ISSN:
0009-2940
Keywords:
Quinolin-2(1H)-ones
;
4-amino-3-pyridinio-
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
4-Amino-3-pyridinioquinolin-2(1H)-one Chlorides and 3,4-Diaminoquinolin-2(1H)-onesN;-(Chloroacetyl)anthranilonitriles 1 react with the pyridines 2 to form the 4-amino-3-pyridinioquinolin-2(1H)-one chlorides 4, which are converted into the pyrido[1',2′ : 1,2]imidazo[5,4-c]- quinolin-6(5H)-ones 6 in the presence of sodium hydroxide or by cyclooxidation with bromine. Treatment of 4 with hydrazine hydrate yields the 3,4-diaminoquinolin-2(1H)-ones 9. Analogously to other o-diamines the substituted imidazo [4,5-c]- quinolinones 12, the pyrazino[2,3-c]quinolinones 13, 14, the 1,2,5-thiadiazolo[3,4-c]quinolin-4-one 15a and the 1,2,5-selena-diazolo[3,4-c]quinolin-4-one 15b are obtainable from 9a. With chloroacetyl chloride 9a provides the oxazino[2,3-b]quinolin-2-one 11.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19911240542
