ISSN:
0021-9304
Schlagwort(e):
Chemistry
;
Polymer and Materials Science
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Medizin
,
Technik allgemein
Notizen:
Bioelectric charge transfer between blood and the vascular wall appears to play a significant role in maintaining vascular homeostasis. Since the surface charge characteristics of the vessel wall are a function of the dielectric properties of the material, a study was made of the dielectric characteristics of various ion permeable materials and their relationship to electrokinetic phenomena and thrombogenicity. The dielectric properties of the ion permeable materials and of animal tissue were determined and found to be strikingly similar. Several models of electrodiffusion phenomena are reviewed with respect to dielectric properties. The electro-osmotic characteristics of animal tissue and ion permeable materials were investigated, and it was found that animal tissue exhibited electro-osmotic characteristics to a greater degree than did any other man-made materials. The propensity of a material to electro-osmose could not be predicted from the dielectric properties. In addition, no correlation could be found between thrombogenicity and dielectric properties. Dielectric relaxation phenomena is reviewed, and its possible contribution to nonthrombogenicity through the generation of a uniform, constant wall surface charge is presented. It is concluded that to mimic the ion content and mobility characteristics of animal tissue, as determined by dielectric properties, is insufficient to preclude thrombus formation.
Zusätzliches Material:
5 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jbm.820070507
