Publication Date:
2015-04-26
Description:
Article REGγ, a proteasome activator, is associated with multiple oncogenic pathways in human cancers and can promote the degradation of multiple proteins including p53. Here the authors highlight a potential role for REGγ in skin cancer and propose a molecular mechanism linking p38 MAPK and Wnt signalling. Nature Communications doi: 10.1038/ncomms7875 Authors: Lei Li, Yongyan Dang, Jishen Zhang, Wangjun Yan, Wanli Zhai, Hui Chen, Ke Li, Lu Tong, Xiao Gao, Ali Amjad, Lei Ji, Tiantian Jing, Ziwei Jiang, Kaixuan Shi, Liangfang Yao, Dianwen Song, Tielong Liu, Xinghai Yang, Cheng Yang, Xiaopan Cai, Wei Xu, Quan Huang, Jin He, Jian Liu, Tenghui Chen, Robb E. Moses, Junjiang Fu, Jianru Xiao, Xiaotao Li
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics