Publikationsdatum:
2015-04-25
Beschreibung:
Article Guidepost cells provide guidance cues that orient growing axons in the brain but little is known about the midline guidepost cells that populate the mouse anterior commissure (AC). Here, the authors show that the transcription factor Nkx2.1 regulates the differentiation of astroglia and neurons that cooperate to guide AC axons through the expression of Slit2. Nature Communications doi: 10.1038/ncomms7887 Authors: Shilpi Minocha, Delphine Valloton, Athena R. Ypsilanti, Hubert Fiumelli, Elizabeth A. Allen, Yuchio Yanagawa, Oscar Marin, Alain Chédotal, Jean-Pierre Hornung, Cécile Lebrand
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik