ISSN:
0263-6484
Keywords:
Chromatin
;
phospholipids
;
hepatocytes
;
development
;
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
The chromatin extracted from rat hepatocytes of different ages has been shown to contain a phospholipid fraction representing 0·47-0·59 per cent of total chromatin in newborn animals and 0·22 per cent in 45-day-old animals. No such age-related differences are observed in the nuclei.The phospholipid composition of the nuclei at different ages shows a higher level of sphingomyelin and a lower level of phosphatidylserine in newborn than in adult animals. Chromatin phospholipids have a completely different composition from that of nuclei with respect to age, particularly in newborn rats, where there is a decrease in phosphatidylcholine and an increase in phosphatidylserine.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cbf.290090209
