Electronic Resource
Springer
Journal of comparative physiology
139 (1980), S. 109-115
ISSN:
1432-136X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The atrial adrenoceptors of the rainbow trout heart (Salmo gairdneri) were characterized in spontaneously beating preparations at 8 °C. The order of affinity for the inotropic and chronotropic responses was: Isoprenaline 〉 adrenaline ∼ salbutamol 〉 phenylephrine ∼ noradrenaline. Selective agonists and antagonists for mammalian α- and β1-adrenoceptors were without effect on the trout preparations. A potent neuronal uptake for adrenaline and noradrenaline could be demonstrated by means of cocaine blockade, consistent with considerable sympathetic innervation of the trout atrium. The results show that catecholamines increase the force and frequency of the atrium via a single, β2-type of adrenoceptor. It is suggested that there is no distinction between the “innervated” and the “humoral” β-adrenoceptors in the myocardium of this species.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00691024
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