ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
In vivo and in vitro experiments described herein have demonstrated that the GBH coating is antithrombogenic when placed on PVC, as tested in the blood system of rabbits for periods up to 2 weeks. In vitro clotting times cannot be correlated with the in vivo thrombogenicity of the same implants. For example, dog and man have very similar in vitro clotting times, but very dissimilar in vivo prosthetic thrombosis problems. In vivo and in vitro tests are for the most part not comparable in that they do not measure the same things. However, both in vivo and in vitro tests proved the GBH-treated vinyl to be antithrombogenic. It may be concluded from the available data that a flexible plastic can be treated with GBH and become antithrombogenic for a practicable period of time.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jbm.820010407
