ISSN:
0006-3592
Keywords:
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
In order to develop a more economical separation method and to determine the feasibility of such a method for the recovery of gentamicin from fermentation broth, a foam separation process was evaluated using a batch system. The effects of such process variable as surface-active agent, pH, collector-colligent ratio, and the gas flow rate on the separation efficiency of gentamicin were studied. Form the experimental results, the optimal operating conditions selected were: pH below 9.0, collector-to-colligent ratio of 3, and airflow rate at 0.5 vol air/vol liquid/min. Under these operation conditions, the average recovery efficiency of gentamicin was 73% when sodium dodecyl sylfate was used as a collector. A mathematical expression for the foam separation rate was derived. The theoretically predicted values of separation efficiencies agreed reasonably well with the experimental results.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bit.260211111
