ISSN:
0021-9541
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
An attempt has been made to locate RNA as a structural component of the peripheries of cultured cells derived from a human osteogenic sarcoma, and L1210 mouse leukaemia cells. In the case of cells derived from the osteogenic sarcoma, their detachment from glass was facilitated by incubation with ribonuclease; on removal from glass, they left cellular “footprints” behind, which were visulized in radioautographs of cells previously labeled with tritiated uridine, and removable with ribonuclease. The electrophoretic data show loss of charge by both types of cell following incubation with ribonuclease.These results are interpreted to indicate that RNA is a structural component of the peripheries of these cells. No attempt is made to speculate on the obvious biological improtance of these observations if they are applicable to cells in general.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jcp.1040680314
