ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The aim of this study is to fabricate an implant framework for tissue engineering bysintering titanium beads and coating with hydroxyapatite and test its biocompatibility andbioactivity in vitro. The porous titanium with and without hydroxyapatite coating were involved instudy groups. Osteoblastic proliferation, activity of alkaline phosphatase, mRNA of osteocalcin andbone sialoprotein were detected by MTT-assay, ALP test and real-time polymerase chain reactionrespectively. The results indicated that the porous titanium material with/without HA coating couldpromote osteoblastic proliferation significantly contrast to the control group. However, only poroustitanium with HA coating increased alkaline phosphatase, osteocalcin and bone sialoprotein geneexpression apparently and had statistically differences with the other two groups.Abstract no. is TE-Po-044
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.613.pdf
