ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The effects of deuteration and of changes in solvent composition on the thermo dynamics of the helix-coil transition have been studied by calorimetric and optical measurements in the poly-γ-benzyl-L-glutamate-dichloroacetic acid-1,2-dichloro-ethanc system. For a given solvent composition, deuteration of the polypeptide and of the acid lowers the transition temperature Tc, while an increase in the volume fraction of acid in the solvent raises Tc. A rise in Tc is accompanied by a decrease in both the van't Hoff and the calorimetric heats of transition, but at different rates. The result is a temperature dependency in the Zimm-Bragg cooperation parameter σ. Possible causes of this result and its implications are discussed.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.1966.360040906
