ISSN:
0362-2525
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
The administration of insulin to Triturus cristatus confirms its action in depletion of the adrenalin (A) granules of the adrenal chromaffin cells and the subsequent activation of phenylethanolamine-N-methyltransferase (PNMT). Treatment was carried out in March, when noradrenalin (NA) and A granules are present in almost equal quantities in the chromaffin cells, and in June, when NA granules largely prevail. After insulin administration, adrenalin content of the specimens treated in March decreases from 2.44 granules/μm2 to 0.28 granules/μm2; on the other hand, adrenalin content of the specimens treated in June increases from 0.19 granules/μm2 to 0.31 granules/μm2. These results suggest that in T. cristatus insulin acts both as an adrenalin-releasing agent and as a stimulator of PNMT activity.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jmor.1052110110
