ISSN:
0887-624X
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A new route to polyamides containing optically active thymine groups as pendants has been established. The method is based on the grafting of (-) and (±)-2-(thymin-1-yl)propionic acid [(-) and (±) TPA] onto a polyamide containing hydroxyl groups. The hydroxy polyamide was prepared by selective N-acylation of an active diester of N-hydroxy-5-norborene-2,3-dicarboxamide (HONB), N,N'-(isophthaloyl-dioxy)-bis(5-norbornene-2,3-dicarboximide) (IPBONB), with 1,3-diamino-2-hydroxypropane (AHP). Model compounds (-) and (±)-(1,3-dibenzoylamino-2-propyl)2-(thymin-1-yl)propionate[(-) and (±) (BAPTP)] were prepared by direct, low-temperature esterification before synthesizing the polymer.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/pola.1986.080240206
