ISSN:
0009-2940
Keywords:
Erythronolide A
;
Allylboration, stereoselective
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Starting from building block 3 comprising the C-7 to C-15 segment of erythronolide A, a linear synthesis of erythronolide A has been achieved. Key steps were a Sharpless-epoxidation to set up the sterocenter at C-6, and two stereoselective allylboration reactions to generate the stereocenters at C-2, C-3, C-4, and C-5.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19941271225