellular and molecular life sciences 40 (1984), S. 1159-1161

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ISSN: 1420-9071

Keywords: Saccharomyces cerevisiae ; 5-trifluoromethyl-6-àzauracil ; yeast cell cultures ; cell division ; inhibition of

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Cell division, as studied in asynchronous cultures of yeast cells, is sensitive to 5-trifluoromethyl-6-azauracil (F3CAzU). Under defined conditions (10 mmoles l−1 F3CAzU) this compound blocks immediately and completely the process of cell division. Using synchronized cells, the time-point at which division process of yeast cell can be inhibited by F3CAzU has been determined. The inhibitor effect of this compound is completely reversed by thymine, thymidine and uracil.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01971472

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