ISSN:
1434-193X
Keywords:
Ancistrotermescavithorax
;
Configuration determination
;
Premnaoligotricha
;
Terpenoids
;
Total synthesis
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The absolute configuration of the antibacterial sesquiterpene, 7-hydroxy-6,11-cyclofarnes-3(15)-en-2-one (2), was determined as (6R,7R) by the synthesis of its opposite enantiomer (6S,7S)-2 from (S)-2-(2,2-dimethyl-6-methylenecyclohexyl)ethanol (1). This versatile building block (S)-1 was also converted to (R)-ancistrodial (3).
Type of Medium:
Electronic Resource