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Modification by calcium dobesilate of histamine effects on capillary ultrastructure (1975)

Mestres, P. ; Rodriguez, L. ; Erill, S. ; [et al.]

Springer

Cellular and molecular life sciences 31 (1975), S. 826-829

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ISSN: 1420-9071

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary The ultrastructure of blood capillaries and venules are studied in rat skin. After i.v. injection of histamine the luminal surface of the endothelial cells show protrusions of variable size. Numerous gaps have be found in the capillary wall, specially in the venules. These alterations are not observed in the animals that were treated with calcium dobesilate before the administration of histamine. In these cases the capillary structure are indistinguishable of the controls. The possible effects of the histamine and calcium dobesilate on the cell coat and cell junctions of the endothelial capillary cells are discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01938489

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