Publication Date:
2018-05-24
Description:
Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes Protein polarization driven by nucleoid exclusion of DnaK(HSP70)–substrate complexes, Published online: 23 May 2018; doi:10.1038/s41467-018-04414-2 Many bacterial proteins exhibit spatially defined localization important for function. Here the authors show that the polar localization of Shigella IpaC type III secretion substrate is mediated by its interaction with the DnaK chaperone and occlusion by the bacterial nucleoid.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics