ISSN:
1523-9829
Source:
Annual Reviews Electronic Back Volume Collection 1932-2001ff
Topics:
Technology
,
Medicine
Notes:
Abstract Driven by advances in the acquisition of genetic sequence information and the ability to manipulate small quantities of nucleic acid, a number of technologies are emerging that exploit nucleic acids for research, diagnostic, and therapeutic utility. In this review, we cover three technologies based on nucleic acids-DNA microarrays, antisense technology, and gene therapy-that are especially promising and may make a substantial impact in the laboratory and in the clinic during the coming years. For each of these areas, an overview of the current status and applications is provided, followed by a discussion of critical issues and challenges to be faced for further advancement of the technology; an emphasis is placed on quantitative and engineering aspects.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1146/annurev.bioeng.1.1.265
