ISSN:
0009-2940
Keywords:
Zinc complexes
;
Cysteine ligands
;
Histidine ligands
;
Imidazole ligands
;
Pyrazolylborate ligands
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Highly substituted pyrazolylborate ligands TpR,Me were used to limit the coordination number of zinc towards cysteine- and histidine-derived coligands. Monodentate thiolate attachment (→ 1a-f) was achieved with N- and C-protected cysteine, monodentate carboxylate attachment (→ 3) with N-protected histidine. C-protected cysteine was found to form a five-membered N,S-chelate ring (2). While imidazole coordination with N- and C-protected histidine could not be achieved, cationic pyrazolylborate-zinc-coligand complexes [TpZn-L]+ (4a, b) were obtained for L = 2-methylimidazole. The new complexes were characterized by their spectra and three structure determinations.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19961291017
