ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Thermitase - A Thermostable Serine Protease. I. Synthesis of Alanine Peptide Esters as Substrates of the EnzymeThe synthesis of N-acetylated and N-succinylated peptide esters of alanine is described. The peptides are built up from the Z-Abkürzung: Z = Benzyloxycarbonyl, Ac = Acetyl, Suc = Succinyl, OMe = Methylester, MA = Mischanhydridmethode, E = Ether, PE = Petrolether, Etac = Ethylacetat, AcOH = Essigsäure, Dibu = n-Dibutylether, DMSO = Dimethylsulfoxid, DMF = Dimethylformamid, TEA = Triethylamin, Ac2O = Essigsäureanhydrid protected peptides by liquid phase fragment condensation and by acylation of the deprotected peptide esters. The kinetic parameters K m and K cat of some compounds are presented.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19843260106
