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  • Books  (61)
  • Medicine  (61)
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  • 1
    Unknown
    Cham : Springer
    Keywords: Medicine ; Molecular biology ; Health promotion ; Cardiology ; Diabetes ; Endocrinology ; Metabolic diseases ; Biomedicine ; Molecular Medicine ; Health Promotion and Disease Prevention ; Endocrinology ; Cardiology ; Diabetes ; Metabolic Diseases
    Description / Table of Contents: Introduction --- Human brown adipose tissue plasticity: hormonal and environmental manipulation --- The energy sensor AMPK: Adaptations to exercise, nutritional and hormonal signals --- Plasma steroids and cardiorespiratory fitness response to regular exercise --- Sending the signal: Muscle glycogen availability as a regulator of training adaptation --- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle --- Skeletal muscle microRNAs: Roles in differentiation, disease and exercise --- Tryptophan-kynurenine metabolites in exercise and mental health --- FNDC5/irisin - their role in the nervous system and as a mediator for beneficial effects of exercise on the brain
    Pages: Online-Ressource (X, 102 pages)
    ISBN: 9783319727905
    Language: English
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  • 2
    Keywords: Life sciences ; Hydrology ; Environmental sciences ; Agriculture ; Life Sciences ; Agriculture ; Hydrology/Water Resources ; Environmental Science and Engineering
    Description / Table of Contents: Foreword --- Summary --- 2. In-Situ Destructive Sampling --- 2.1 The Concept of Representivity --- 2.2 Plant Sampling Pattern and Design --- 2.3 Biomass Water Equivalent --- 2.4 Conclusions --- 3. Remote Sensing via Satellite Imagery Analysis --- 3.1 Photo-Reflective Properties of Plants --- 3.2 Satellite Image Analysis --- 3.3 Conclusions --- 4. Estimate of Biomass Water Equivalent via the Cosmic Ray Neutron Sensor --- 4.1 The role of Biomass in the CRNS Calibration --- 4.2 Relationship between Neutrons and Crop Biomass --- 4.3 Dire4ct Relationship between Neutrons and Biomass --- 4.4 Conclusions
    Pages: Online-Ressource (X, 33 pages) , 18 illustrations, 14 illustrations in color
    ISBN: 9783319695396
    Language: English
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  • 3
    Keywords: Medicine ; Neurosciences ; Pharmacology ; Neurology ; Biomedicine ; Neurosciences ; Neurology ; Pharmacology/Toxicology
    Description / Table of Contents: 1.Overview --- 2.In vivo imaging of nicotinic acetylcholine receptors in the central nervous system --- 3.A new aspect of cholinergic transmission in the central nervous system --- 4.Nicotinic acetylcholine receptor signaling: roles in neuroprotection --- 5.Regulation by nicotinic acetylcholine receptors of microglial glutamate transporters: role of microglia in neuroprotection --- 6.Shati/Nat8l and N-acetylaspartate (NAA) have important roles in regulating nicotinic acetylcholine receptors in neuronal and psychiatric diseases in animal models and humans --- 7.Nicotinic acetylcholine receptors in regulation of pathology of cerebrovascular disorders --- 8.Roles of nicotinic acetylcholine receptors in the pathology and treatment of Alzheimer’s and Parkinson’s diseases --- 9.SAK3-induced neuroprotection is mediated by nicotinic acetylcholine receptors --- 10.Removal of blood amyloid as a therapeutic strategy for Alzheimer’s disease: the influence of smoking and nicotine
    Pages: Online-Ressource (X, 191 pages) , 62 illustrations, 20 illustrations in color
    ISBN: 9789811084881
    Language: English
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  • 4
    Unknown
    Cham : Springer
    Keywords: Life sciences ; Forest products ; Plant anatomy ; Plant development ; Plant physiology ; Life Sciences ; Plant Anatomy/Development ; Plant Physiology ; Plant Systematics/Taxonomy/Biogeography ; Wood Science & Technology
    Description / Table of Contents: Introduction --- Preparation techniques - Making anatomical structures visible --- Morphology of the plant body --- Cellular composition of the plant bodies --- Structure of cell walls and cell contents --- Primary, secondary and tertiary meristem --- Stem anatomical structures of major taxonomic units --- Evolution of stems --- Anatomical adaptions to permanent changed environmental conditions --- Anatomical adaptions to temporarily changed environmental conditions --- Coexistence of algae, fungi and vascular plants --- Wood decay --- Fossilization, permineralization, coalification, carbonization and wetwood conservation --- Technically altered wood products
    Pages: Online-Ressource (VII, 207 pages)
    ISBN: 9783319735245
    Language: English
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  • 5
    Keywords: Life sciences ; Agriculture ; Plant breeding ; Life Sciences ; Plant Breeding/Biotechnology ; Agriculture
    Description / Table of Contents: General Introduction --- Screening Protocols for Heat Tolerance in Rice at the Seedling and Reproductive Stages --- Validation of Screening Protocols for Heat Tolerance in Rice --- Conclusion --- References
    Pages: Online-Ressource (XII, 39 pages) , 16 illustrations, 10 illustrations in color
    ISBN: 9783319773384
    Language: English
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  • 6
    Keywords: Life sciences ; Ecosystems ; Aquatic ecology ; Conservation biology ; Ecology ; Nature conservation ; Marine sciences ; Freshwater ; Life Sciences ; Freshwater & Marine Ecology ; Ecosystems ; Conservation Biology/Ecology ; Nature Conservation ; Marine & Freshwater Sciences
    Description / Table of Contents: Chapter 1. Challenges in Riverine Ecosystem Management --- Part I Human Impacts, Mitigation and Restoration --- Chapter 2. Historic Milestones of Human River Uses and Ecological Impacts --- Chapter 3. River Morphology, Channelization, and Habitat Restoration --- Chapter 4. River Hydrology, Flow Alteration, and Environmental Flow --- Chapter 5. Hydropeaking Impacts and Mitigation --- Chapter 6. Dams: Ecological Impacts and Management --- Chapter 7. Aquatic Habitat Modeling in Running Waters --- Chapter 8. The Role of Sediment and Sediment Dynamics in the Aquatic Environment --- Chapter 9. River Connectivity, Habitat Fragmentation and Related Restoration Meas --- Chapter 10. Phosphorus and Nitrogen Dynamics in Riverine Systems: Human Impacts and Management Options --- Chapter 11. Climate Change Impacts in Riverine Ecosystems --- Chapter 12. Ecotoxicology --- Chapter 13. Land Use --- Chapter 14. Recreational Fisheries – The Need for Sustainability in Fisheries Management of Alpine Rivers --- Part II Management, Methodologies, Governance --- Chapter 15. Restoration in Integrated River Basin Management --- Chapter 16.Adaptive Management of Riverine Socio-ecological Systems --- Chapter 17. Legislative Framework for River Ecosystem Management on International and European Level --- Chapter 18. Ensuring Long-Term Cooperation Over Transboundary Water Resources Through Joint River Basin Management --- Chapter 19. Biomonitoring and Bioassessment --- Chapter 20. Biodiversity and Freshwater Information Systems --- Chapter 21. Ecosystem Services in River Landscapes --- Chapter 22. Public Participation and Environmental Education --- Chapter 23. NGOs in Freshwater Resource Management --- Part III Case Studies --- Chapter 24. Danube Under Pressure: Hydropower Rules the Fish --- Chapter 25. Danube Floodplain Lobau --- Chapter 26. Danube Sturgeons: Past and Future --- Chapter 27. Healthy Fisheries Sustain Society and Ecology in Burkina Faso --- Chapter 28. The Tisza River: Managing a Lowland River in the Carpathian Basin --- Part IV Summary --- Chapter 29. Landmarks, Advances and Future Challenges in Riverine Ecosystem Management
    Pages: Online-Ressource (VII, 571 pages) , 123 illustrations, 82 illustrations in color
    ISBN: 9783319732503
    Language: English
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  • 7
    Unknown
    Berlin, Heidelberg : Springer
    Keywords: Biochemistry ; Chemistry, Organic ; Medicine ; Toxicology
    ISBN: 9783540742296
    Language: English
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  • 8
    Keywords: Life sciences ; Cell biology ; Developmental biology ; Plant science ; Botany ; Life Sciences ; Developmental Biology ; Plant Sciences ; Cell Biology
    Description / Table of Contents: Part 1 Sperm Attraction, Activation and Acrosome Reaction --- 1 Sperm Chemotaxis: The First Authentication Events Between Conspecific Gametes Prior to Fertilization (Manabu Yoshida) --- 2 Respiratory CO2 Mediates Sperm Chemotaxis in Squids (Noritaka Hirohashi) --- 3 Specific Mechanism of Sperm Storage in Avian Oviducts (Tomohiro Sasanami) --- 4 Allurin: Exploring the Activity of a Frog Sperm Chemoattractant in Mammals (Douglas E. Chandler) --- 5 Structure, Function and Phylogenetic Consideration of Calaxin (Kazuo Inaba) --- 6 Cl- Channels and Transporters in Sperm Physiology (Alberto Darszon) --- 7 Equatorin-related Subcellular and Molecular Events During Sperm Priming for Fertilization in Mice (Kiyotaka Toshimori) --- 8 Acrosome Reaction-mediated Motility Initiation that is Critical for the Internal Fertilization of Urodele Amphibians (Akihiko Watanabe) --- 9 Analysis of the Mechanism that Brings Protein Disulfide Isomerase-P5 to Inhibit Oxidative Refolding of Lysozyme (Miho Miyakawa) --- Part 2 Gametogenesis, Gamete Recognition, Activation, and Evolution --- 10 Effect of Relaxin-like Gonad-Stimulating Substance (GSS) on Gamete Shedding and 1-Methyladenine Production in Starfish Ovaries (Masatoshi Mita) --- 11 Incapacity of 1-Methyladenine Production to Relaxin-like Gonad-Stimulating Substance (GSS) in Ca2+-free Seawater-treated Starfish Ovarian Follicle Cells (Masatoshi Mita) --- 12 Novel Isoform of Vitellogenin Expressed in Eggs is a Binding Partner of the Sperm Proteases, HrProacrosin and HrSermosin, in the Ascidian Halocynthia roretzi (Hitoshi Sawada) --- 13 Actin Cytoskeleton and Fertilization in Starfish Eggs (Luigia Santella) --- 14 Focused Proteomics on Egg Membrane Microdomains to Elucidate the Cellular and Molecular Mechanisms of Fertilization in the African Clawed Frog Xenopus laevis (Ken-ichi Sato) --- 15 Egg Activation in Polyspermy: Its Molecular Mechanisms and Evolution in Vertebrates (Yasuhiro Iwao ) --- 16 ATP Imaging in Xenopus laevis Oocyte (Takashi Ijiri) --- 17 Mitochondrial Activation and Nitric Oxide (NO) Release at Fertilization in Echinoderm Eggs (Tatsuma Mohri) --- 18 Functional Roles of Spe Genes in the Male Germline During Reproduction of Caenorhabditis elegans (Hitoshi Nishimura) --- 19 Origin of Female/Male Gender as Deduced by the Mating Type Loci of the Colonial Volvocalean Greens (Hisayoshi Nozaki) --- Part 3 Allorecognition in Male–Female Interaction --- 20 Allorecognition and Lysin Systems During Ascidian Fertilization (Hitoshi Sawada) --- 21 Self-incompatibility in the Brassicaceae (Megumi Iwano) --- 22 Signalling Events in Pollen Acceptance or Rejection in the Arabidopsis Species (Daphne R. Goring) --- 23 Papaver rhoeas S-Determinants and the Signaling Networks they Trigger (Vernonica E. Franklin-Tong ) --- 24 S-RNase-based Self-incompatibility in Petunia: A Complex Non-self Recognition System Between Pollen and Pistil (Teh-hui Kao) --- 25 Self-incompatibility System of Ipomoea trifida, a Wild-type Sweet Potato (Tohru Tsuchiya) --- Part 4 Male–Female Interaction and Gamete Fusion --- 26 Profiling the GCS1-based Gamete Fusion Mechanism (Toshiyuki Mori) --- 27 Fertilization Mechanisms of the Rodent Malarial Parasite Plasmodium berghei (Makoto Hirai) --- 28 Sexual Reproduction of a Unicellular Charophycean Alga, Closterium peracerosum-strogosum-littorale Complex (Hiroyuki Sekimoto) --- 29 Fertilization of Brown Algae: Flagellar Function in Phototaxis and Chemotaxis (Taizo Motomura ) --- 30 Gene and Protein Expression Profiles in Rice Gametes and Zygotes: A Cue for Understanding the Mechanisms of Gametic and Early Zygotic Development in Angiosperms (Takashi Okamoto) --- 31 Role of CD9 in Sperm-Egg Fusion and Virus-induced Cell Fusion in Mammals (Kenji Miyado) --- 32 The Mechanism of Sperm-Egg Fusion in Mouse and the Involvement of IZUMO1 (Naokazu Inoue) --- 33 A ZP2 Cleavage Model of Gamete Recognition and the Post-fertilization Block to Polyspermy (Jurrien Dean) --- 34 Involvement of Carbohydrate Residues of the Zona Pellucida in In Vitro Sperm Recognition in Pigs and Cattle (Naoto Yonezawa) --- Part 5 Organella, Proteolysis, and New Techniques --- 35 The Role of Peroxisomes in Plant Reproductive Processes (Shoji Mano) --- 36 Regulation of Vacuole-mediated Programmed Cell Death During Innate Immunity and Reproductive Development in Plants (Tomoko Koyano) --- 37 Sperm Proteasomes as a Putative Egg Coat Lysin in Mammals (Peter Sutovsky) --- 38 Germline Transformation in the Ascidian Ciona intestinalis (Yasunori Sasakura) --- BM Index.  
    Pages: Online-Ressource (XII, 480 pages) , 127 illustrations, 102 illustrations in color
    ISBN: 9784431545897
    Language: English
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  • 9
    Unknown
    Cham : Springer
    Keywords: Life sciences ; Aquatic ecology ; Life Sciences ; Freshwater & Marine Ecology
    Description / Table of Contents: Foreword --- Preface --- Part 1 A brief history of marine litter research --- Part 2 Abiotic aspects of marine litter pollution --- Global distribution, composition and abundance of marine litter --- Persistence of plastic litter in the oceans --- Part 3 Biological implications of marine litter --- Deleterious effects of litter on marine life --- The complex mixture, fate and toxicity of chemicals associated with plastic debris in the marine environment --- Marine litter as habitat and dispersal vector --- Part 4 Micro plastics --- Micro plastics in the marine environment: sources, consequences and solutions --- Methodology used for the detection and identification of micro plastics – a critical appraisal --- Sources and pathways of micro plastics to habitats --- Micro plastics in the marine environment: distribution, interactions and effects --- Modeling the role of micro plastics in bioaccumulation of organic chemicals to marine aquatic organisms. A critical review --- Nano plastics in the aquatic environment. Critical review --- Part 5 Socio-economic implications of marine anthropogenic litter --- Micro and nano-plastics and human health --- The economics of marine litter --- Regulation and management of marine litter --- Marine litter and the contribution of citizen science
    Pages: Online-Ressource (XVIII, 447 pages) , 68 illustrations, 35 illustrations in color
    ISBN: 9783319165103
    Language: English
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  • 10
    Keywords: Life sciences ; Human physiology ; Food ; Biotechnology ; Microbiology ; Life Sciences ; Food Microbiology ; Food Science ; Human Physiology
    Description / Table of Contents: Introduction --- Gastrointestinal digestion models, general introduction --- Static digestion models general introduction --- InfoGest consensus method --- Approaches to static digestion models --- Dynamic digestion models general introduction --- The TNO gastro-Intestinal Model (TIM) --- Dynamic Gastric Model (DGM) --- Human Gastric Simulator (Riddet model) --- The DIDGI® System --- General introduction to cells, cell lines and cell culture --- Epithelial cell models; General introduction --- Caco-2 cell line --- HT29 cell line --- The IPEC-J2 cell line --- Co-cultivation of Caco-2 and HT-29MT --- Innate and adaptive immune cells; General introduction --- THP-1 and U937 cells --- Peripheral blood mononuclear cells --- PBMC-derived T cells --- Dendritic Cells --- Co-culture Caco-2/ immune cells --- Enteroendocrine Cell Models: General introduction --- STC-1 cells --- NCI-H716 cells --- Murine GLUTag cells --- In vitro intestinal tissue models: General introduction --- Intestinal crypt organoids as experimental models --- Porcine ex vivo intestinal segment model --- Ussing chamber --- In vitro fermentation models: General Introduction --- One compartment fermentation model --- The TNO in vitro model of the colon - TIM-2 --- The Simulator of the Human Intestinal Microbial Ecosystem – SHIME® --- The computer-controlled multicompartmental dynamic model of the gastrointestinal system SIMGI
    Pages: Online-Ressource (XVII, 338 pages) , 57 illustrations, 35 illustrations in color
    ISBN: 9783319161044
    Language: English
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