ISSN:
0021-8995
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
,
Physics
Notes:
Chloromethylstyrene 1 (mixture meta and para; 60/40) can be oxydized in corresponding aldehyde 2. Vinylbenzaldehyde 2 reacts with primary amines such as aniline, benzylamine, 2-phenylethylamine, 3-phenylpropylamine, and 2-aminopyridin to give Schiff bases that are polymerized in bulk with a radical initiator. Poly(vinyl benzaldehyde) 6 prepared from corresponding monomer 2 also reacts with primary amines to give polymeric Schiff bases. Hydrolyses of these polymeric imines have been carried out either in heterogeneous acidic medium or basic heterogeneous medium; a suitable percentage of amines has been released after some hours. Finally, a study of hydrolysis and of diffusion of released amines in a dosage form (Eudragit RL) has been also carried out with some polymeric Schiff bases.
Additional Material:
10 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/app.1991.070431007
