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  • 1
    Electronic Resource
    Electronic Resource
    Biotechnology in the U.S.S.R. (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 788-788 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Several interesting developments in Soviet biotechnology have been published recently. The All Union Scientific Research Institute of Bioengineering in Moscow has developed an experimental computerized information system called “Ellips-Mikrobiologiiya.” A recent report1 claimed the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0984-788
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  • 2
    Electronic Resource
    Electronic Resource
    New Products (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 813-819 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Ionics, Inc. (Watertown, MA) introduces a recirculating isoelectric focusing system called IsoPrep™. It separates proteins of differing pis on a preparative scale under applied electrical potential. The system's membranes permit convection but let proteins migrate freely until they reach a ...
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    URL: http://dx.doi.org/10.1038/nbt0984-813
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  • 3
    Electronic Resource
    Electronic Resource
    Announcements (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 823-823 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] OCTOBER MEETINGS Oct. 10–11. Robert S. First Conference: The New Microbiology. Washington, B.C. Info: Robert S. First, 707 Westchester Avenue, White Plains, NY 10604 Oct. 11. Today's Profit Opportunities in Biotechnology. Philadelphia, PA. (Also Nov. 15 in Houston, TX.) Info: Consulting ...
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    URL: http://dx.doi.org/10.1038/nbt0984-823
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  • 4
    Electronic Resource
    Electronic Resource
    Chemical and Bacterial Pretreatment of Lignocellulosic Material to Increase Ruminant Digestibility (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 805-807 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A variety of chemical treatments was examined for the ability to decrease the relative lignin content and increase the in vitro dry matter digestibility of peanut hulls. Of these chemical treatments, nitric acid was the most successful at removing lignin; however, none of the chemical treatments ...
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    URL: http://dx.doi.org/10.1038/nbt0984-805
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  • 5
    Electronic Resource
    Electronic Resource
    Nitrogen Fixation in Context (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 821-821 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Fundamentals of Nitrogen Fixation. J. R. Postgate. Pp. 252. ISBN 0-521-24169-3. (Cambridge University Press, Cambridge, England: 1982) $37.50. This modestly-sized volume reminds me favorably of Harris' Nucleus and Cytoplasm, a small but influential book from my past. Like its ...
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    URL: http://dx.doi.org/10.1038/nbt0984-821
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  • 6
    Electronic Resource
    Electronic Resource
    Chemicals from Algae and Plant Tissue (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 665-665 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “Single cell protein J polyhydroxybutyrate not the end of the story.” That forecast was made two years ago by Eric Howells from Id's Corporate Research and Technology Department. The real “end of the story”, he suggested, was the use of stable, safe, versatile microorganisms ...
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    URL: http://dx.doi.org/10.1038/nbt0884-665
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  • 7
    Electronic Resource
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    Restriction Endonuclease Map of pTi Bo542, a Potential Ti Plasmid Vector for Genetic Engineering of Plants (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 702-709 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We report here a physical map of pTi Bo542, a wide-host-range tumor-inducing plasmid of Agrobacterium tumefaciens. Forty-two fragments generated by the restriction endonuclease Bam HI were arranged in a circular array using electrophoretic analysis of clones containing overlapping segments of pTi ...
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    URL: http://dx.doi.org/10.1038/nbt0884-702
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  • 8
    Electronic Resource
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    Bioregulation of Lipid and Protein Synthesis in Soybean by 2-Diethylaminoethyl-3,4-Dichlorophenylether (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 712-714 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Application of the bioregulator 2-diethyla-minoethyl-3,4-dichlorophenylether (DCP-TA) causes significant increases in the lipid (triglyceride) and protein content of the soybean. At the same time, soybean yield is enhanced. No negative relationships among the constituents and yield are observed. ...
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    URL: http://dx.doi.org/10.1038/nbt0884-712
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  • 9
    Electronic Resource
    Electronic Resource
    New Products (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 715-719 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] 1.5 ml micro centrifuge tubes made of high transparency polypropylene and compatible with most centrifuges are available from Tekmar Co. The tubes feature two writing surfaces and are marked at the 1.5, 1.0, 0.5, and 0.1 ml levels. Write in 301 on Reader Service Card. Bio-Rad Laboratories' ...
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    URL: http://dx.doi.org/10.1038/nbt0884-715
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  • 10
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    Agricultural Research and Policy (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 721-721 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Genetic Engineering of Plants. Edited by the Board on Agriculture of the National Research Council. Pp. 96. ISBN 0-309-03434-5. (National Academy Press, Washington, D.C.: 1984) $9.50 In Genetic Engineering of Plants, Leslie Roberts and the staffs of the Council for Research Planning in ...
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    URL: http://dx.doi.org/10.1038/nbt0884-721
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  • 11
    Electronic Resource
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    ‘Gene Machines’ and a New Approach (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 694-695 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Many problems in biotechnology begin with the question “How do we get synthetic DNA in hand?” In the early days of DNA synthesis only a few talented chemists could copy nature in the lab, and no biologist dared request synthetic DNA from these specialists. Nowadays chemical synthesis of ...
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    URL: http://dx.doi.org/10.1038/nbt0884-694
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  • 12
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    Use of a specific Monoclonal Antibody for the Preparation of a Highly Active Immobilized Carboxypeptidase A (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 709-712 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A mouse monoclonal antibody (Ab 100) to carboxypeptidase A (CPA) which binds to the enzyme with a high affinity constant (∼109 M−1) without affecting its catalytic activity was prepared, purified and characterized. Covalent binding of the monoclonal antibody to Eupergit C, or noncovalent ...
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    URL: http://dx.doi.org/10.1038/nbt0884-709
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  • 13
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    Announcements (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 720-720 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SEPTEMBER MEETINGS Sept. 5–7. 6th Australian Biotechnology Conference. Brisbane, Australia. Info: H. W. Doelle, Dept. of Microbiology, University of Queensland, St. Lucia, Qld. 4067, Australia Sept. 9–13. Propogation of Higher Plants Through Tissue Culture III. Knoxville, TN. Info: ...
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    URL: http://dx.doi.org/10.1038/nbt0884-720
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  • 14
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    DNA Probe Rights: A Tangled Web (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 589-590 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK NY—At least three major companies in biotechnology are caught up in the web of patents covering DNA probes—and a complex conflict seems inevitable. Enzo Biochem's non-isotopic DNA probe system, which stains infected cells brown, is used here to detect Chlamydia trachomatis, a ...
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    URL: http://dx.doi.org/10.1038/nbt0784-589
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  • 15
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    Co-Immobilization Speeds Lactose Breakdown (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 594-594 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Another novel approach to the exploitation of cheap and abundant lactose in whey and other wastes was described at Biotech 84 by W. Hartmeier from the Technische Hochschule Aachen in West Germany. Hartmeier reported that co-immobilization of yeast or bacterial cells with ...
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    URL: http://dx.doi.org/10.1038/nbt0784-594
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  • 16
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    Biotech Taking Root in Japanese Agriculture (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 603-603 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TOKYO—The Japanese Ministry of Agriculture, Forestry and Fisheries' new budget for biotechnology has jumped more than 90 percent, to 1.2 billion yen ($5.2 million). This contrasts with a planned 20 percent increase in overall government spending on biotechnology. The Ministry has ...
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    URL: http://dx.doi.org/10.1038/nbt0784-603
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  • 17
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    Formulating a Manufacturing Strategy (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 616-618 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A number of well financed, well managed biotechnology-oriented companies have survived the initial “shakeout” typical of embryonic high technology industries and are at the stage where they have a product or a group of products that are close to commercialization. In some cases, ...
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    URL: http://dx.doi.org/10.1038/nbt0784-616
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  • 18
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    Kidney Plasminogen Activator: A Precursor Form of Human Urokinase With High Fibrin Affinity (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 628-634 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A systematic screen of human kidney tissue samples has resulted in the establishment of a permanent cell line, TCL-598, which produces and secretes into the medium milligrams per liter quantities of a urokinase-like plasminogen activator. Analysis of the properties of this enzyme indicate that it ...
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    URL: http://dx.doi.org/10.1038/nbt0784-628
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  • 19
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    Improvement Of Oligonucleotide-Directed Site-Specific Mutagenesis Using Double-Stranded Plasmid DNA (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 636-639 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Conditions which gave a high yield of oligonucleotide-directed site specific mutagenesis were obtained with use of the lpp gene of Escherichia coli cloned in the versatile expression plasmid vector, pIN-II. This plasmid (5.6-kb) was digested by PstI followed by exonuclease (Klenow fragment of DNA ...
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    URL: http://dx.doi.org/10.1038/nbt0784-636
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  • 20
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    A Little Secrecy Goes a Long Way (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 494-494 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Extensive research and development in other product areas continues at a highly productive pace. Some of this you have heard about, but much you have not. For business and competitive reasons, we have chosen to delay discussing certain products until they are further along the development ...
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    URL: http://dx.doi.org/10.1038/nbt0684-494
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  • 21
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    Flow of Biotech Products Just a Trickle? (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 499-501 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—Is this really the Year of the Product for biotechnology? Much of the press has hailed 1984 as a benchmark year that will see the fruits of biotechnology finally streaming to market. However, most industry analysts view the product flow as nothing more than a promising, ...
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    URL: http://dx.doi.org/10.1038/nbt0684-499
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  • 22
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    The Brazilian National Biotechnology Programme (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 421-431 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Brazil is one of the few third world countries that has a national program for biotechnology. PRONAB (Pro-grama Nacional de Biotechnologia), the Brazilian national biotechnology program, reflects to an extent a recognition that the exploitation of the potential of biotechnology is a matter of ...
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    URL: http://dx.doi.org/10.1038/nbt0584-421
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  • 23
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    U.K. Pushes Downstream Processing Research (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 406-406 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON, England—The government is putting the finishing touches on a massive research program to entice British firms into investing in downstream processing. The program is part of the government's strategy to fill notable gaps in downstream processing skills in British industry. The ...
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    URL: http://dx.doi.org/10.1038/nbt0584-406
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  • 24
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    Oncogenes, Inositol Lipids and Cellular Proliferation (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 541-546 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Cells within the body are normally under careful control to ensure that cell growth occurs only when required either for development or for body maintenance. Quiescent cells can be stimulated to grow by a variety of growth factors which act on cell surface receptors to initiate DNA synthesis ...
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    URL: http://dx.doi.org/10.1038/nbt0684-541
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  • 25
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    Protection of Mice from Lethal Herpes Simplex Virus Infection by Vaccination with a Secreted form of Cloned Glycoprotein D (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 527-532 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Mammalian cell lines have been constructed which synthesize a truncated form of the HSV 1 glycoprotein D (gD). The truncated protein lacks the carboxy-terminal 93 amino acids, is glycosylated, and is constitutively secreted to the culture medium. Radioimmunoprecipitation experiments demonstrate ...
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    URL: http://dx.doi.org/10.1038/nbt0684-527
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  • 26
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    New Technologies for Fermentation, Biological Conversion (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 555-555 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although biotechnology is generally not a theoretical discipline, several researchers discussed important kinetic models. R. D. Tanner (Vanderbilt University, Tennessee) described use of non-constant parameters in the Monod model for growth kinetics. Dynamic phenomena such as hysteresis and ...
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    URL: http://dx.doi.org/10.1038/nbt0684-555a
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  • 27
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    Fermentation Manual Fizzles (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 475-477 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Fermentation and Biochemical Engineering Handbook. Edited by Henry C. Vogel. Pp. 440. ISBN 0-8155-0950-2. (Noyes Publications, Park Ridge, NJ: 1983) $64.00. A handbook, in the sense the editor of this book presumably intended, is meant to be a book of instruction or guidance, a manual for a ...
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    URL: http://dx.doi.org/10.1038/nbt0584-475b
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  • 28
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    Patent Issues Cloud Biotechnology's Future (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 385-387 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—The recent spate of recombinant DNA patent approvals and licensing efforts has both entrepreneurs and lawyers questioning the future of biotech intellectual property. The lingering doubts and controversy surrounding Stanford University's Cohen-Boyer patent (see next page) ...
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    URL: http://dx.doi.org/10.1038/nbt0584-385
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  • 29
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    Construction of a Live Oral Cholera Vaccine (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 334-334 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] One of the great promises offered by recombinant gene technology is the production of new and more effective vaccines1. In this issue of BIO/TECHNOLOGY, James Kaper and his colleagues at the Center for Vaccine Development (CVD, University of Maryland School of Medicine, Baltimore) describe the ...
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    URL: http://dx.doi.org/10.1038/nbt0484-334
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  • 30
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    A Recombinant Live Oral Cholera Vaccine (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 345-349 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A pathogenic strain of Vibrio cholerae was attenuated by deletion of DNA sequences encoding the A1 subunit of the cholera enterotoxin. A restriction endonuclease fragment encoding the A1, but not the A2 or B sequences was deleted in vitro from cloned cholera toxin genes. The mutation was then ...
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    URL: http://dx.doi.org/10.1038/nbt0484-345
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  • 31
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    Energy from Biomass and Wastes (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 434-440 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The effort to develop and apply technology for fuels and energy from biomass and wastes overcame a serious obstacle in 1983—it grew despite reductions in financial support. Presentations at the eighth technical symposium on Energy from Biomass and Wastes, sponsored by the Institute of Gas ...
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    URL: http://dx.doi.org/10.1038/nbt0584-434
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  • 32
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    Novel Bioreactor Systems and Their Applications (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 447-453 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] New sophisticated bioreactor designs with unique performance characteristics will play a vital role in the economic manufacture of useful biotechnological products from natural and genetically modified cell systems of microbial, mammalian and plant origin. In this paper we summarize the basic ...
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    URL: http://dx.doi.org/10.1038/nbt0584-447
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  • 33
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    New Products (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 467-470 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The advent of monoclonal antibody technology opened the way for the expansion of the immunologic products marketplace. A variety of antibodies, antigens, and immunoassay kits and equipment are available to simplify procedures in the immunology laboratory. For example, Molecular Genetics Inc. has ...
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    URL: http://dx.doi.org/10.1038/nbt0584-467
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  • 34
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    Flourishing Not Easy, German Company Finds (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 292-296 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HAMBURG, West Germany—Despite their government's declared commitment to biotechnology (See page 291), German scientists who would like to be commercial biotechnologists have found the road to starting a company strewn with obstacles. Take Biosyntech, for example. Hubert Koester of the ...
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    Japan Taps into New Biotech (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 307-321 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The Japanese people have long been noted for their ability toassimilate features of other cul-tures to support their island existence. Their language, their chief religions, many of their arts, and the major new technologies of this century have been freely adapted from other cultures to enable a ...
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    Biotechnology Trade with Japan (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 327-332 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Trade in biotechnology products is just beginning as the products start to reach the international marketplace. Even firms not planning to manufacture and market specific products should consider foreign markets for biotechnology products, and the Japanese market certainly will be a key factor in ...
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    Industry should Collaborate on Scale up Problems (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 109-109 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although the laboratory end of biotechnology's stream of development enjoys the lion's share of attention, the scale-up stage of process development determines the feasibility of actually manufacturing a product. The sheer cost in time, equipment, and labor of scaling up presents a roadblock to the ...
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    Researchers Seeking New Uses for Lignin (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 111-112 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] GOLDEN, Colorado—New applications are in the works for lignin, the major phenolic component of wood that is most difficult to convert into useful and valuable products, according to a report that the Solar Energy Research Institute (SERI), located here, plans to issue this spring. Industrial ...
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    Tech Brokers Focus on Japan Biotech Transfer (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 115-116 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—The techniques of biotechnology have become sufficiently valuable world commodities that a few companies now focus on selling them, particularly to Japan and the Far East. While U.S. computer and semiconductor industries have found that reaping the short-term financial ...
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    Oncogene Science Completes Private Stock Offering, Begins Operations (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 118-123 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MINEOLA, New York—Oncogene Science, Inc., long rumored to be in the works, has begun research in cancer diagnostics and therapeutics here, 10 miles from the famous research laboratory at Cold Spring Harbor (CSH). Although Oncogene Science (OSI) has no official connection with GSH, a number of ...
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    Copyrightability of Genetic Works (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 138-142 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Legal protection for the intellectual property of industrial and academic genetic engineering laboratories has acquired paramount importance in the last few years. Traditionally, there have been three basic forms of protection: patents, trade secrets, and private contracts. One or more of these, ...
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    Liposomes in Medicine: A 15 Year Retrospective (1984)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 2 (1984), S. 146-147 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A conference titled The Use of Liposomes in Medicine, held in honor of Brenda E. Ryman on her retirement from Charing Cross Hospital Medical School (London, U.K.), offered a forum for liposome researchers to present their latest results, but it also provided a fitting occasion to reflect on the ...
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    Enhancers and other Regulators of Eukaryotic Gene Expression: A First Account (1984)
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    Nature biotechnology 2 (1984), S. 173-173 
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    Notes: [Auszug] Enhancers and Eukaryotic Gene Expression. Edited by Yakov Gluzman and Thomas Shenk. Pp. 218. ISBN 0-87969-161-1. (Current Communications in Molecular Biology, Cold Spring Harbor Laboratory: 1983) $27.00. In multicellular organisms, different sets of genes are switched on in different ...
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    The Age of Genetic Engineering (1984)
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    Nature biotechnology 2 (1984), S. 173-174 
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    Notes: [Auszug] The Gene Age. By Edward J. Sylvester and Lynn C. Klotz. Pp. 208. ISBN 0-684-17950-4 (Charles Scribner's Sons, New York: 1983) $14.95. The Gene Age is an excellent one-stop review of the controversies and some of the promises brought on by the advent of genetic engineering. The text is ...
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    International Patents (1984)
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    Nature biotechnology 2 (1984), S. 182-183 
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    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Title: Genes and DNA Transfer Vectors for Prorelaxin Expression Inventors: P. J. Hudson, J. D. Haley, H. D. Niall, and J. Shine, Australia Assignee: Howard-Florey Institute of Experimental Physiology and Medicine, Australia Filing and Issue Data EPO Patent No.: 86-649 Publication Date: 24 ...
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    Do We Need a Special Patent Law for Biological Inventions? (1984)
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    Nature biotechnology 2 (1984), S. 192-192 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In 1980 the U.S. Supreme Court held, 5–4, that a living organism could be patented as a “manufacture” or “composition of matter” if it satisfied the other requirements of the patent laws. While this decision was a milestone for the biotechnology industry, it should not ...
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    Reports of its Death were Exaggerated (1984)
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    Nature biotechnology 2 (1984), S. 1005-1005 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] To the editor: I am writing in reference to your article entitled “Phillips: Wildcatting in Biotech” (BIO/TECHNOLOGY 2:853, 1984). The article implied that the Bartlesville Energy Technology Center (BETC), including its capabilities in microbial enhanced oil recovery, is now defunct. I ...
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    Reply to : The Dangers of Nitro Compounds (1984)
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    Nature biotechnology 2 (1984), S. 1005-1005 
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    Notes: [Auszug] We would like to state the following in reply to Dr. Brind's letter concerning the possibility of passing on carcinogenic nitro-compounds to consumers of beef or milk from cattle that have been fed peanut hulls treated with nitric acid and the bacterium Arthrobacter sp. KB-1. After the hulls are ...
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    Firms Seek to Score on Protein Analysis (1984)
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    Nature biotechnology 2 (1984), S. 1011-1012 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] ROCKVILLE, Md.—Two new companies are seeking to commercialize 2-dimensional gel electrophoresis, a separations technology that has existed for close to a decade. Bioresources Laboratories, the for-profit company started here by the American Type Culture Collection (ATCC) a year-and-a-half ...
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    Characterization Studies on Human Melanoma Cell Tissue Plasminogen Activator (1984)
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    Nature biotechnology 2 (1984), S. 1051-1057 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Purified tissue plasminogen activator synthesized by a human melanoma cell line has been partially characterized. On SDS gel electrophoresis, the purified samples exhibited a doublet at molecular weights 63,000 and 65,000. Staphylococcal V8 proteolytic digestion of the separated species yielded ...
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    Celltech, Sankyo Agree on Anti-Tumor Agents (1984)
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    Nature biotechnology 2 (1984), S. 1021-1021 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—Celltech, Ltd., has signed a development agreement with the Japanese company Sankyo in respect of two anti-tumor agents which could be marketed by the end of this decade. The two agents are human macrophage activating factor (MAF) and tumor necrosis factor (TNF), both of which also ...
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    Chromatographic Removal of Pyrogens (1984)
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    Nature biotechnology 2 (1984), S. 1035-1038 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Endotoxins are toxic lipopoly-saccharides that are released from the cell wall of gram negative bacteria upon cytolysis. Endotoxins are pyrogenic, that is, they produce a rise in temperature in man or other mammals. Even if the bacteria are killed, the endotoxins remain pyrogenic and thus their ...
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    New Uses for Synthesis Gas (1984)
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    Nature biotechnology 2 (1984), S. 935-935 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] MUNICH—There are many exciting opportunities for biological processing of the “synthesis gas” produced by coal gasification, according to a paper presented at the Third European Congress of Biotechnology by J. Colby from Sunderland Polytechnic and colleagues at the University of ...
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    A Novel Method of Immobilization and its Use in Aspartic Acid Production (1984)
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    Nature biotechnology 2 (1984), S. 1081-1084 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Escherichia coli, having high aspartase activity, were immobilized by covalent attachment and entrapment with polyazetidine with .retention of 97% of the free cell activity. The projected enzyme half-life was 611 days. Stability of the system was greater than 2 years at 25°C without loss of ...
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    Announcements (1984)
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    Nature biotechnology 2 (1984), S. 1089-1089 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] JANUARY MEETINGS Jan. 26–Feb. 2. UCLA Symposium on Monoclonal Antibodies and Cancer Therapy. Park City, UT. Info: Betty Handy, Program Coordinator, UCLA Symposia, Molecular Biology Institute, University of California, Los Angeles, CA 90024 Jan. 28–Feb. 1. 9th Annual Symposium on ...
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    Hype, Hope and Honesty (1984)
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    Nature biotechnology 2 (1984), S. 1096-1096 
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    Notes: [Auszug] Over the last few years I believe that there has been a disturbing trend in the way in which discoveries in fundamental cancer research are reported, giving the general public an unrealistic picture of the time needed to convert today's discoveries into effective treatments. The public, ...
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    Molecular Biology and Ecology of Diazotrophs Associated with Non-Leguminous Plants (1984)
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    Nature biotechnology 2 (1984), S. 967-978 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Only some prokaryotes have evolved the genetic information for nitrogen fixation. These prokaryotes, when associated with plants, can contribute to their growth by providing reduced nitrogen (ammonia). The genetics of nitrogen fixation was elucidated in Klebsietta pneumoniae, where it was found ...
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    Confronting the Genetic Era (1984)
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    Nature biotechnology 2 (1984), S. 991-991 
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    Notes: [Auszug] Biofuture: Confronting the Genetic Era. By Burke K. Zimmerman. Pp 305. ISBN 0-306-41315-9. (Plenum Press, New York and London: 1984) $16.95. Biofuture is the best book yet on the scientific, moral, and policy implications of the new genetics. This is largely because Burke Zimmerman has a ...
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    New Images for Old (1984)
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    Nature biotechnology 2 (1984), S. 837-837 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Should we reassess our metaphors for biotechnology? Metaphor, simile, analogy, synecdoche, metonymy: the arsenal of rhetoric overflows with tricks for saying one thing by talking about something else entirely. We seek out parallels, the likeness that makes the unfamiliar seem familiar, that lets us ...
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    A Polypeptide Fusion Designed for the Purification of Recombinant Proteins (1984)
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    Nature biotechnology 2 (1984), S. 76-81 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Recombinant DNA technology was used to produce human urogastrone with a C-terminal polyarginine fusion. This peptide fusion formed the basis of a two-step ion exchange purification that gave 64mg of urogastrone at 〉95% purity with 44% yield. In the first step, a substantial purification was ...
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    Chronicle (1984)
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    Nature biotechnology 2 (1984), S. 849-849 
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    Notes: [Auszug] At presstime, University Genetics' president, Alan G. Walton, reported that UGEN will acquire only 55 percent of Trans World Genetics, instead of the 90 percent reported in a news story in this issue. Walton said UGEN has set up a new 100 percent-owned subsidiary, Applied Animal Genetics (Napa, ...
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    Novel High-level Expression Cloning Vehicles: 10 4 -fold Amplification of Escherichia coli Minor Protein (1984)
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    Nature biotechnology 2 (1984), S. 81-85 
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    Notes: [Auszug] Versatile, high-level expression cloning vehicles, pINIII, have been constructed. A foreign DNA fragment can be inserted in any one of the three reading frames at the unique EcoRI, HindIII, or BamHI site immediately after the initiation codon. The cloned foreign gene is under the control of both ...
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    Announcements (1984)
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    Nature biotechnology 2 (1984), S. 91-92 
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    Notes: [Auszug] JANUARY MEETINGS Jan. 8–10. Fourth Conference on Human Tumor Cloning. Tucson, AZ. Info: Mary Humphrey, Conference Coordinator, University of Arizona Cancer Center, Tucson, AZ 85724 Jan. 9–14. The Eleventh Aharon Kat-zir-Katchalsky Conference: Plant Molecular Biology. Jerusalem, ...
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    Should Lactic Acid Bacteria Be Engineered? (1983)
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    Nature biotechnology 1 (1983), S. 728-729 
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    Notes: [Auszug] WAGENINGEN, Netherlands—An international committee is needed to consider safety and public acceptance of microorganisms used in food production, especially any that are genetically engineered, according to A.J. Sinskey, Massachusetts Institute of Technology (Cambridge). The committee should ...
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    Celebrating the Double Helix (1983)
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    Nature biotechnology 1 (1983), S. 731-731 
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    Notes: [Auszug] BOSTON, Massachusetts—Francis Crick and James Watson blended anecdote with science when they joined together here in September at a conference celebrating their discovery of DNA's structure more than 30 years ago. They also revealed what may have been the meeting's most intriguing news: a ...
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    French Science Salutes Biotechnology (1983)
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    Nature biotechnology 1 (1983), S. 732-732 
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    Notes: [Auszug] PARIS, France—The French government and scientific establishment joined forces to demonstrate France's commitment to biotechnology by co-sponsoring a week-long biotech exposition here in September, under the aegis of the Institut Pasteur and the Ministry of Industry and Research. The ...
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    Australia Ups Biotech Support (1983)
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    Nature biotechnology 1 (1983), S. 735-735 
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    Notes: [Auszug] CANBERRA, Australia—The Australian government has increased its financial support for biotechnology significantly in the past few weeks. The package includes a substantial budget for R&D as well as incentives to encourage private investment in biotech. The government has recommended a ...
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    Emerging Roles Of NIH And EPA in the Regulation Of rDNA Technology (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 757-768 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The question of the extent to which the recombinant DNA (rDNA) technology should be regulated, if at all, has been grappled with since 1974 when a moratorium was called on certain experiments while questions of public safety were further evaluated1. Since then, rDNA research has been regulated by ...
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    New Hopes for Bacteriophage Therapy (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 777-777 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Do you mean to say you think you've discovered an infectious disease of bacteria, and you haven't told me about it?” the chief asks young Martin Arrowsmith in Sinclair Lewis's masterly, microbiological novel of that name. “My dear boy, I don't believe you quite realise you may have hit ...
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    Direct Demonstration of Lactate–Acrylate Interconversion in Clostridium Propionicum (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 791-794 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We present evidence that acrylate is an intermediate in the direct reduction of lactate to propionate in Clostridium propionicum. In the presence of 3–butynoic acid, an inhibitor of acyl–CoA dehydrogenase, acrylate was formed from D–lactate and detected by gas–liquid ...
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    Cycloheximide Induction of Aflatoxin Synthesis in a Nontoxigenic Strain of Aspergillus Flavus (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 794-795 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The biogenetic basis of aflatoxin production was investigated by testing the influence of known inhibitors of protein synthesis on several toxigenic and nontoxigenic strains of Aspergillus flavus and Aspergillus parasiticus. Cycloheximide induced significant synthesis of aflatoxin B1 and aflatoxin ...
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    Eukaryotic Vectors (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 801-803 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TITIE: Control of DNA Sequence Transcription INVENTORS: Richard D. Palmiter, Seattle, WA, and Ralph L. Brinster, Gladwyne, PA, U.S. ASSIGNEE: University Patents, Inc., Norwalk, CT, U.S. FILING AND ISSUING DATA: PCT Publication No.: WO83/01783 PCT Publication Date: 26 May 1983 Priority ...
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    Budapest Treaty Makes Biotechnology Patenting Simpler (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 801-801 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Although a written description may fill the disclosure requirement for a patent for mechanical, electrical, or chemical inventions, biotechnology inventions require a publicly available microorganism deposit to fill this requirement. Internationally minded corporations that file biotechnology ...
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    The Need for New Project Review Systems (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 814-814 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Commercial developers and biologists need to form useful relationships and address the issues that are fundamental to the development of biotechnology businesses. For example, how do worthy scientific projects find worthy backers? How will the scientific merit of a new enterprise be determined? Who ...
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    Consider Biotech's Foreign Policy Potential (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 637-637 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biotechnology is destined to become a tool of ever increasing importance in foreign aid policy, especially in light of important socioeconomic characteristics of its use: successful development of the technologies can have immediate and multiple effects on the economy. Use of the new technologies ...
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    Industry Scientists' Salaries Stabilizing in U.S. as Competition Heats Up (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 641-645 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—A pattern for American biotechnology company salaries is beginning to emerge after a five-year period in which industry was forced by the low-supply/high-demand marketplace to pay more to attract good scientific talent. An informal BIO/TECHNOLOGY survey of a dozen U.S. ...
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    Harvesting Profitable Products from Plant Tissue Culture (1983)
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    Nature biotechnology 1 (1983), S. 649-659 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Plants and biotechnology. The phrase suggests agricultural genetic engineering feats like giving non-leguminous plants the ability to fix nitrogen, or conferring herbicide resistance on crops. Yet plant biotechnology's first commercial success may lie elsewhere, because plants serve not only as ...
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    Correspondence (1983)
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    Nature biotechnology 1 (1983), S. 675-675 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: In his column, “Regulatory Trends for Biotechnology Products” [BIO/TECHNOLOGY, 1983, 1:240–246], Dr. E. Korwek has misrepresented the sense and substance of the FDA's position on pharmaceuticals produced using recombinant DNA techniques. He takes the FDA to task ...
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    Characterization and Properties of Cellulases Purified from Trichoderma Reesei Strain L27 (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 687-690 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Trichoderma reesei strain L27 produces multiple 1,4–β–D–glucan cellobiohydrolases, endo–1,4–β–D–glucanases, and 1,4–β–D–glucosidases. The major cellobiohydrolase (CBHI) and endoglucanase (EGI) have been purified to ...
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    Biotechnology Scarce at Food Congress (1983)
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    Nature biotechnology 1 (1983), S. 729-729 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] DUBLIN, Ireland—Biotechnology is important to the food industry, the experts say, but it was not much in evidence at the Sixth World Congress of Food Science and Technology, which attracted nearly 1000 participants here in September. Only one of the 20 scheduled sessions was devoted to ...
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    Patent Cooperation Treaty May Not Benefit Biotechnology (1983)
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    Nature biotechnology 1 (1983), S. 709-709 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Patent Cooperation Treaty, or PCT, gives inventors the option of reserving patent protection in 32 additional countries at the same time that they file in the U.S. Thirty-three countries ratified the 1978 treaty, under which a patent filed in one country forms the basis for protection in all ...
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    Celltech Opens New Monoclonal Production Facility (1983)
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    Nature biotechnology 1 (1983), S. 534-536 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SLOUGH, England—Britain's partly state-owned medical biotechnology company, Celltech, has established what it claims is the world's largest production facility for monoclonal antibodies. At its headquarters here, near London, the company has just completed a tissue culture development ...
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    New York, New Jersey Can Support Biotech, Study Claims (1983)
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    Nature biotechnology 1 (1983), S. 538-541 
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    Notes: [Auszug] NEW YORK, New York—The New York/New Jersey metropolitan region has all the necessary ingredients to support a growing biotechnology industry. So says a new report co-sponsored by an unusual consortium composed of New York State, New York City, the state of New Jersey, the Port Authority (a ...
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    New Trends in Financing Biotechnology (1983)
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    Nature biotechnology 1 (1983), S. 544-559 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Some 200 biotechnology companies have come into existence, most within the last four years. For all of these companies, new capital is the key to survival, especially if the industry shake-out Wall Street analysts have predicted comes to pass. So it is hardly surprising that there has been a flurry ...
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    Biotechnology in Europe: The Structure of an Industry (1983)
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    Nature biotechnology 1 (1983), S. 561-565 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Repeat an assumption often enough and it risks entering the folklore as an accepted fact. Just such a situation surrounds much of the European biotechnology industry, particularly that segment involved in pharmaceutical production. For years it has been said that European industry has a massive ...
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    Bacteria Living at 350°C May Have Industrial Uses (1983)
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    Nature biotechnology 1 (1983), S. 640-641 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SHADYSIDE, Maryland—Scientists are wondering whether bacteria living in 350°C deep-sea hot vents may have important industrial applications. These extreme thermophiles were recently cultured and partly characterized by John A. Baross of Oregon State University's School of Oceanography ...
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    Public says Genetic Engineers Should Proceed Cautiously (1983)
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    Nature biotechnology 1 (1983), S. 645-646 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK, New York—Nearly two-thirds of the American people appear to believe society should exercise caution in proceeding with genetic engineering, and almost a third of them are worried that genetic engineering may result in more harm than benefit. These negative feelings about genetic ...
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    Genetic Engineering and Environmental Pollution: Potential and Uncertainties (1983)
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    Nature biotechnology 1 (1983), S. 670-673 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The use of genetically engineered microorganisms for I controlling man-made pollutants is an enticing proposition. Microbes degrade a host of different molecular structures in nature, so why not enhance this capability? Furthermore, it may be possible to develop organisms with traits not found ...
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    Biotechnology in Utilization of Wood (1983)
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    Nature biotechnology 1 (1983), S. 666-668 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Even though wood is the world's most abundant renewable organic material, biotechnology plays only a minor role in its utilization. Some conventional fermentation of sugar-rich pulping waste streams is practiced, standard biological waste treatments are employed by wood-using industries, and ...
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    Two Phase Systems for Biotechnological Isolations (1983)
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    Nature biotechnology 1 (1983), S. 668-669 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] One of the problems most frequently encountered in large-scale biotechnological production methodologies is the isolation of the species of interest from complex mixtures of degradative enzymes, proteins, nucleic acids, and cellular debris. On the one hand, the scale of the procedures and the need ...
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    Molecular Cloning of Exo–Cellobiohydrolase I Derived from Trichoderma Reesei Strain L27 (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 691-696 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The molecular cloning and characterization of the gene encoding exo–cellobiohydrolase I (CBHI) of Trichoderma reesei strain L27 is reported. Two adjacent HindIII genomic fragments of 1.16 kb and 2.3 kb were identified using differential hybridization techniques and were sub–cloned into ...
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    Biochemical Handbook (1983)
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    Nature biotechnology 1 (1983), S. 701-702 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Biochemical Engineering and Biotechnology Handbook. Edited by Bernard Aikens and Ferda Mavituna. Pp. 1119. ISBN 0 333 332741 (The Nature Press: New York). $97.00 The authors have assembled an impressive array of information, undoubtedly useful to workers in the field. The book is divided ...
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    Toward a National Policy on Human Genetic Engineering (1983)
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    Nature biotechnology 1 (1983), S. 718-718 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The House of Representatives currently has before it legislation that could help direct the development of future public policy on biotechnology in this country. The legislation, which I introduced this past spring, establishes the President's Commission on the Human Applications of Genetic ...
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    Boom Days for Biotech—With a Word of Caution (1983)
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    Nature biotechnology 1 (1983), S. 533-533 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The infusion of capital into biotechnology over the past twelve months is a welcome sign for anybody involved in this area of R&D. As this month's feature on new sources of international finance indicates, there is renewed confidence in the profitability of biotech research; in the U.S., at ...
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    The Bio/Technology Index of Specialty Firms (1983)
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    Nature biotechnology 1 (1983), S. 536-536 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Many of our readers interested in biotechnology want to follow the stock prices of biotechnology companies, although there does not seem to be a way to clearly define the status of that mythical animal called the biotechnology company. In fact, there are no biotechnology companies in the strict ...
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    Human MCA Against Colon Cancer Produced At Litton (1983)
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    Nature biotechnology 1 (1983), S. 537-538 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] KENSINGTON, Maryland—A technique for producing human monoclonal antibodies directed against tumor antigens associated with human colorectal cancers has been developed at Litton Bionetics, which says it has produced more than 20 of these cancer-reactive monoclonals since the beginning of the ...
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    Enzymes To Order: Researchers Report Progress (1983)
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    Nature biotechnology 1 (1983), S. 541-543 
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    Notes: [Auszug] CAMBRIDGE, England—Tell us what chemical reaction you want performed and we can build an enzyme to catalyze it. That was the confident message emerging from a symposium on the application of recombinant DNA technology to enzymology, held here by the Biochemical Society at the end of June. To ...
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    Good News From NSF for Research (1983)
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    Nature biotechnology 1 (1983), S. 533-533 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The National Science Foundation (NSF) enters fiscal year 1984 with a healthy 21 percent budget increase. This increase, which will provide a $31.4 million boost to the current bioscience research budget of approximately $145.5 million, will certainly benefit biotechnology. NSF ...
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    Characterization of Two Cel (Cellulose Degradation) Genes of Clostridium Thermocellum Coding for Endoglucanases (1983)
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    Nature biotechnology 1 (1983), S. 589-594 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Two structural genes, celA and celB, coding respectively for the endoglucanases A and B of Clostridium thermocellum, were subcloned from cosmids of a gene bank into plasmid pBR322. Both genes are carried in a DNA sequence of about 2.7 kb. They share no homology and are not contiguous on the C. ...
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    Electrofusion: A Faster, More Efficient Technique for Hybridoma Production (1983)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 1 (1983), S. 390-391 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] JÜLICH, West Germany—The Nuclear Research Center, Kernfors-chungsanlage (KFA), announced new licensing agreements for the international manufacturing and marketing of equipment for electro fusion, an efficient new process that uses electric fields to fuse cells. Kruess GmbH of Hamburg ...
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