ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Empirical force-field calculations and ir and 1H-nmr spectra indicate that five-membered (C5) and seven-membered (C7eq) hydrogen-bonded rings are the preferred conformations of acetyl-L-Phe p-acetyl and p-valeryl anilides in nonpolar media. The C5/C7eq ratio was found to be dependent on the dryness of the solute and the solvent. This fact and the results from conformational-energy calculations suggest that a molecule of water participates in the stabilization of the C7eq conformation.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.360220605