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  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry  (173)
  • IntechOpen  (173)
  • Essen : Verl. Glückauf
  • Krefeld : Geologischer Dienst Nordhein-Westfalen
  • English  (173)
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  • English  (173)
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  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: In recent years, great progress has been made in the field of essential oils as scientific research has revealed new insights into the biological benefits, healing properties, and other uses. Interest in their use in various industries, such as medicine, agriculture, food, and cosmetics, has increased. Essential oils have found their place in many applications, thus fueling a wave of scientific research and industrial applications. This book explores these recent developments in detail, revealing new perspectives and applications of essential oils. It combines historical knowledge with the latest research to provide a comprehensive overview of the field. By exploring the ancient legacy of aromatic plants and their traditional medicinal uses, as well as delving into the latest research and industrial applications, this book provides a comprehensive understanding of essential oils and their potential.
    Keywords: thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Vitamin B is a water-soluble vitamin that plays important roles in cell metabolism and synthesis of red blood cells. Many foods contain B vitamins, including meat, poultry, and fish, among others. Vitamin E is a fat-soluble vitamin with antioxidant properties that can be found in vegetable oils, cereals, meat, poultry, eggs, and fruits. Both vitamins B and E are important for human health. This book provides a comprehensive overview of vitamins B and E. It is organized into three sections on the role of vitamin B on body health and gut flora, vitamin B deficiency and its association with the disease pellagra, and the medicinal significance and complications associated with vitamin E deficiency.
    Keywords: thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Amino Acid - New Insights and Roles in Plant and Animal provides useful information on new aspects of amino acid structure, synthesis reactions, dietary application in animals, and metabolism in plants. Section 1 includes chapters that describe the therapeutic uses, antiallergic effects, new aspects in the D-amino acid structure, historical background of desmosines, and stereoselective synthesis of ?-aminophosphonic acids. Section 2 presents the role of amino acids in plants, which includes new insights and aspects of D-amino acids, metabolism and transport in soybean, changes during energy storage compound accumulation of microalgae, and determination of amino acids from natural compounds. Section 3 describes the chapters on methodologies and requirement of dietary amino acids for Japanese quails, laying hens, and finishing pigs. The final chapter identifies potential importance of glutathione S-transferase activity for generating resistance to triclabendazole in Fasciola hepatica.
    Keywords: amino acids, biomarkers, bacteria, microalgae, phytochemicals, physiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Lactation is a fascinating process. Research over the last decade has provided new insights into the regulation of mammary gland development and involution. Lactation is the last step in reproduction, and therefore it is linked to reproduction strategy. Photoperiod species such as sheep, or pseudo-ovulatory (at mid-gestation) species as the rodent Lagostomus maximus, are interesting and unique models to study mammary gland physiology. This book also offers updated insights into the mechanisms that control postlactational involution, therefore also providing information to better understand breast cancer. Small noncoding RNA has opened new understanding in gene regulation. In this regard, our knowledge of mammary gland development and milk secretion has increased extremely. This book provides current scientific information on all these interesting topics. It will certainly be of great benefit to those interested in biomedical sciences.
    Keywords: mammary gland, breast cancer, microrna, melatonin, genome editing, cell death ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Chlorophyll, a green pigment present in almost all plants, algae, and cyanobacteria, is a significant biomolecule essential to photosynthesis, the process by which plants convert light into energy. This book provides a comprehensive and easy-to-understand source of information on the latest developments in chlorophyll research. It is a collection of contributions from leading specialists in the subject. Topics discussed include the medicinal uses of chlorophyll, the electronic structure of chlorophyll monomers and oligomers, and chlorophyll estimate from fluorescence vertical profiles in the ocean.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Proteomics Technologies and Applications reviews and describes the nature and application of molecules with proteins or peptides, and elucidates and predicts the possible molecular and physiological causes related to changing proteomic profiles. Chapters target various methods and tools available for analysis, detection, separation, quantification, and localization of cell proteomes of a biological system, which are helpful as biomarkers for various disease prognoses and diagnoses.
    Keywords: mass spectrometry, biomarkers, breast cancer, colorectal cancer, melanoma, glioblastoma ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Carotenoids are one of the most widespread pigment groups distributed in nature; more than 700 natural carotenoids have been described so far. These pigments are known for versatile roles they play in living organisms; however, their most pivotal function is involvement in scavenging of reactive oxygen species and photoprotection. In the same time, carotenoids as natural pigments with important biological activities, such as antioxidant and provitamin A activity, have a great potential in the food, feed and pharmaceutical industries. They can be either extracted from plants and algae or synthesized by various microorganisms, including bacteria, yeasts, filamentous fungi and microalgae.
    Keywords: β-carotene, antioxidants, toxicity, cardiovascular disease, stress, microalgae ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The book A Critical Evaluation of Vitamin D - Basic Overview targets the physiological, biochemical and immunological aspects of vitamin D, including principles, mechanisms and clinical significance. This book covers four sections: ‘Vitamin D on Physical and Physiological Activities’, ‘Vitamin D on Biochemical and Immunological Activities’, ‘Vitamin D on Musculoskeletal and Neurological System’ and ‘Vitamin D on Reproductive System’. Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to students, scientists, physicians, healthcare professionals and also other members of this society who are interested in exploring the role of vitamin D in human life. We derive vitamin D from the sunshine, and hence it can also be considered as ‘day’ vitamin.
    Keywords: osteoporosis, vitamin d deficiency, cancer, inflammation, oxidative stress, biomarkers ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Modern medicine is impossible without antibiotics, but global antibiotic usage has led to the development of increasing numbers of multi-drug resistant (MDR) bacteria. Thus, we still have problems with infectious disease treatment despite an arsenal of antibiotics. This has forced researchers to develop new drugs that will be effective against resistant bacteria. Some of these prospective molecules are antimicrobial peptides (AMPs), which are an important component of the innate immune system of various organisms in nature. Currently, more than 3,000 AMPs have been reported with different activities against different bacterial species including resistant phenotype bacteria. AMPs display remarkable structural and functional diversity that is not completely understood. As such, this book presents a comprehensive overview of AMPs and their mechanism of action against MDR bacteria.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Metabolomics is the methodology and theory to study the metabolome, including targeted approaches based on selected/multiple reaction monitoring (SRM/MRM) and untargeted approaches based on nuclear magnetic resonance (NMR) or mass spectrometry (MS). The metabolome contains all metabolites derived from sugars, lipids, proteins, and nucleic acids in a given biological system, tissue, cell, or body fluid in a metabolic network system. Metabolomic variations directly link to molecular mechanisms of a disease, reliable therapeutic targets, and effective biomarkers for prediction, diagnosis, and prognostic assessment of disease. This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.
    Keywords: biomarkers, drug discovery, metabolites, personalized medicine, transgenic plant, fungus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 11
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Oxidative stress is a major contributor to the etiology of chronic disorders like cancer, diabetes, neurodegenerative diseases, and cardiovascular diseases. Long-term exposure to elevated levels of pro-oxidant substances can lead to structural damage in mitochondrial DNA as well as functional changes in a number of enzymes and cellular components, which can lead to abnormalities in gene expression. Modern lifestyles, which include eating processed food, exposure to a variety of chemicals, and not exercising, are significant factors in the development of oxidative stress. However, the ability of medicinal plants with antioxidant capabilities to cure or prevent a number of human illnesses in which oxidative stress appears to be a contributing factor has been demonstrated. A growing body of research links free radicals to the etiology of many diseases, supporting the use of antioxidants as a promising therapeutic strategy for the management of pathologies caused by free radicals. Despite these remarkable advances, there is still much to learn about the relationship between free radicals and antioxidants. Understanding the principles behind pathological and physiological disorders caused by free radicals is crucial. Importance of Oxidative Stress and Antioxidant System in Health and Disease contributes to understanding the fundamental principles of oxidative stress and the effects of antioxidants on disease and health.
    Keywords: reactive oxygen species ; antioxidants ; cardiovascular disease ; phytochemicals ; drug resistance ; infertility ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 12
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Vitamin E is a group of fat-soluble compounds found in a wide variety of foods. Daily requirements of vitamin E can be met with a balanced diet. High-dose supplementation may be hazardous rather than beneficial. Vitamin E serves as an antioxidant, participates in anti-inflammatory processes, inhibits platelet aggregation, and enhances immunity. Vitamin E supplementation can be beneficial against coronary artery disease, eye disorders, cognitive decline, cancer, and skin aging. This book will mainly focus on the diverse functions of vitamin E, importance of vitamin E status to provide a healthy lifespan, and the interaction between vitamin E and several pathological conditions. Readers will receive a general overview of the importance of vitamin E in health and different pathological conditions.
    Keywords: oxidative stress, antioxidants, pregnancy, nutrition, medicinal plants, reactive oxygen species ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Soybean is an agricultural crop of tremendous economic importance. Soybean and food items derived from it form dietary components of numerous people, especially those living in the Orient. The health benefits of soybean have attracted the attention of nutritionists as well as common people.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The book, which is related to QSAR in sciences, is divided into five main chapters. The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of peptidic inhibitors that possessed a substrate transition-state analog and evaluating the structure-activity relationship of the designed inhibitors, based on docking and scoring, using the docking simulation software Molecular Operating Environment. The aim of the forth chapter is to develop structure-property relationships for the qualitative and quantitative prediction of the reverse-phase liquid chromatographic retention times of chlorogenic acids. The final chapter aims to determine the model of interactions between the natural compounds with anti-inflammatory molecular target by molecular docking analysis.
    Keywords: alzheimer’s disease, molecular dynamics, anti-inflammatory, fractal dimension, natural compounds, coffee ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Superfoods and functional foods are receiving increasing attention because of their important roles in health. This book focuses on the production of superfoods and functional foods and their role as medicine. In the early chapters, prominent researchers introduce the roles and production of microalgae and functional fruits through metabolic engineering, the use of food waste, and effective cooking procedures. In the latter chapters, other prominent researchers introduce the medical effects of polyphenols, glutamine, and unsaturated fatty acids, which are contained in superfoods and functional foods. They suggest the importance of superfoods and functional foods in the treatment and prevention of many diseases. It is also recommended for readers to take a look at a related book, Superfood and Functional Food: An Overview of Their Processing and Utilization.
    Keywords: cancer, bioactive compounds, microalgae, biotechnology, cardiovascular diseases, functional foods ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Vitamin D, a fat-soluble vitamin, also called as "sunshine vitamin" is derived mostly from sun exposure and food, and for normal activation, it has to undergo two hydroxylation reactions. Vitamin D affects more than 2000 genes in the body. Serum level of 25(OH) D is an ideal indicator of vitamin D status in our body. Vitamin D deficiency leads to various diseases. On a therapeutic point of view, vitamin D helps to treat many diseases. The book "A Critical Evaluation of Vitamin D - Clinical Overview" targets the principles, mechanisms, and clinical significance of vitamin D. This book covers four sections: "Vitamin D in Cardiovascular and Renal Diseases", "Vitamin D in Age and Neurological Diseases", "Vitamin D and Cancer" and "Therapeutic Measurements of Vitamin D". Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to students, scientists, physicians, healthcare professionals and also other members of this society who are interested in exploring the role of vitamin D in human life. [Vitamin D can be considered as vitamin of "defense" since it cures several diseases. - Sivakumar Gowder]
    Keywords: chronic kidney disease, vitamin d deficiency, breast cancer, nanoparticles, alzheimer’s disease, cardiovascular disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: From time immemorial fermented foods have undoubtedly contributed to the progress of modern societies. Historically, ferments have been present in virtually all human cultures worldwide, and nowadays natives from many ancient cultures still conduct a wide variety of food fermentations using deep-rooted recipes and processes. Within the last four centuries, scientific research has started to unravel many aspects of the biological process behind fermentations, which has contributed to the improvement of many industrial processes. During our journey in the research field, we have always been attracted to the development of scientific research around fermentations, especially autochthonous ferments: a natural repository of novel biomolecules and biological processes that will positively impact on many application fields from health, to food, to materials.
    Keywords: nutrition, fermentation, fluorescence, probiotics, antioxidant activity, phenolic compounds ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Kinetics of Enzymatic Synthesis gives insight into different aspects of chemical reactions that are catalyzed by enzymes. This book is divided into two sections: "Enzyme Kinetics" and "Enzymatic Synthesis". The first section consists of two chapters with a halophilic enzyme kinetics and thermodynamic approach towards analyzing the influence of co-solvents on the Michaelis constants of enzyme-catalyzed reactions. The second section consists of three chapters. Production of isoamyl acetate using the enzymatic synthesis method between acetic anhydride and isoamyl alcohol by having enzyme Candida antarctica Lipase B as catalyst in a solvent-free system is discussed in the third chapter. The integrated scheme with the use of the filtrate from the pretreatment of the CS and the growth conditions of Pleurotus cystidiosus is studied in the fourth chapter. The last chapter of this section provides the conditions of the key parameters in microfluidic systems (residence times, flow rates, concentrations) applied for a sequential process from liquid/liquid extraction of LVV-h7.
    Keywords: cellulose, lignin, biorefinery, thermodynamics, bioactive peptides, microfluidic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Do you want to know the details that should be taken into consideration in order to have accurate conventional and real-time PCR results? If so, this book is for you. Polymerase Chain Reaction for Biomedical Applications is a collection of chapters for both novice and experienced scientists and technologists aiming to address obtaining an optimized real-time PCR result, simultaneous processing of a large number of samples and assays, performing PCR and RT-PCR on cell lysate without extraction of DNA or RNA, detecting false-positive PCR results, detecting organisms in viral and microbial diseases and hospital environment, following safety assessments of food products, and using PCR for introduction of mutations. This is a must-have book for any PCR laboratory.
    Keywords: gene expression, pcr, microrna, food safety, microorganisms, dna ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book serves as a comprehensive survey of the impact of vitamin K2 on cellular functions and organ systems, indicating that vitamin K2 plays an important role in the differentiation/preservation of various cell phenotypes and as a stimulator and/or mediator of interorgan cross talk. Vitamin K2 binds to the transcription factor SXR/PXR, thus acting like a hormone (very much in the same manner as vitamin A and vitamin D). Therefore, vitamin K2 affects a multitude of organ systems, and it is reckoned to be one positive factor in bringing about "longevity" to the human body, e.g., supporting the functions/health of different organ systems, as well as correcting the functioning or even "curing" ailments striking several organs in our body. Vitamin K2 - Vital for Health and Wellbeing has been produced and distributed through the support from Kappa Bioscience, Norway.
    Keywords: nf-κb, drug delivery, bacteria, hepatocellular carcinoma, cardiovascular, osteoporosis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Protein phosphorylation reactions are carried out in a cell by protein kinases, which predominantly use ATP as a phosphate donor that is transferred and covalently bound to an amino acid on a substrate protein. Protein phosphorylation was discovered in 1954 by Edmond Fischer who shared the Nobel Prize in Medicine or Physiology in 1992 with Edwin Krebs. There are so many kinases that one was called "Just Another Kinase" for JAK kinase. Their counterpart is protein phosphatases that remove phosphates from phosphorylated proteins. Kinases and phosphatases act as switches in the cell that activates or inactivates protein functions. These reactions are reversible; the cell can quickly react to a situation but can then go back to its initial state.
    Keywords: cancer, biomarker, biosensor, aggregation, spinal cord injury, neurotoxicity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.
    Keywords: flavonoids, cancer, oxidative stress, medicinal plants, bioactive compounds, essential oils ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Most will agree that one major achievement in the bio-separation techniques is affinity chromatography. This coined terminology covers a myriad of separation approaches that relies mainly on reversible adsorption of biomolecules through biospecific interactions on the ligand. Within this book, the authors tried to deliver for you simplified fundamentals of affinity chromatography together with exemplarily applications of this versatile technique. We have always been endeavor to keep the contents of the book crisp and easily comprehensive, hoping that this book will receive an overwhelming interest, deliver benefits and valuable information to the readers.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Sugars, with a scientific term as saccharides, are involved in various aspects in the lives of human beings, including the sense of taste, energy for daily life, etc. Recent development in polysaccharides, as well as the background knowledge in this field, further deepens insight into their roles as healthy supplements. In this book, the principles on polysaccharides' solubility and structure, methodologies and application of polysaccharides have been reviewed. The chapters in this book include the relationship between structure and solubility of polysaccharide, the experimental and computational researches on polysaccharide solubility and the common polysaccharide, which may further aid scholars and researchers in regard to solubility of polysaccharides, methodologies and modification.
    Keywords: chitosan, antioxidant activity, chitin, rheology, hydrolysis, osmotic pressure ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 25
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Phenolic compounds are considered secondary metabolites within the physiology of a plant. They have different functions, such as pollination systems, sun protection, protection against pathogens and diseases, etc.Research on these compounds has increased due to the number of molecules they can include and the different biological activities they demonstrate. It is important to know the methods of extracting molecules, the biosynthesis routes, and their relationship with activities that can benefit from their consumption. Therefore, the book includes chapters that provide information on extraction and optimization techniques, biosynthetic pathways, and the identification and characterization of miRNAs involved in the regulation of their biosynthesis.
    Keywords: polyphenols, oxidative stress, antioxidant, nutrition, bioactive compounds, metabolism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The purpose of this book is to concentrate on recent developments on fatty acids. The articles collected in this book are contributions by invited researchers with a long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with general background in many different biological sciences. This volume offers you up-to-date, expert reviews of the fast-moving field of fatty acids. The book is divided into four major sections: (1) Fatty Acids in Physiopathology, (2) Fatty Acids and Cancer, (3) Fatty Acids in Aquatic Organisms, and (4) Fatty Acids in Veterinary and Dairy Products.
    Keywords: cancer, microalgae, inflammation, pregnancy, nutrition, cardiovascular disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Climate resilience and growing population are the two main global challenges that encourage the development of an affordable and sustainable source of vegetable protein to ensure future food security. Advanced scientific programs and agro-food developments should be proprietarily on-demand to face different stresses in order to maintain yield and quality of seed production. In this regard, legume crops are key sustainable alternatives for healthier diets while contributing to appropriate natural resource management. Taken together, the 11 chapters in this book represent a generous addition to the progress in our understanding of climate-resilient legumes, hoping to contribute to the improvement of global food security in the future.
    Keywords: nutraceuticals, functional properties, bioactive peptides, essential amino acids, cancer, diabetes mellitus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book covers new systems in technology that have developed our knowledge of ion exchange. This book discusses ion exchange resins to enhance cell growth; anion exchange membrane; nanosystems in ion exchange and ion exchange in environmental applications. The ion exchange system is used in bionanotechnology, cosmetic industry and water treatment.
    Keywords: chitosan, drug delivery, biomarker, water, nanotechnology, polymer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 29
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The peripheral membrane proteins transduce the extracellular signaling into the cells. The peripheral membrane proteins include the G protein-coupled receptors, receptor tyrosine kinases, channels and transporters. The signals, which are transduced via the peripheral membrane proteins, activate several pathways including G protein signaling, MAPK signaling, TNF signaling, TGF? signaling, Wnt signaling and Hedgehog signaling. The peripheral membrane proteins transduce the signaling from the extracellular ligands into the cells. This book intends to provide a comprehensive overview of the features and signaling of peripheral membrane proteins, which includes the molecular structure and interaction. The insights into membrane proteins associated with diseases and therapeutics and the effects of drugs and chemicals are also discussed in this book.
    Keywords: innate immunity, prostate cancer, yeast, signal transduction, crystallization, morphogenesis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Some New Aspects of Colloidal Systems in Foods is a new book on food emulsions, which provides in-depth coverage of some new aspects of food colloids. The coverage includes confident overviews of theoretical issues as well as descriptions of new techniques and recent colloid research findings. Specific topics include the role of electrostatic and steric forces in the stabilization of food colloids, antioxidants in food emulsions, nanoemulsions, and nanostructured colloids in food science. This book can be used as a specialized text for graduate students and researchers in food science and technology. In addition, it will serve as a reference text for advanced students in chemistry, engineers, biochemists, nutritionists, and analytical chemists in the food industry and research.
    Keywords: oxidative stress, antioxidants, safety, food industry, nanoemulsions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: The book "Progress in Carotenoid Research" presents an authoritative and comprehensive overview of the biology, biochemistry, and chemistry of carotenoids. Divided into 14 discrete parts, this book covers topics on basic science and applied technology of carotenoid molecules. This book provides an insight into future developments in each field and has an extensive bibliography. It will be an essential resource for researchers and academic and industry professionals in the natural pigment field.
    Keywords: carotenoids, astaxanthin, lycopene, remote sensing, mass spectrometry, fermentation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book provides an overview of secondary metabolites in three sections: “Introduction”, “Secondary Metabolites: General Reviews and Biotechnological Interventions” and “Plant Secondary Metabolites.” It discusses the antimicrobial, anticancer, and antioxidant activities of secondary metabolites, biotechnological interventions in the production and research of secondary metabolites, and the secondary metabolites of plants.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 33
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    Publication Date: 2024-04-05
    Description: The presence of flavonoids such as chalcones, flavones, flavonols, anthocyanins, and proanthocyanidins is ubiquitous throughout the plant kingdom. It was previously believed that the oldest plants that produced flavonoids were liverworts and mosses. However, recent discoveries have found genes encoding enzymes in the shikimate pathway responsible for flavonoid biosynthesis in a variety of plants including algae, liverworts, mosses, lycophytes, ferns and horsetails, gymnosperms, and angiosperms. These genes include the first two enzymes for flavonoid biosynthesis, chalcone synthase and chalcone isomerase. Furthermore, recent research has found flavones, isoflavones, and flavonols in microalgae from five distinct evolutionary lineages(Cyanobacteria, Rhodophyta, Chlorophyta, Haptophyta, and Ochrophyta) using ultra-high performance liquid chromatography with tandem mass spectrometry. This implies that plants may have developed the capacity to make flavonoids earlier than previously believed. Flavonoids in the earliest plants that produced them were believed to have acted as protection against UV radiation and control of plant hormone activity. As plants evolved, these roles diversified, and the study of flavonoids has revealed how plants developed the capacity to produce a wide array of specialized metabolites and then evolved the metabolic pathways required to manufacture them. This book delves into the structural diversity of flavonoids found throughout the plant kingdom, the evolution of flavonoid biosynthesis genes in plants, and the molecular interaction of flavonoids with growth hormones. The metabolic routes of flavonoids are thoroughly investigated using both biochemical and molecular biology methods, and the book elucidates the links between genes/proteins and metabolites, as well as between metabolites. The book also explores the interplay between flavonoid metabolism and external environmental factors that are subject to continuous change.
    Keywords: flavonoids ; biosynthesis ; agriculture ; bioactive compounds ; secondary metabolites ; genetic engineering ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways.
    Keywords: cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: B-group vitamins are involved in numerous metabolic reactions and their widespread deficiency can cause a large series of health problems. The aim of this book is to provide an update on the current use and perspectives of B-group vitamins. Novel methods to detect folates in pregnant women, the use and role of folate dentistry, the use of genotype notification to modify food intake behavior, thiamin metabolism in Archaea and its role in plants and in crop improvement, the use of riboflavin in blood safety and niacin in metabolic stress and resistance in dairy cows are some of the subjects that are described in this multitopic book written by authors from seven different countries.
    Keywords: folate, oxidative stress, stress, insulin, dentistry, polymorphism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 37
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    Publication Date: 2024-04-05
    Description: Iron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: This book is an excellent compilation of trace elements and their positive and negative effects on human health and the environment. Over two sections, the book examines the adverse effects of trace elements in the human body and the atmosphere and how to overcome them.
    Keywords: oxidative stress, breast cancer, antioxidant, public health, genotoxicity, environmental hazards ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: Bisphenol A (BPA) is a synthetic compound for hardening and clearing polycarbonate plastics. BPA is mainly classified as an estrogen-like endocrine-disrupting chemical. In the last decade, attention has arisen in scientific communities that it is not safe to use this chemical in mainly polycarbonate plastics. Exposure to BPA starts in prenatal period, which is the critical period for its toxic effects on different organs. Throughout this book, the readers will obtain information on the effects of BPA on different systems. They will also get information on the prenatal and postnatal effects of BPA. We believe that readers will get qualified scientific knowledge and a general overview of the toxic effects of BPA exposure and its consequences from this book.
    Keywords: steroidogenesis, gene expression, chronic kidney disease, reproduction, ovarian cancer, hemodialysis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 40
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    Publication Date: 2024-04-05
    Description: This is an introductory book on the role of potassium in health, physiology of potassium homeostasis, diagnostic approach to potassium derangement, and clinical management of potassium disorders. It is a concise, easy-to-read reference for students in the health professions, mid-level providers, house staff trainees, and clinicians.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 41
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    Publication Date: 2024-04-05
    Description: An interdisciplinary bioinformatics science aims to develop methodology and analysis tools to explore large-volume of biological data using conventional and modern computer science, statistics, and mathematics, as well as pattern recognition, reconstruction, machine learning, simulation and iterative approaches, molecular modeling, folding, networking, and artificial intelligence. Written by international team of life scientists, this Bioinformatics book provides some updates on bioinformatics methods, resources, approaches, and genome analysis tools useful for molecular sciences, medicine and drug designs, as well as plant sciences and agriculture. I trust chapters of this book should provide advanced knowledge for university students, life science researchers, and interested readers on some latest developments in the bioinformatics field.
    Keywords: databases, cancer, inflammation, data mining, targeted therapy, microbiome ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 42
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    Publication Date: 2024-04-05
    Description: Finding new strategies for synthesizing benzimidazole derivatives and functionalizing the benzimidazole core has proved to be important due to the compound's various applications in medicine, chemistry, and other areas. The multitude of benzimidazole derivatives marketed as drugs has led to intensive research in the field for the discovery of new biologically active structures. The general applications of benzimidazole derivatives in materials chemistry, electronics, technology, dyes, pigments, and agriculture open up new research horizons. This book guides the rational design of benzimidazole derivatives synthesis with certain applications. Chapters cover such topics as therapeutic use of benzimidazole in conditions like diabetes, viruses, and parasitic diseases; X-ray crystal structure of selected benzimidazole derivatives; benzimidazole compounds for cancer therapy; and others.
    Keywords: fluorescence, catalysis, anticancer, fuel cells, toxicology, inhibitors ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: By typing into databases such as Medline or PubMed the word “lipoprotein” one gets more than 100.000 hits that highlight the common interest in this topic. It is actually impossible to cover all aspects of lipoprotein structure, function, metabolism and pathophysiology in one issue like the present volume, but attempts have been made to concentrate on topics that are in focus of current lipoprotein research. These topics have been divided into 10 sections. This volume will help new investigators in the field to get acquainted with the general topic of lipoprotein research and will guide scientists interested in this area to emerging new fields.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 44
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    Publication Date: 2024-04-05
    Description: Terpenes belong to the diverse class of chemical constituents isolated from materials found in nature (plants, fungi, insects, marine organisms, plant pathogens, animals and endophytes). These metabolites have simple to complex structures derived from Isopentyl diphosphate (IPP), dimethyl allyl diphosphate (DMAPP), mevalonate and deoxyxylulose biosynthetic pathways. Terpenes play a very important role in human health and have significant biological activities (anticancer, antimicrobial, anti-inflammatory, antioxidant, antiallergic, skin permeation enhancer, anti-diabetic, immunomodulatory, anti-insecticidal). This book gives an overview and highlights recent research in the phytochemical and biological understanding of terpenes and terpenoid and explains the most essential functions of these kinds of secondary metabolites isolated from natural sources.
    Keywords: biosynthesis, malaria, plasmodium falciparum, biological activities, mechanisms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 45
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    Publication Date: 2024-04-05
    Description: This book offers a broad understanding of bioethanol production from sugarcane, although a few other substrates, except corn, will also be mentioned. The 10 chapters are grouped in five sections. The Fuel Ethanol Production from Sugarcane in Brazil section consists of two chapters dealing with the first-generation ethanol Brazilian industrial process. The Strategies for Sugarcane Bagasse Pretreatment section deals with emerging physicochemical methods for biomass pretreatment, and the non-conventional biomass source for lignocellulosic ethanol production addresses the potential of weed biomass as alternative feedstock. In the Recent Approaches for Increasing Fermentation Efficiency of Lignocellulosic Ethanol section, potential and research progress using thermophile bacteria and yeasts is presented, taking advantage of microorganisms involved in consolidating or simultaneous hydrolysis and fermentation processes. Finally, the Recent Advances in Ethanol Fermentation section presents the use of cold plasma and hydrostatic pressure to increase ethanol production efficiency. Also in this section the use of metabolic-engineered autotrophic cyanobacteria to produce ethanol from carbon dioxide is mentioned.
    Keywords: fermentation, pretreatment, bioethanol, lignocellulosic biomass, saccharomyces cerevisiae, bacteria ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 46
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    Publication Date: 2024-04-05
    Description: Nitric Oxide Synthase - Simple Enzyme-Complex Roles provides information on nitric oxide synthase, a biomolecule of key importance for the different biological systems, including central and peripheral nervous, cardiovascular, and reproductive systems. With recent links to the role of nitric oxide in the reactions that can impact cell signaling, and discoveries surrounding the complex role of nitric oxide synthase that have increased research attention across the fields of cell and molecular biology, physiology, pharmacology, toxicology, neuroscience, cardiology, urology, and endocrinology, this book tries to provide a comprehensive overview of biology/pathobiology of nitric oxide synthases and a perspective from possible therapeutic indication of the enzyme inhibitors.
    Keywords: spermatozoa, oxidative stress, breast cancer, depression, toxicity, infection ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: This book examines the sometimes controversial role of vitamin D in various health problems. Divided into four sections, chapters cover such topics as vitamin D deficiency in women, newborns, and the elderly, as well as the role of vitamin D in COVID-19, autism spectrum disorder, diabetes, dental diseases, and central nervous system pathological processes.
    Keywords: alzheimer’s disease, pregnancy, aging, stroke, neurodegeneration, elderly ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: This book is the most up-to-date research on vitamin A. It is designed for scientists and researchers to deepen their knowledge in this critical knowledge field, and it is a solid resource that brings together multidisciplinary research, development and innovation for a varied analysis of vitamin A.
    Keywords: human health, ulcerative colitis, micronutrients, biofortification, myopia, stem cell niche ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: DNA damage response (DDR) and lesion repair are vital processes ensuring genome integrity through various pathways depending mainly on the nature of DNA injury and cell cycle stage. DDR is finely regulated at many levels in co-ordination with other ongoing processes as is genome replication and cell cycle progression. Posttranslational modifications (PTMs), affecting both protein-protein and protein-DNA interactions, play a crucial role in finely tuning all processes involved in the restoration of genome lesions. Regarding damaged chromatin, PTMs serve in many cases as recruitment platforms for DNA repair mechanisms by facilitating binding sites or regulating interactions between involved proteins. Ubiquitination, the addition of ubiquitin moieties on a target protein, apart from controlling protein availability through degradation, is also involved, together with partner small ubiquitin-like modifier (SUMO), in controlling many pathways involved in DDR by modifying the structure-function relationship and thus interacting with partner molecules. The aim of this book is to cover a broad spectrum of current topics in ubiquitination and to a lesser extent SUMOylation involvement in regulation of DDR and repair in health and disease. This book is intended for pre- and postgraduate students and young scientists in this field. Members of both academic and research institutions, actively involved in the field, have described their current understanding of major mechanisms involved, highlighted key events, described ongoing applications in both developmental diseases and cancer and provided hints for future potential applications.
    Keywords: ubiquitylation, autophagy, dna damage, multiple myeloma, brca1, target therapy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Proteomics was thought to be a natural extension after the field of genomics has deposited significant amount of data. However, simply taking a straight verbatim approach to catalog all proteins in all tissues of different organisms is not viable. Researchers may need to focus on the perspectives of proteomics that are essential to the functional outcome of the cells. In Integrative Proteomics, expert researchers contribute both historical perspectives, new developments in sample preparation, gel-based and non-gel-based protein separation and identification using mass spectrometry. Substantial chapters are describing studies of the sub-proteomes such as phosphoproteome or glycoproteomes which are directly related to functional outcomes of the cells. Structural proteomics related to pharmaceutics development is also a perspective of the essence. Bioinformatics tools that can mine proteomics data and lead to pathway analyses become an integral part of proteomics. Integrative proteomics covers both look-backs and look-outs of proteomics. It is an ideal reference for students, new researchers, and experienced scientists who want to get an overview or insights into new development of the proteomics field.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Although additives are regularly used in the food industry to improve the organoleptic properties or extend the shelf life of food products, some additives are known to be potentially hazardous if consumed in excess. Increasingly, consumers are avoiding these types of products, highlighting an overall trend toward developing a green and sustainable economy and the emergence of natural additives with equal or greater benefits than synthetic ones. This book is an introduction to the use of natural food additives. It includes eleven chapters that discuss emerging compounds used as food additives and active packaging, molecular gastronomy, enzyme production in the food industry, and much more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: This book highlights recent advances on vitamin C and related topics. The chapters of this book include basic information about vitamin C function, sources and analysis, and radioprotective and antioxidant effect of vitamin C. Also, the anticarcinogenic effect of vitamin C is introduced. Furthermore, we considered the encapsulation technique used in vitamin C preparation. Finally, recent advances in vitamin C transporter are illustrated.
    Keywords: oxidative stress, antioxidant, cancer, heavy metals, biomarker, sensors ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: Pectin is an industrial product of certain fruit peels that contain it, such as citrus fruits, apples, pears, grapes, plums, beets, sunflowers, and so on. It is the traditional gelling agent for jams and jellies, but its applications extend to fruit products for food, dairy, dessert, soft drink, pharmaceutical, and other industries. This book discusses pectin production, pectin biotechnology, and pectin applications. Chapters cover such topics as the production of pectin from citrus, fungal pectinases in food technology, pharmaceutical applications of pectin, and more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 54
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    Publication Date: 2024-04-05
    Description: It is my great honor and pleasure to introduce this comprehensive book to readers who are interested in carbohydrates. This book contains 23 excellent chapters written by experts from the fields of chemistry, glycobiology, microbiology, immunology, botany, zoology, as well as biotechnology. According to the topics, methods and targets, the 23 chapters are further divided into five independent sections. In addition to the basic research, this book also offers much in the way of experiences, tools, and technologies for readers who are interested in different fields of Glycobiology. I believe that readers can obtain more than anticipated from this meaningful and useful book.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Phytochemicals are biologically active compounds present in plants used for food and medicine. A great deal of interest has been generated recently in the isolation, characterization and biological activity of these phytochemicals. This book is in response to the need for more current and global scope of phytochemicals. It contains chapters written by internationally recognized authors. The topics covered in the book range from their occurrence, chemical and physical characteristics, analytical procedures, biological activity, safety and industrial applications. The book has been planned to meet the needs of the researchers, health professionals, government regulatory agencies and industries. This book will serve as a standard reference book in this important and fast growing area of phytochemicals, human nutrition and health.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Lipoproteins have key roles in human growth and development, along with promoting, preventing, and/or participating in the pathogenesis or in the treatment of various diseases. This book presents a systematic and comprehensive review about the structure and metabolism of lipoproteins, particularly highlighting the crucial role of those molecules in the body and considering the interest of some lipids in healthy and diseased conditions. This book aims to provide integrative approach to understand the lipoprotein metabolism. Distinguished international experts contributed six chapters about the genetic variations, plasma lipoprotein components, and molecular relationship of lipoproteins with cognition and obesity.
    Keywords: inflammation, oxidative stress, infection, atherosclerosis, neurodegeneration, colorectal cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: This book provides insights into a wide range of topics related to milk protein. The chapters of this book will be of significant value to those interested in dairy foods, milk chemistry, cheese production, human health, neonatal development, lactation and mammary gland biology, and milk protein production. These chapters explore a range of topics related to milk protein, including: bioactivities of milk proteins and the peptides generated from those proteins; novel functions ascribed for some milk proteins; how processing of milk can impact milk proteins; allergies associated with consumption of milk; genetic variation of milk proteins; application of genomic technologies to explore expression of proteins during milk synthesis; and production of milk and milk protein as affected by environmental factors.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: Vitamin D is a unique bioregulatory molecule that can be synthesized in the skin as well as obtained via dietary sources. Vitamin D and its specific role in numerous diseases is a hot topic of scientific research. This book presents new insights into the specific role of vitamin D deficiency in the pathophysiological and biochemical mechanisms of many diseases. It is organized into four sections that present the latest data from clinical and preclinical investigations of the consequences of vitamin D deficiency in children and in diseases such as COVID-19 as well as cardiovascular, metabolic, endocrine, and renal disorders.
    Keywords: covid-19 ; schizophrenia ; obesity ; diabetes mellitus ; pandemic ; adolescents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: Essential oils have recently received much attention globally due to the increased use of essential oils as well as the positive impacts from economic backgrounds. New compounds of essential oils have been discovered from medicinal plants and used in anti-disease treatment as well as in most houses as a source of natural flavor. This book covers some interesting research topics for essential oils, including identification of active ingredients from wild and medicinal plants. This book will add significant value for researchers, academics, and students in the field of medicine.
    Keywords: cardiovascular disease, hypertension, biotechnology, natural products, antibacterial, endothelial dysfunction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Genotyping, a methodological process of detecting the allelic content of loci in a given genome, helps to reveal differences between and among individuals of comparisons. It helps in diagnostics and treatment of diseases, molecular breeding of agricultural crops, barcoding of unique biological materials, solving forensics issues, and/or controlling the spread of pathogens by tracing the origin of outbreaks. This Genotyping book aims to provide readers with an overview of the basics of genotyping process, available approaches and protocols, as well as novel, low-cost, high-throughput whole-genome genotyping tools and genotype data handling with the examples of genotyping applications in some organisms.
    Keywords: evolution, drug resistance, pathogens, staphylococcus aureus, hepatitis c virus, next-generation sequencing ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Antioxidants are one of the most sought-after biological compounds of interest to both scientific and nonscientific communities. The term gained popularity with the advent of identifying these compounds as having the ability to maintain health and wellness by combating against pathways leading to non-communicable diseases. This book covers several aspects of antioxidants—mechanisms of action, assays of measuring potency, sources, and even methods of isolation and identification. While it may seem these aspects have been covered in depth in several publications before this, this book intends to be positioned as an update, especially since the area of antioxidant research is as dynamic as ever. There are several chapters that might be of interest to health buffs, specifically those who are quite keen on maintaining health and wellness.
    Keywords: oxidative stress, diabetes, phytochemicals, reactive oxygen species, carotenoids, free radicals ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Fatty acids are considered as a very important category of chemical compounds to human health as well as from an industrial perspective. This book intends to provide an update on fatty acid research, their methods of detection, quantification, and related diseases such as cardiovascular disease and diabetes. Cyclic fatty acids are also covered, along with short chain fatty acids, which are important to the human gut microbiota. Fatty acids are important in the chemical structure of the cell membrane and its pivotal role in this aspect is reviewed herein. The book also contains a chapter that deals with some unpublished molecular aspects concerning the roles of fatty acids in depression and bipolar disorder. All in all, the book provides a brief overview of both highly explored as well as overlooked perspectives of fatty acids, while highlighting its significance as a biochemical molecule, which is imperative to the livelihood of unicellular and multi-cellular organisms alike.
    Keywords: obesity, metabolism, gut microbiota, cardiovascular diseases, lipids, nutraceuticals ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The global food industry has the largest number of demanding and knowledgeable consumers: the world population of seven billion inhabitants, since every person eats! This population requires food products that fulfill the high quality standards established by the food industry organizations. Food shortages threaten human health and are aggravated by the disastrous, extreme climatic events such as floods, droughts, fires, storms connected to climate change, global warming and greenhouse gas emissions that modify the environment and, consequently, the production of foods in the agriculture and husbandry sectors. This collection of articles is a timely contribution to issues relating to the food industry. They were selected for use as a primer, an investigation guide and documentation based on modern, scientific and technical references. This volume is therefore appropriate for use by university researchers and practicing food developers and producers. The control of food processing and production is not only discussed in scientific terms; engineering, economic and financial aspects are also considered for the advantage of food industry managers.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Marine organisms have been under research for the last decades as a source for different active compounds with various biological activities and application in agriculture, pharmacy, medicine, environment, and industries. Marine polysaccharides from these active compounds are used as antibacterial, antiviral, antioxidant, anti-inflammation, bioremediations, etc. During the last three decades, several important factors that control the production of phytoplankton polysaccharides have been identified such as chemical concentrations, temperature, light, etc. The current book includes 14 chapters contributed by experts around the world; the chapters are categorized into three sections: Marine Polysaccharides and Agriculture, Marine Polysaccharides and Biological Activities, and Marine Polysaccharides and Industries.
    Keywords: drug delivery, chitosan, chitin, alginate, nanoparticles, aquaculture ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The chapters in this book are written by a team of well-reputed international researchers. The objective is to provide advanced and updated information related to protein-protein interactions. I hope the methods, resources and approaches described here will enhance the available knowledge of the reader significantly.
    Keywords: nanoparticles, proteomics, confocal microscopy, immunochromatography, fret ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Pectin is mostly obtained from apple pomace and citrus peels and is used to influence the textural attributes of cooked gari and fufu dough. There are a number of other underutilized sources of pectin; it can be extracted and processed from a variety of agro-industrial byproducts, including pulps, husks, hulls, peels, cactaceae, and vegetables. Pectinase enzymes are found in a wide range of organisms. This book represents and discusses the various extraction methods used to extract pectin from different sources, including such as microwave heating processes and ultrasonic treatment. The information in this book will be useful in the food and pharmaceutical industries as well as to readers seeking to learn about sources, extraction, and applications of pectin.
    Keywords: secondary metabolites ; functional properties ; isolation ; agricultural waste ; industrial applications ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of flavonoids and on their roles in mammal metabolism. This book reviews most of the well-established activities of flavonoids, and we also present more recent research studies on the area of flavonoids, including the chemical aspects of structure characterization of flavonoids, the biosynthesis of flavonoids in model plants as well as their role in abiotic stress situations and in agriculture, the role of flavonoids in metabolism and health and their importance in foods, from consumption to their use as bioactive components.
    Keywords: natural products, anthocyanins, isolation, cancer, antioxidants, agriculture ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The purpose of this book is to concentrate on recent developments on lipid peroxidation. The articles collected in this book are contributions by invited researchers with a long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with general background in many different biological sciences. This volume offers you up-to-date, expert reviews of the fast-moving field of Lipid Peroxidation. The book is divided in four mayor sections: 1-Lipid peroxidation: chemical mechanisms, antioxidants, biological implications; 2-Evaluation of lipid peroxidation processes; 3-Lipid peroxidation in vegetables, oils, plants and meats and 4-Lipid peroxidation in health and disease.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Carbohydrates are the most abound macromolecules on earth, and they serve different functions within the cell. The purpose of the book is to provide a glimpse into various aspects of carbohydrates by presenting the research of some of the scientists who are engaged in the development of new tools and ideas used to reveal carbohydrate metabolism in health and diseases and as material to mimic the carbohydrate surfaces that take part in molecular recognition, often from very different perspectives. This book covers broad topics in carbohydrate including quality carbohydrates on the prevention and therapy of noncommunicable diseases, lactate, and glycolysis, as biomass in biofuel production, targets for cancer treatment and as biomaterial.
    Keywords: cancer, biomass, obesity, ionic liquids, melatonin, metabolic syndrome ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: In this book, Vitamin E in Health and Disease, the chapter by Dr Lisa Schmölz et al., The Hepatic Fate of Vitamin E, includes the hepatic metabolism of vitamin E, its storage, release, distribution, and its effects on the metabolism in great detail, as well as its effect on the prevention of diseases, in addition to its role in anti-aging. The chapter by Dr Rusu Anca Elena reports on the effect of vitamin E in patients with hemodialysis. In a similar manner, the chapter of Drs Rayan Ahmed and Paul W. Sylvester describe g-Tocotrienol, a natural isoform within the vitamin E family of compounds, which displays potent antiproliferative, apoptotic and reversal of epithelial-to-mesenchymal-transition activity against breast cancer, employing treatment doses that have little or no effect on normal cell viability. The chapter by Milka Mileva and Angel S. Galabov describes how vitamin E could be recommended as a reliable agent, indeed as a component in multiorgan flu therapy. Last, Dr Juan José Godina-Nava et al. describe the cytoprotector effect of the 120-Hz electromagnetic fields in early hepatocarcinogenesis.
    Keywords: oxidative stress, breast cancer, cardiovascular diseases, anemia, hemodialysis, cytochrome p450 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Aflatoxins - Biochemistry and Molecular Biology is a book that has been thought to present the most significant advances in these disciplines focused on the knowledge of such toxins. All authors, who supported the excellent work showed in every chapter of this book, are placed at the frontier of knowledge on this subject, thus, this book will be obligated reference to issue upon its publication. Finally, this book has been published in an attempt to present a written forum for researchers and teachers interested in the subject, having a current picture in this field of research about these interesting and intriguing toxins.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: This book gives a current review of the links between the structure and function of hydrolases and ligases, as well as ideas for better using these critical enzymes. The book is split into two sections: “Cleavage” and “Ligases.” These enzymes are the biggest and most varied family of enzymes, allowing researchers to investigate the structural variety that underpins their different biological roles. In light of recent scientific advances, there is a desire to examine and update our knowledge of these enzymes’ functional and structural changes.
    Keywords: Enzymology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The term “reactive oxygen species” (ROS) refers to a group of reactive molecules and free radicals produced by molecular oxygen. In recent decades, there has been great interest in the role of ROS in various diseases. From basic science research to clinical trials, biomedical scientists have made rapid progress toward a better understanding of ROS-metabolizing systems and their role in health and diseases. This book includes sixteen chapters that address topics such as the history of ROS, its role in autoimmunity, neurodegeneration, and aging, and recent advances in various antioxidants and their therapeutic potential.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The book explores distinct aspects of protein purification and characterization steps. It discusses solubility problems, resin selection tricks, and essential credentials in a purification process. In addition, the book examines aggregation and proteinopathy-related protein detection methods and reviews several essential protein detection and characterization methods in cancer for diagnosis, prognosis, and therapy, such as enzyme-linked immunosorbent assay (ELISA), immunohistochemistry, flow cytometry, western blot, mass spectrometry, and others.
    Keywords: Proteins ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: This book provides the most current information on the effects of vitamin B deficiency as well as the roles of niacin (vitamin B3), pyridoxine (vitamin B6), folate (vitamin B9), and vitamin B12 in numerous disorders. Chapters discuss novel applications of B-complex vitamins, such as thiamin in patients with critical conditions, dietary supplements in the prevention of renal stones, and treatment of COVID-19. Throughout, the authors discuss the effects of vitamin B deficiency from retrospective, perspective, and prospective points of view.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Vitamin K is a fat-soluble vitamin and a significant hydrophobic signaling molecule, like vitamins A and D. Besides its classical functions as a cofactor of γ-glutamyl carboxylase, which catalyzes the γ-carboxylation of vitamin K-dependent proteins, vitamin K has novel physiological and pharmacological activities that have been elucidated in the past two decades. The discovery of detailed action mechanisms of non-classical activities of vitamin K and the development of novel derivatives with unique structural and biological profiles would improve the understanding of vitamin K functions and clinical applications. This book discusses the biology and chemistry of vitamin K, which is helpful for fundamental and clinical investigations.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The diverse phenomenon of post-translational modifications of biological macromolecules (proteins, lipids, and nucleic acids) includes phosphorylation, glycosylation, ubiquitination, nitrosylation, methylation, acetylation, lipidation, and proteolysis. The mechanism of protein glycosylation has an important role in the regulation of human health. This book identifies the fundamentals of glycosylation that help in understanding the concepts of protein glycosylation and its significance.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Biophysical chemistry is one of the most interesting interdisciplinary research fields. Some of its different subjects have been intensively studied for decades. Now the field attracts not only scientists from chemistry, physics, and biology backgrounds but also those from medicine, pharmacy, and other sciences. We aimed to start this version of the book Biophysical Chemistry from advanced principles, as we include some of the most advanced subject matter, such as advanced topics in catalysis applications (first section) and therapeutic applications (second section). This led us to limit our selection to only chapters with high standards, therefore there are only six chapters, divided into two sections. We have assumed that the interested readers are familiar with the fundamentals of some advanced topics in mathematics such as integration, differentiation, and calculus and have some knowledge of organic and physical chemistry, biology, and pharmacy. We hope that the book will be valuable to graduate and postdoctoral students with the requisite background, and by some advanced researchers active in chemistry, biology, biochemistry, medicine, pharmacy, and other sciences.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of these cells, we need better knowledge of their biology, their interaction with other cells (especially supporting niche cells), growth, maturation and also immigration of stem cells through body in normal and abnormal conditions. Also for clinical application we need to understand better, their separation methods and safe manipulation. This book is written to clarify some aspects of stem cell biology, their characteristics, assessment of damage to cells during ex vivo manipulation and also their role in a model of cancers (chronic myeloid leukemia).
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Embryonic stem cells are one of the key building blocks of the emerging multidisciplinary field of regenerative medicine, and discoveries and new technology related to embryonic stem cells are being made at an ever increasing rate. This book provides a snapshot of some of the research occurring across a wide range of areas related to embryonic stem cells, including new methods, tools and technologies; new understandings about the molecular biology and pluripotency of these cells; as well as new uses for and sources of embryonic stem cells. The book will serve as a valuable resource for engineers, scientists, and clinicians as well as students in a wide range of disciplines.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development.
    Keywords: Enzymology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: This edited volume is a collection of reviewed and relevant research chapters concerning developments within the field of lipid metabolism. It includes scholarly contributions from experts in the field that cover such topics as roles of lipids in cancer, analytical tools for lipid assessment in biological assays, plant lipid metabolism, the effect of nanoparticles on lipid peroxidation in plants, and fatty acid compositions in fermented fish products. This book provides a thorough overview of the latest research efforts by international authors on lipid metabolism, and opens new possible research paths for further novel developments.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 88
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    Publication Date: 2024-04-05
    Description: Naturally present bioactive compounds in plants are referred to as "Phytochemicals" and are being studied extensively for their role in human health. Studies have shown that they can have an important role to play in the prevention and management of several human diseases. Recognizing the increasing interest in this area, this book is being published in response to the need for more current information globally about phytochemicals and their role in human health. Chapters of the book are authored by internationally recognized authors who are experts in their respective field of expertise. The chapters represent both original research as well as up-to-date and comprehensive reviews. We are sure that the book will be an important reference source meeting the needs of a wide range of interest groups.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 89
    Publication Date: 2024-04-05
    Description: Pluripotent stem cells have the potential to revolutionise medicine, providing treatment options for a wide range of diseases and conditions that currently lack therapies or cures. This book describes methodological advances in the culture and manipulation of embryonic stem cells that will serve to bring this promise to practice.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: All living things are comprised of cells. A cell is the building block of complex organisms. All cells contain genetic material. Some cells contain subunits known as organelles that perform specific functions. Protein processing, energy generation, and macromolecular biosynthesis are some of the functions of organelles. Recently, advances in cell biology have elucidated new insights in cellular development and the unique functions of different types of cells. The era of biotechnology is rooted in biologics, and cell biology has delivered novel therapeutic candidates. Personalized medicine has its underpinnings in cell biology. Innovations in Cell Research and Therapy focuses on recent key advances that are transforming health and medical sciences. Understanding fundamental cellular processes, including cellular differentiation, the many applications of stem cells, natural and synthetic approaches for inducing apoptosis, and new insights into organelle biology and macromolecular processing are representative examples of the topics that are addressed in the chapters found in this book.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Soybean is an agricultural crop of tremendous economic importance. Soybean and food items derived from it form dietary components of numerous people, especially those living in the Orient. The health benefits of soybean have attracted the attention of nutritionists as well as common people.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Protein interactions, which include interactions between proteins and other biomolecules, are essential to all aspects of biological processes, such as cell growth, differentiation, and apoptosis. Therefore, investigation and modulation of protein interactions are of significance as it not only reveals the mechanism governing cellular activity, but also leads to potential agents for the treatment of various diseases. The objective of this book is to highlight some of the latest approaches in the study of protein interactions, including modulation of protein interactions, development of analytical techniques, etc. Collectively they demonstrate the importance and the possibility for the further investigation and modulation of protein interactions as technology is evolving.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 95
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Over the recent years, biochemistry has become responsible for explaining living processes such that many scientists in the life sciences from agronomy to medicine are engaged in biochemical research. This book contains an overview focusing on the research area of proteins, enzymes, cellular mechanisms and chemical compounds used in relevant approaches. The book deals with basic issues and some of the recent developments in biochemistry. Particular emphasis is devoted to both theoretical and experimental aspect of modern biochemistry. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in biochemistry, molecular biology and associated areas. The book is written by international scientists with expertise in protein biochemistry, enzymology, molecular biology and genetics many of which are active in biochemical and biomedical research. We hope that the book will enhance the knowledge of scientists in the complexities of some biochemical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of biochemistry.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 96
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book is intended to present current concepts in molecular biology with the emphasis on the application to animal, plant and human pathology, in various aspects such as etiology, diagnosis, prognosis, treatment and prevention of diseases as well as the use of these methodologies in understanding the pathophysiology of various diseases that affect living beings.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 97
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.
    Keywords: Proteins ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 98
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book on cell growth is the ideal resource for a scientist who wishes to learn more about cell growth topics. It provides information on plant growth hormones, kinetic studies on cell growth, growth of fungal cells and production, cell growth measurement, ion homeostasis response to nutrient deficiency stress in plants, intracellular lipid homeostasis in eukaryotes, and cell-based assays in cancer research. Each topic begins with a summary of the essential facts. Chapters were carefully edited to maintain consistent use of terminology and approach of covering topics in a uniform, systematic format.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 99
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: In mammalian blood plasma there exist some 6 major lipoprotein classes. Under physiological conditions lipoproteins are certainly beneficial as they transport nutrients and steroids to numerous organs for further metabolism. On the other hand, under pathophysiological conditions most lipoprotein classes promote atherogenesis except of HDL that are considered to be anti-atherogenic. Lipoprotein research is a wide field comprising basic science, analytical methods and clinical investigations. Thus this issue does not raise the claim to give a comprehensive picture of the current knowledge, but rather focuses on specific questions related to animal models in lipoprotein research as well as features of the most atherogenic lipoprotein, Lp(a).
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 100
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Vitamin C, or ascorbic acid, is mainly present in fruits and vegetables. The consumption of such foods is important since the human body does not have the ability to produce this essential micronutrient. Because it is water soluble, it can also easily be lost in cooking and long-term storage. Even though the role of vitamin C has been known since the early 1930s, only recently have researchers been actively studying and demonstrating its role and function in the treatment and prevention of many diseases. These studies will be the key to providing the scientific basis that explains why this simple but important vitamin possesses such a wide range of positive biological activities.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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