Publication Date:
2023-12-21
Description:
Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
Keywords:
R5-920
;
RC581-607
;
ILCs
;
inflammation
;
NK cell subsets
;
immunotherapy
;
anti-viral responses
;
anti-tumor responses
;
immune checkpoints
;
bic Book Industry Communication::M Medicine
Language:
English
Format:
image/jpeg
