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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Global warming is imposing tremendous challenges upon human and otherwise biotic life on Earth. A warmer atmosphere holds more moisture. The consensus is that the moisture transport by the atmospheric circulation strengthens and makes already wet areas of moisture convergence wetter and already dry areas of moisture divergence drier. Therefore, the tropics and mid-to-high latitudes will get wetter and the subtropics will get drier. Without any change in the interannual variability of hydroclimate, the change in the mean hydroclimate would equally increase drought risk in some places and flood risk in others. Moreover, global warming will cause the interannual variability of the hydroclimate to intensify, which will induce more droughts and floods. Furthermore, the changing atmospheric circulation interaction with the land surface may cause storm track alterations and may play an important role in shaping moisture redistribution. The author's contributions have documented the precipitation trends in southeast of the US, the Nile River Basin Ethiopia, Iraq, the Huai River Basin of northern China, and the Qilian Mountains of western China. The precipitation predictability on both global and regional scales are also studied. The interaction among climate systems in southeast Asia is also explicitly documented.
    Keywords: El Niño ; winter weather types ; precipitable water ; surface water vapor pressure ; consistency ; interannual and long-term trend ; precipitation ; trend analysis ; Iraq ; climate projection ; CMIP5 ; groundwater levels ; rainfall ; temperature ; Mann–Kendall test ; Bayesian Ensemble Algorithm ; rainstorm process ; rainstorm intensity ; risk estimation and mapping ; CMIP6 ; risk prediction ; Southwest China ; rainstorm and flood ; spatial and temporal change ; atmospheric circulation ; rainfall change ; CHIRPS ; PERSIANN-CDR ; descriptive statistics ; non-parametric trends ; Google Earth Engine ; central Punjab ; climate change ; land cover/land use ; vegetation ; NDVI ; Huai River Basin ; trends and variability ; flood magnitude ; Qilian Mountains ; cyclones power dissipation index (PDI) ; monsoon trough ; El Niño southern oscillation (ENSO) ; Indian Ocean dipole (IOD) ; Walker circulation ; predictability ; global ; seasonal precipitation ; ENSO ; MJO ; climate trend ; land use land cover ; Nile River Basin ; water resources ; raindrop spectrum ; radar ; dynamic Z-I ; LSTM neural network ; precipitation estimation ; Loess Plateau ; spring maize ; relative soil moisture ; drought index ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
    Language: English
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint concerns topics on chemical, functional, and technological features of wheats to obtain wheat-based foods improved in phytochemicals. Genetic materials, from landraces to ancient and modern wheat varieties, characterized for their content of bioactive compounds, were exploited to produce superior staple foods. The study of other species allowed to identify functional ingredients, in wholemeals or in their by-products, useful in the enrichment of formulations for various cereal-based products. Further, in the optic of circular economy, it is of great interest the extraction of bioactive components from food processing waste belonging to the other crops to functionalize final products.
    Keywords: durum wheat ; diversity ; pigmented cereals ; phytochemicals ; anthocyanins ; antioxidant activity ; protein ; gluten ; wheat aleurone ; dietary fibre ; extraction process ; antioxidant ; bread ; arabinoxylans ; bakery ; biologically active substances ; DPPH assay ; nutritional value ; sensory properties ; pasta fortification ; hemp flour ; durum wheat cultivar ; amino acids ; fatty acids ; mineral fortification ; brewers’ spent grain ; bread-making ; circular economy ; common wheat ; emmer ; phenolics ; proteins ; sustainable food production ; bread wheat ; spelt ; fibre ; metabolites ; minerals ; fertilisation ; health benefits ; colour ; farinograph ; rheofermentograph ; viscoelastic behaviour ; bread shelf life ; crumb porosity ; cereals ; wholemeal ; biscuits ; phenolic acid compositions ; carotenoids ; consumer acceptance ; wheat quality ; genetic resources ; ancient wheat ; avocado wastes/by-products ; functional bread ; lactic acid bacteria ; sourdough ; peels ; pulp ; seeds ; polyphenols ; antioxidant properties ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Smart materials and structures are capable of active or passive changes in terms of shapes, properties, and mechanical or electromagnetic responses in reaction to an external stimulus, such as light, temperature, stress, moisture, pH, and electric or magnetic fields. They have attracted increasing interest for their enhanced performance and efficiency over a wide range of industrial applications, especially for aerospace. These require novel engineering approaches and design philosophies in order to integrate the actions of sensors, actuators, and control circuit elements into a single system that can respond adaptively to its surroundings. This reprint has collected cutting-edge research and recent advances in smart materials and structures, including seven original research papers and three review articles, co-authored by 65 scientists and engineers from 18 institutions and 3 industries. The research topics mainly cover advanced materials, applications of smart materials and structures, as well as recent development in sensing techniques. We hope this reprint will contribute to disseminating the latest progress in smart materials and structures, as well as stimulate the interest of its audience to work in this important and vibrant area to promote and benefit the multidisciplinary scientific communities.
    Keywords: textile-based mechanical sensors ; mechanism ; preparation ; advantages ; applications ; Artificial Neural Network (ANN) ; guided waves ; Structural Health Monitoring (SHM) ; Finite Element Analysis (FEA) ; damage detection ; metals ; composites ; aeroelastic stability ; bladed disk ; intentional mistuning ; piezoelectric material ; topological optimization ; microstructure ; high-entropy alloy ; mechanical property ; bipedal robot ; dynamics simulation ; MRE isolator ; vibration reduction control algorithms ; no-core fiber ; polyaniline ; polyacrylic acid ; pH sensor ; multimode interference ; gas foil bearing ; Inconel alloy ; sensing foil ; strain field ; temperature field ; thermomechanical coupling ; thermomechanical characterization ; rotor dynamics ; turbomachinery ; cholesteric liquid crystals ; electro-optic response ; polymer stabilization ; ion-trapping mechanism ; liquid metal ; stretchable conductor ; 3D printing ; high dynamic stability ; wearable devices ; biomimetic ; Venus flytrap ; smart ; composite ; mechanics ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, recent advancements in the field of pediatric tumors are discussed, and novel prognostic markers are critically appraised. Greater understanding of the heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with the potential to provide new prospects for precision medicine in pediatric oncology.
    Keywords: undernutrition ; obesity ; nutritional status ; childhood cancer ; overall survival ; event-free survival ; relapse ; treatment-related toxicity ; review ; sarcoma botryoides ; fertility-sparing surgery ; embryonal rhabdomyosarcoma ; genital tract ; prognosis ; treatment ; local debulking ; neoadjuvant chemotherapy ; radiation ; ovarian cancer ; adolescents ; diagnosis ; therapy ; guidelines ; children ; papillary thyroid cancer ; proto-oncogene B-raf gene (BRAF) ; craniopharyngioma ; recurrence ; risk factors ; youth ; acute lymphoblastic leukemia (ALL) ; child ; genetics ; CDKN2A/2B deletions ; fluorescent in situ hybridization (FISH) ; multiple-ligation probe amplification (MLPA) ; copy-number alterations (CNAs) ; risk stratification ; minimal residual disease (MRD) ; cardiotoxicity ; chemotherapeutics agents ; biomarkers ; omics technology ; medulloblastoma ; tumor ; histologic ; pediatrics ; micro-RNAs ; non-coding RNAs ; molecular subgroup ; stratification ; acute lymphoblastic leukemia ; proteomics ; oncology ; chemotherapy ; cardiac function tests ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Agricultural production management is facing a new era of intelligence and automation. With developments in sensor technologies, the temporal, spectral, and spatial resolution from ground/air/space platforms have been notably improved. Optical sensors play an essential role in agriculture production management. Specifically, monitoring plant health, growth conditions, and insect infestation has traditionally involved extensive fieldwork. We believe that sensors, artificial intelligence, and machine learning are not simply scientific experiments but opportunities to make our agricultural production management more efficient and cost-effective, further contributing to the healthy development of natural–human systems. This reprint compiles the latest research on optical sensors and machine learning in agricultural monitoring, including related topics: Machine learning approaches for crop health, growth, and yield monitoring; Combined multisource/multi-sensor data to improve the crop parameters mapping; Crop-related growth models, artificial intelligence models, algorithms, and precision management; Farmland environmental monitoring and management; Ground, air, and space platforms application in precision agriculture; Development and application of field robotics; High-throughput field information survey; Phenological monitoring.
    Keywords: soil moisture content ; spectral processing technology ; hyperspectral ; principal component analysis ; feature parameters extraction ; yield estimation ; rice ; unmanned aerial vehicle (UAV) ; tasseled cap transformation ; precision agriculture ; weed identification ; YOLOv4-Tiny ; attention mechanism ; multiscale detection ; angle normalization ; vegetation canopy reflectance ; geostationary satellite ; path length correction ; Minnaert model ; GOCI ; winter wheat ; LSTM ; LAI ; deep learning ; land use ; land cover ; classification ; random forest ; Sentinel data ; SRTM ; feature selection ; accuracy ; validation ; unmanned aerial vehicle ; soybean ; convolutional neural network ; multispectral imagery ; fusarium head blight ; texture indices ; machine learning ; cropland ; multi-seasonal ; fractal feature ; feature extraction ; accuracy evaluation ; black soil ; UAV ; chlorophyll ; fractional vegetation cover ; maturity monitoring ; anomaly detection ; smart agriculture ; detection of apple leaf diseases ; YOLOv5 ; transformer ; CBAM ; crop type classification ; multi-temporal ; remote sensing ; dairy cows ; body condition score ; 3D TOF sensor ; non-contact evaluation ; recognize area of interest ; sugarcane clones ; canopy cover ; light interception ; biomass ; cane yield ; peanut southern blight ; reflection spectrum ; spectral index ; continuous wavelet transform ; VGNet ; corn diseases ; leaf detection ; lightweight ; transfer learning ; agriculture ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Land degradation, exacerbated by climate change and rapid urbanization, poses significant threats to socio-economic development. There is an urgent need to explore land degradation and its associated ecosystem responses and the suitable pathways for sustainable development in urban and rural regions. This reprint comprises a collection of 16 articles, featuring 1 review article and 15 research articles. There are some key practical experiences and scientific findings to support the ecosystem change response to land degradation, through either theoretical works or empirical research, identifying the characteristics and solutions for sustainable development. Key scientific issues addressed include land use and land cover change, ecological impacts of urbanization, mechanisms of land degradation on ecosystems, and coordinated social, economic, and ecological development. This reprint encouraged scholars to share the latest advancements in the research framework, datasets, methods, and case studies for assessing land degradation and associated ecosystem responses. We expect this reprint will inspire broader reflection and discussion within academic community regarding the theories and practices concerning land degradation and associated ecosystem responses. It could be a valuable reference for exploring potential solutions towards achieving land degradation neutrality and promoting regional sustainable development.
    Keywords: ecological compensation ; ecosystem services ; opportunity cost ; ecological compensation priority ; land degradation ; dust emission ; wind erosion ; dust models ; dust cycle ; carbon cycle ; livestock carrying capacity risk ; planting and breeding balance ; northeast China ; farmland circulation ; differential circulation features ; driving mechanism ; plot level ; plains and mountainous areas ; Zhangye City ; ecological carrying capacity ; supply and demand ; priority areas ; agricultural ecological efficiency ; spatial-temporal evolution ; SBM model ; spatial Markov chain ; spatiotemporal changes ; driving factors ; agro-pastoral transitional zone ; management ; Bashang Plateau ; Populus simonii forest ; optimal plant cover ; leaf-area index ; Biome-BGC model ; urban resilience ; land use/cover change ; urbanization ; carbon neutrality ; Beijing-Tianjin-Hebei urban agglomeration ; surface thermal environment ; standard deviation ellipse ; Shijiazhuang ; wildfires ; natural protected areas ; decision support system ; scenario-based analysis ; soil salinity ; sodicity ; GIS ; RS ; leaching and gypsum requirement ; carbon and nitrogen pools ; soil quality ; carbon and nitrogen management index ; land use ; arid environment ; eco-compensation ; ecosystem service value ; PAHs pollution ; risk assessment ; industrial legacy sites ; vertical distribution ; land reuse ; drylands ; sediment connectivity ; degradation ; land use and land cover change (LULCC) ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: I am grateful to all the authors who contributed to this Special Issue and the referees for reviewing the manuscripts. Finally, I give my thanks to Ms. Alisa Si and all the editorial staff of Nanomaterials for their support during the publication of this Special Issue.
    Keywords: Si ; MnO2 ; rGO ; sea urchin-like structure ; lithium-ion battery ; high performance ; silica-based anode ; Ketjen Black ; electrochemical properties ; pseudocapacitor ; carbon nanotube ; polyaniline ; fractional-order circuit model ; memory effect ; fractional derivative ; zinc-ion batteries ; conducting polymers ; zinc-ion diffusion ; metal–organic framework ; supercapacitors ; energy density ; specific capacitance ; stability ; self-powered ; wearable flexible sensor ; energy harvesting ; human motion monitoring ; triboelectric nanogenerator ; NiMoO4@MnCo2O4 ; microstructure ; electrochemical performance ; cycling stability ; semiconductor superlattice ; dielectric capacity ; energy storage ; first-principles calculation ; supercapacitor ; organic crosslinked polymer ; porous carbon ; electrochemistry ; α-Fe2O3@MnO2 ; electrode materials ; flexibility ; hydrogen generation ; porous titanium oxide cage ; PtNi nanoparticles ; sodium borohydride hydrolysis ; NaBH4 ; graphene oxide ; catalytic activity ; hydrolysis ; aqueous zinc ion battery ; transition metal chalcogenides ; layered structure ; cathode ; energy storage mechanism ; g-C3N4 ; perovskite solar cells ; additive ; surface modifier layer ; Li-rich cathode material ; voltage and capacity fade ; testing mode ; cobalt-containing nanomaterials ; morphological design ; bio-derived hard carbon ; Coulomb efficiency ; Na-ion batteries ; storage mechanism ; fibrous phosphorus ; lithium-Ion battery ; anode ; CuMn2O4 ; nanosheet arrays ; hydrothermal ; battery-type ; CoO@rGO ; graphene ; MOF ; flexible electrodes ; hollow structure ; ultrafast integration ; lithium-ion batteries ; proton exchange membrane fuel cell ; mechanical vibration ; durability ; platinum migration ; accelerated stress test ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Land use is the projection of human activities in space, and it has become an important insight into the transformation and reconstruction of human society and economy. Rural land use in China is undergoing rapid transformation driven by the rapid development of science and technology. Effectively grasping the change and transformation process of rural land use and its internal mechanism provides an important reference for revealing the inherent laws of China's rural development. Rural land use is closely related to the rural vitalization strategy and urban–rural integration in the new era. An in-depth study of China's rural land use and policy reform provides the basis of knowledge for formulating and optimizing urban–rural relations. This Special Issue focuses on the changes, effects, and regulation of rural land use in China, focusing on its main contradictions and solutions, building a cooperative network and sharing platform for rural land use research from a multidisciplinary perspective, and further deepening the theoretical innovation and practical application of rural land use research. We invited scholars from various disciplines to contribute to the Special Issue, especially with papers on the subjects of theoretical innovation, technological innovation, and practical innovation in this field.
    Keywords: family farm ; efficiency ; DEA model ; Tobit model ; farm operation ; influencing factors ; soybean ; production pattern ; spatial agglomeration ; policy implications ; spatiotemporal changes ; crop planting structure ; black soil region ; Northeast China ; county-level ; geographic characteristics ; hollow village ; actor–network ; governance mode ; operation process ; appropriate tillage sand land ; land survey ; limiting factor ; land evaluation ; cultivated land protection ; Green Transition of Cultivated Land-use (GTCL) ; Water-Land-Food-Carbon (WLFC) ; coupling coordination ; land use change ; rural settlements ; spatial pattern evolution ; land policy ; China ; different modes ; land transfer ; livelihood capital ; difference-in-differences model ; Land Certificated Program (LCP) ; farmland “stickiness” ; land production function ; property rights ; agricultural policy ; cultivated land multifunctionality ; coupling coordination degree ; spatial-temporal pattern ; driving force ; major grain-producing areas ; northeast China ; comprehensive land consolidation ; pilot project ; decision-making evaluation ; farmers ; social investors ; non-agriculturalization rate ; ecological risk ; cultivated land change ; landform ; land management ; increasing versus decreasing balance (IVDB) ; balanced quota ; revenue ; inverted U-shaped curve ; Zhejiang province ; territorial space ; production–living–ecological space ; spatio-temporal variation ; eco-environment effect ; territorial spatial pattern ; eco-environmental quality ; soil contamination ; phytoremediation ; passivation ; farmer ; questionnaire survey ; paddy field ; dryland ; topographic gradient ; landscape characteristics ; land-use change ; rural settlement ; spatial distribution ; scale distribution ; morphological distribution ; the metropolitan fringe area ; Nanjing ; farmland transfer ; farmland function ; income structure ; rural household consumption ; consumption structure ; Yunnan Province ; farmers’ land transfer behavior ; herd effect ; geo-network ; the farmland right system reform ; creditor rights ; real rights ; agricultural modernization ; labor migration ; spatio-temporal evolution ; driving factor ; family structure ; heterogeneity ; area of land transfer ; rural–urban migration ; rural development ; land consolidation ; income distribution ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Recently, the trends of a circular economy and sustainability have driven nanotechnology towards the development of novel and innovative applications in the food packaging sector, which is rather recent compared with their use in biomedical and pharmaceutical applications. Bioactive films and coatings based on natural biopolymers such as chitosan, sodium alginate and gelatin and containing antioxidant and antimicrobial agents such as micro- and nanoemulsions of phytochemicals and nanostructured materials such as quantum dots, ZnO nanoparticles, nanoclays, silicas, zeolites and activated carbons, are finding application in various sectors of the food industry, especially in the development of novel edible, active packaging films and coatings. These bioactive films and coating materials enhance solubility, improve bioavailability, facilitate controlled release, and protect bioactive components during manufacture and storage. This Issue intends to provide an overview of bioactive gel films and coatings applied in active food packaging.
    Keywords: bioactive packaging ; xanthan ; propolis ; physicochemical properties ; microbiological analyses ; sensory evaluation ; biopolymers ; antimicrobial ; environment ; film ; coating ; active packaging ; soft cheese preservation ; sodium alginate ; thyme oil ; natural zeolite ; shelf-life extension ; anthocyanin ; fruit decay ; postharvest shelf life ; Aloe vera ; antioxidant ; fig ; purple-flesh sweet-potato ; chitosan ; gel coating ; preservation ; citrus ; cinnamon ; clove ; eucalyptus ; mint ; ginger ; chamomile ; halloysite ; polyvinyl alcohol ; gel ; active coatings ; nanostructures ; kiwi fruits ; green pea pods ; corn oil ; films ; hydrogel polymer ; acacia gum ; cinnamon essential oil ; edible hydrogel-based films ; food packaging ; edible films ; composite material ; essential oil ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The integration of information technologies with industry has marked the beginning of the fourth industrial revolution and promoted the development of industrial engineering. However, the depletion of resources and industrial waste caused by increasing amounts of industrial production pose a huge threat to nature. The application of sustainable supply chains in industrial engineering and management is one of the ways to balance the economy, society and environment. Therefore, it is a key concern for us to explore the construction of sustainable supply chains in industrial engineering and management. Moreover, to understand the impact of low-carbon, sustainable and recycled supply chains on industrial engineering, we need more in-depth investigations.This Special Issue aims to solicit original research and review articles discussing sustainable supply chain decision-making in industrial engineering and management to improve the sustainability of enterprise operations. Moreover, this Special Issue also shows mixed methods (e.g., modeling plus a case study) and rigorous quantitative/qualitative empirical studies of sustainable supply chains.
    Keywords: coordination degree model ; logistics industry ; digital economy ; industrial integration ; regional IEE system ; multimodel decision ; coupling coordination ; decision support methods ; online retailer ; consumer purchase behavior ; return strategy ; return insurance ; supply chain management ; real-time ; home delivery ; business modeling ; e-commerce ; time window ; lightweight ; carbon emissions ; low carbon benefits ; optimization design ; wheel hub ; subsidy policy ; remanufacturing industry ; donation strategy ; prisoner’s dilemma ; water-efficient products ; quality improvement ; DMAIC ; smart water closets ; carbon abatement ; cost sharing ; capital constraint ; environmental externality ; innovative products ; remanufacturing ; differential game ; bass model ; strategic emerging industries ; industrial structure ; employment effect ; artificial intelligence hardware ; data classification ; deep learning ; emission control ; industrial manufacturing ; bilateral matching decision making ; interval-valued hesitant fuzzy information ; bidirectional projection technology ; organizational quality-specific immunity ; automotive supply chain disruption ; supply chain resilience ; disruption risk ; bibliometric analysis ; co-citation analysis ; NGU ; self-attention ; CNN ; silver prediction ; data-driven ; composite systems ; synergy ; sustainability ; blockchain ; collection channel ; recycling strategies ; uncertain demand ; game theory ; federated learning ; intelligent manufacturing ; sustainable energy ; low-carbon strategy ; livestreaming marketing mode ; consumer low-carbon preference ; level of low-carbon promotion effort ; power structures ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on topics related to spintronic devices, such as spin-based magnetoresistive memories, multiferroic interconnects and sensors, microfluidic solenoid valves, and magnetoelectric antennas with broad practical applications.
    Keywords: optimization design ; magnetic isolation ring ; dynamic response characteristics ; simulation ; transition jitter ; heat-assisted magnetic recording ; magnetic footprints ; antenna miniaturization ; ME antenna ; mason equivalent circuit model ; finite element simulation ; high gain ; electrodeposition ; permalloy ; magnetoresistance ; MOKE ; AMR ; FMR ; planar hall effect ; gradiometer ; magnetic sensor ; synthetic multiferroic ; interconnects ; magnetic logic devices ; spintronics ; spin-transfer torque magnetic tunnel junctions (STT-MTJ) ; Ising annealing system ; combinatorial optimization problem ; magnetostriction ; magneto-deformation ; magnetoactive elastomer ; normal force ; hysteresis ; magnetorheological elastomer ; finite element method ; micromagnetics ; spin and charge drift-diffusion ; MRAM ; SOT-MRAM ; temperature scaling ; temperature effects ; incubation time ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHK Electricity, electromagnetism & magnetism
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Natura is a polysemic Latin word that has accompanied the historical development of the West for centuries, spreading around much of the globe with colonialism and imperialism. It has been adopted in numerous languages. Our relationship with nature has become a highly charged issue at least since the "ecological turn" around 1970. It is as much about the relationship of humans to the environment as it is about the relationship of humans to each other. In the course of these debates, research has intensified in various disciplines: history, anthropology, philosophy, literature, ecology, etc. The nine contributions gathered in this volume deal with the dimension of perception and its long-term development from the Middle Ages to the present time. They trace in detail how images of nature were adopted, modified, and transmitted for specific purposes in specific situations. The introduction to the volume provides an overview and brings the contributions together.
    Keywords: nature ; culture ; science ; religion ; European history ; scholasticism ; image of man ; Thomism ; medieval medicine ; anthropology ; Magnus Hundt ; human body ; Japan ; history of ideas ; environment ; pollution ; ecology ; physico-theology ; nature as a huge organism ; Alfred North Whitehead ; philosophy of nature ; philosophy of subjectivity ; metaphysics ; Donna J. Haraway ; anarchism ; naturalism ; Fin de Siècle ; pedagogy ; historical anthropology ; history of biology ; symmetrical history ; medieval breeding ; race ; ancestry ; Aristotelianism ; Albertus Magnus ; practical knowledge ; natural philosophy ; seventeenth century ; atomism ; corpuscles ; Humboldtian science ; barbarism ; savage ; civilization ; indigenous knowledge ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 13
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-09
    Description: This Special Issue reprint highlights seventy years since the discovery of carbon nanotubes (CNTs) in 1952 by Russian scientists LV Radushkevich and VM Lukyanovich in what was then the Union of Soviet Socialist Republics or the USSR. It also reflects the popularization by the well-known Japanese scientist S Iijima, since 1991, of carbon nanostructures, including CNTs, towards nanotechnology as a forever impactful and inspiring field. For researchers, academics, and teachers of all levels, from novice to expert to guru, the articles contained within this Special Issue are themed around sustainability from nanotechnology, pertaining to diameter measurement, rotor system molecular simulation, ultra-high tensile strength, energy, filtration via membrane distillation, environmental remediation using adsorption, ionic liquids as curing agents, biosensors and bioinspired sensors, and electrical/mechanical properties of polymer nanocomposites. The CNT is a legacy 1D nanomaterial, only after which was 2D graphene able to emerge. This is a global and mixed-country authorship Special Issue, with this reprint containing articles from Canada, Saudi Arabia, China, Russia, Spain, India, Japan, the United Arab Emirates (UAE), the USA, Germany, Turkiye, and Malaysia. The Guest Editor is from Singapore and began publishing critical work on the CNT-polymer interface towards the mechanical properties of the nanocomposite up to 20 years ago.
    Keywords: CNTs ; MWCNTs ; SWCNTs ; polymer composite ; mechanical performance ; flexible capacitive sensors ; bioinspired spinosum ; CNT/PDMS nanocomposite ; tires ; transmission system ; carbon nanotube (CNT) ; hydroxyl groups ; response speed ; energy dissipation ; carbon nanotubes ; carbon nanotube fibers ; tensile strength ; defect control ; controlled preparation ; dielectric polymer composites ; permittivity ; polymer nanocomposite ; electrical conductivity ; mixing ; polymer blends ; electromagnetic interference shielding ; carbon nanotube ; filler migration ; polyethylene ; lead ; arsenic ; adsorption ; poly(amidoamine) ; silver nanoparticles ; biosensor ; virus ; SARS-CoV-2 ; toxicity ; biocompatibility ; electrospinning ; electrospraying ; nanomaterials ; nanostructured membrane ; nanocomposites ; seawater desalination ; temperature polarization ; flux ; solar energy ; dye degradation ; surface plasmon resonance effect ; TiO2/rGO/Ag ; hybrid nanostructures ; phosphorus ; encapsulation ; lithium-ion batteries ; atomic force microscopy ; diameter ; nanometrology ; epoxy resin ; ionic liquid ; nanocomposite ; curing agent ; dispersing agent ; mechanical properties ; lap shear ; conductivity ; melt-mixing ; polymer composites ; SWCNT ; PMMA ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Implementing sustainable development is central to achieving global reductions in greenhouse gas emissions and mitigating anthropogenic environmental impacts. As defined by the UN 2030 Agenda and its associated Sustainable Development Goals (SDGs), sustainable development requires a holistic, interdisciplinary approach, which is not without its challenges. Indeed, studies tracking global progress toward meeting the 2030 SDG targets emphasize the importance of implementing sustainable solutions, with several SDG targets described as 'off track.' Therefore, there is an urgent need to address the challenges of an interdisciplinary, unified, and practical approach to sustainable implementation. In this context, this Reprint brings together 15 selected papers presented during the 2022 SDEWES Conference. These papers cover a broad range of topics, from circular governance models to education related to sustainable practices, as well as the impacts of current legislative frameworks targeting energy efficiency, built environment energy performance, bio-based industrial applications, transport and sustainable energy services, and production, supply, and infrastructure maintenance strategies. This Reprint provides an interdisciplinary and holistic perspective on sustainable development solutions, with several papers highlighting the interrelations between various fields and aspects of sustainability.
    Keywords: combined heat and power ; hospitality ; feasibility ; sensitivity analysis ; simple payback ; energy performance certificate ; CO2 ; multi-apartment buildings ; heating ; energy consumption ; cooling ; performance-based retrofit ; decision support ; building performance simulation ; parametric analysis ; multiple-criteria decision analysis ; residential buildings ; in-line inspection ; smart pig ; sensor ; oil ; natural gas ; pipeline ; environment ; biorefinery ; organosolv ; lignin ; pre-treatment ; higher education ; competencies development ; STEM education ; sustainability ; colloidal particles ; Pickering emulsion ; rheological behaviour ; ESCO business models ; aggregator business models ; energy services for buildings ; energy performance contract ; Pay-for-Performance contract ; energy efficiency in buildings ; demand response ; demand side flexibility ; residential sector ; governance ; circular economy ; circular territories ; index ; circularity ; thermal transmittance ; thermal resistance ; finite element method ; heat flux sensor ; in situ monitoring ; concrete masonry unit ; hydrogen ; water ; wastewater ; electrolysis ; water scarcity ; wastewater treatment plants ; desalination ; Jordan ; system dynamics ; thermal comfort ; Minha Casa Minha Vida ; natural ventilation ; bioclimatic architecture ; social housing ; energy poverty ; battery electric vehicles ; plug-in hybrid electric vehicles ; hybrid electric vehicles ; CO2 emissions ; Hofstede ; advertising ; sustainability integration ; Middle East ; supply chain management ; responsible logistics ; education for SDGs ; natural gas pipelines ; nondestructive testing (NDT) ; in-line inspection robot ; wireless communication ; antenna ; circular waveguide ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue is a collection of eleven articles (five reviews and six studies) that describe a wide range of approaches to modulating metalloproteinase activity in disease. The techniques described are in vitro, in vivo, and ex vivo.
    Keywords: carbohydrates ; glycoconjugates ; MMPs ; ADAMs ; iminosugars ; metzincin inhibitors ; matrix metalloproteinases (MMPs), protease ; tissue inhibitors of metalloproteinases (TIMPs), exosite ; small molecule inhibitors ; monoclonal antibodies ; proteomics ; N-terminomics ; terminal amine isotopic labeling of substrates (TAILS) ; MMP-2 ; MMP-9 ; Alzheimer’s disease ; AD ; neurodegeneration ; neuroinflammation ; natural compounds ; marine compounds ; terrestrial compounds ; nutraceuticals ; Matrix Metalloproteinase inhibitors ; bone targeting ; bisphosphonates ; antitumor agents ; skeletal malignancies ; osteoarthritis ; cartilage ; metalloproteinase ; targeting ; meprin α ; meprin β ; zinc metalloproteinase ; medicinal chemistry ; probe development ; uHTS ; dipeptidyl peptidase III ; coumarin derivatives ; inhibitor ; molecular modeling ; β-blockers ; carvedilol ; matrix metalloproteinase-2 ; ischemia-reperfusion injury ; isolated heart perfusion ; kidney ; obeticholic acid ; ischemia/reperfusion ; liver ; metalloproteinases ; MMP-2 inhibitor ; cardiac dysfunction ; ischemia ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression.
    Keywords: inflammatory bowel diseases ; cell autofluorescence ; immune cells ; NADH ; FAD ; flow cytometry ; multiphoton microscopy ; colitis ; colitis-associated cancer ; inflammatory bowel disease ; colorectal cancer ; colon adenocarcinoma ; ulcerative colitis ; Crohn’s disease ; cDNA microarray ; transciptomics analysis ; microarray ; inflammatory bowel diseases (IBDs) ; vasculature ; angiogenesis ; gut vascular barrier ; vessel permeability ; epithelial barrier ; homeostasis ; acetylcholine ; muscarinic receptor ; non-neuronal acetylcholine ; mucosal wound healing ; ferroptosis ; leaky gut ; inflammatory bowel disease (IBD) ; triple-culture ; Caco-2 ; HT29-MTX-E12 ; THP-1 ; monocyte-derived macrophage ; inflammation ; TEER ; FITC-dextran 4 kDa (FD4) ; pro-inflammatory cytokines ; HIF-1α ; PHD2 ; AKT ; intestinal epithelial cells ; probiotics ; LPS ; antigen-specific T-cells ; celiac disease ; gliadin ; IBD ; food antigens ; intestinal Behcet’s disease ; immune mechanism ; biological agents ; claudin ; tight junctions ; barrier function ; gut ; ZO-1 ; actin ; cell migration ; cell division ; colon cancer ; PMNs ; LDs ; FOXO3 ; n/a ; bic Book Industry Communication::M Medicine
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: To ensure global food and nutrition security, there is a need for a sustainable year-round supply of nutritious food systems such as fruits and vegetables. Over the years, there has been a surge in fruit and vegetable consumption due to their composition of health-promoting biomarkers such as vitamins, minerals, fiber, and bioactive polyphenols. However, producing fruits and vegetables with the valuable contents of these health-promoting biomarkers is dependent on various factors, such as growing degree days, genetic pool, and management practices. Thereby, the goal of this Special Issue (Fruits and Vegetables Production) of the MDPI journal Plants was to provide up-to-date knowledge on traditional and emerging novel technologies applicable in sustainable production of high-value fruits and vegetables at various stages of their field and greenhouse production chains. In summary, this reprint is produced from the Special Issue that reported 12 peer-reviewed manuscripts, with foci on: (1) crop response to different elicitors and (2) green non-destructive technologies for efficient profiling of biomarkers, quality parameters, and cultivar evaluation. Thus, this reprint bridges the gaps among stakeholders (i.e., researchers, policymakers, and industry) for efficient production of consumer-centric crops with high productivity, appreciable nutritional value, and post-harvest resilience.
    Keywords: antioxidant ; Brassica oleracea ; chlorophyll index ; membrane injury ; stomatal conductance ; water deficit ; water use efficiency ; rhizobacteria ; PGPR ; nutraceutical quality ; Solanum lycopersicum ; biostimulant ; pyroligneous acid ; vegetable production ; post-harvest ; Capsicum annuum L. ; maturation ; nutritional quality ; seed chemical composition ; β-carotene Cucumis melo ; flavonoids ; mineral element ; vitamin C ; fruit quality ; quality prediction ; plant phenotyping ; orchard management ; grape ; histamine ; putrescine ; agmatine ; dopamine ; spermine ; organic amendment ; plant metabolites ; soil health ; environmental health ; anthocyanin ; russeting ; silver patch ; Solanum tuberosum ; suberized cell layer ; surface cracking ; microgreens ; natural amendment ; phytochemicals ; healthy food ; common bean ; magnetic field ; photosynthesis ; physiological parameters ; seeds ; Carica papaya ; cultivation practice ; fruit development ; fruit tree ; greenhouse ; mineral distribution ; papaya fruit ; skin coloration ; nutrient ; ripening stages ; tropical ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Biomedical sensors stand at the forefront of modern medical technologies, serving as indispensable components in diverse instruments and equipment. These sensors unravel the intricacies of biological processes and medical interventions. The recent surge in high-density sensor systems, characterized by arrangements in matrix arrays and other configurations, has ushered in a new era of functional evaluation. This spans electrophysiological activity, the metabolic responses of organs and tissues, and motor control analysis, all enriched with crucial spatial information. Functional mapping, a burgeoning approach in various biomedical techniques such as EEG, EMG, ECG, NIRS, and MEG, is proving to be transformative. Its integration enhances our comprehension of complex biological behaviors, where the precise spatial localization of sensing methodologies becomes paramount. The applications of functional mapping using biomedical sensors extend across multiple fields, including neuroscience, neuromuscular physiology, rehabilitation, and cardiology. Its utility ranges from diagnostic purposes to assessing the effectiveness of therapeutic interventions. The primary objective of this reprint was to collect papers that delineate the forefront of techniques, methods, and applications in the realm of biomedical sensors. Additionally, the focus extends to specific algorithms for data processing, ensuring a robust understanding of functional information intricately associated with spatial localization.
    Keywords: EMG ; EEG ; rehabilitation ; neuromotor ; evaluation ; assessment ; review ; machine learning ; biofeedback ; transfer learning ; random forest classifier ; COVID-19 ; intubation ; tracheoesophageal fistula ; tracheal lesions ; acute respiratory distress syndrome ; modeling ; intensive care unit ; muscle synergies ; whole body FES ; neurological patients ; photodynamic therapy ; fluorescence ; laser ; fluorophores ; enamel ; effective connectivity ; kurtosis ; resting-state connectivity ; stationarity ; sleep monitoring ; pressure bed sensor (PBS) ; unobtrusive measure ; multi-scale analysis ; sleep apnea–hypopnea syndrome (SAHS) ; shift-working ; optically detected magnetic resonance ; quantum magnetometer ; magnetoencephalography ; time domain ; functional near infrared spectroscopy ; diffuse optics ; brain ; hemodynamics ; resting-state brain oscillation ; mental workload ; signal processing ; reliability ; cognitive performance ; Simon task ; emotion detection ; valence ; arousal ; wearable sensors ; regression ; classification ; technology acceptance model ; rehabilitation exoskeletons ; therapists ; neuro-rehabilitation ; multiple linear regression ; Pearson’s correlation ; integrated sensor systems ; hand function ; hand osteoarthritis ; electromyography ; diagnosis ; discriminant analysis ; photoplethysmogram ; microcirculation ; deep learning ; convolutional neural network ; modelling ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint describes the fate of pollutants transported to the sea from the mainland and how they accumulate in the marine environment and organisms. This will contribute to increasing the knowledge on the dangers of pollutants that reach the marine environment and their fate once they enter the marine food chain. We also hope to improve knowledge on the effects of the pollutant load on the sea during all the seasons, due to the contribution of rivers, rainfall, etc., and the relative influence on marine organisms.
    Keywords: Adriatic Sea ; Neretva Channel ; sediment dynamics ; age model ; metal concentrations ; toxic element ; Mediterranean Sea ; sponges ; biomonitoring ; northern Adriatic Sea ; anthropic signal ; trace metals concentration ; marine sediments ; zoobenthos ; sentinel species ; suspension feeders ; water pollutants ; bioaccumulation ; heavy metals ; trace metals ; beach sediments ; coastal processes ; lithology ; pollution indicators ; surficial sediments ; central western Adriatic Sea ; marine dumping area ; heavy metal ; dredged material ; benthic community ; Huangmao Island ; review ; DNA methylation ; genetic polymorphisms ; ecogenetics ; anthropology ; environmental pollutants ; methylmercury ; polycyclic aromatic hydrocarbons ; seafood ; PAH ; PCB ; neritic environment ; seawater ; sediment ; biota ; partition ; contamination ; Ionian Sea ; Tyrrhenian Sea ; database ; meta-analysis ; contaminants ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics ; bic Book Industry Communication::T Technology, engineering, agriculture::TQ Environmental science, engineering & technology::TQK Pollution control
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Numerous scientific research projects are concerned with improving and protecting the environment. The first steps towards solving the problem of environmental pollution include researching and monitoring the presence and concentration of pollutants, especially heavy metals. It is known from previous studies that fungi bioaccumulate high concentrations of heavy metals, the concentration of which depends, to a greater or lesser extent, on factors such as the species, sampling area, and anatomical parts of the fungus, but also the substrate on which they grow. As the concentration of heavy metals in fungi increases, the importance of fungi as bioindicators of environmental pollution also increases. However, extremely high concentrations of toxic heavy metals in fungi can have negative effects on human health. Constantly monitoring and controlling the levels of metals and metalloids in the human diet is necessary, both in foods of plant and animal origin and in food supplements, or in this case edible mushrooms, whose availability on the market and general popularity are constantly increasing. Therefore, this reprint provides good insights into the development of science and technology in relation to heavy metal concentrations in mushrooms.
    Keywords: bioaccumulation ; mushroom cultivation ; prediction models ; regression analysis ; waste management ; cluster analysis ; health risk ; potentially toxic elements ; mushroom ; spatial analysis ; principal component ; wild edible mushrooms ; metallic elements ; metalloids ; risk assessment ; human health ; organic food ; Boletus griseus ; Hypomyces chrysospermus ; cadmium ; symbiotic association ; health risk assessment ; heavy metals ; health hazard ; mushrooms ; Tricholoma spp. ; copper ; wood ; detoxification ; ligninolytic fungi ; oxalate ; biosorption ; accumulation ; basidiomycete ; bioremediation ; champignon ; common mushroom ; edible mushroom ; sludge ; toxic elements ; wastes ; food quality ; forest biodiversity ; metal elements ; traditional foraging ; wild mushrooms ; mercury ; contamination ; Leccinum ; Y. lipolytica ; CCA-treated wood ; copper stress ; ectomycorrhiza ; morphotype ; metal ; plant ; field ; pot ; inoculation ; Paraisaria dubia ; Zn2+ stress response ; transcriptomic ; metabolomic ; metal ion transport ; microcycle conidiation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on treating the associated comorbidities and complications of cerebral palsy. Increased prescription of technology means that we are treating some comorbidities of cerebral palsy earlier or even pre-emptively. Increased life expectancy, compared with 20 years ago, means that we are also seeing even later complications of cerebral palsy. However, increased access to intensive medical care at home, non-invasive ventilation, and total parenteral nutrition now exist. There is also greater engagement with the perspectives and expectations of parents/carers and children. As society begins to discuss mental health more openly, we are also starting to recognise the significant two-way associations between disability and mental health. Ethical consultation may be warranted when harm with treatment exceeds the benefit. As we prepare children with cerebral palsy for adulthood, there is more thought and discussion around issues such as pain, mental health, quality of life, independence, and participation. Researchers in the field of cerebral palsy have contributed original articles and reviews which help build our evidence base to guide shared decision making.
    Keywords: mental health ; anxiety ; depression ; cerebral palsy ; adolescence ; young adults ; young people ; adolescents ; unmet need ; health services ; physical therapy ; occupational therapy ; fracture ; bone fragility ; mortality ; epidemiology ; age-adjusted mortality rates ; death certificate ; medical education ; severe neurological impairment ; scoliosis ; shared decision-making ; respiratory ; hospitalisations ; antibiotics ; Indigenous ; inequities ; cell therapies ; stem cells ; comorbidities ; outcome measures ; clinical studies ; inflammation ; biomarker ; comorbidity ; scoping review ; co-design ; intervention ; participation ; involvement matrix ; public and patient involvement ; early intervention ; infant vocalisations ; infants ; single-subject research design ; CP ; infant ; stress ; parents ; fathers ; parent–infant interaction ; representations ; epilepsy ; children ; neuroimaging ; seizure outcome ; Sialorrhea ; submandibular duct relocation ; postoperative management ; ultrasound ; piecewise model ; muscle volume ; cross-sectional area ; GMFCS ; upper limb ; sensory function ; bimanual intensive functional therapy ; hand function ; associated impairment ; register ; low- and middle-income country ; hip displacement ; hip surveillance ; adductor-psoas release ; hip reconstruction ; guided growth ; salvage surgery ; disability ; emotion regulation ; atropine ; sialorrhea ; pediatric ; drooling ; sublingual ; developmental disorders ; neurodevelopmental disorders ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 22
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Autonomous vehicles are increasingly prevalent, navigating both structured urban roads and challenging offroad scenes. At the core of these vehicles lie the planning and control modules, which are crucial for demonstrating the intelligence inherent in an autonomous driving system. The planning module is responsible for devising an open-loop trajectory, taking into account a variety of environmental restrictions, task-related demands, and vehicle-kinematics-related constraints, while the control module ensures adherence to this trajectory in a closed-loop manner. This adherence is vital in a range of conditions, including diverse weather scenarios, different driving situations, and in response to potential disturbances such as mechanical failures or cyber threats. In certain contexts, these modules are collectively referred to as 'control', with the planning component considered an open-loop controller. This Special Issue focuses on the latest research trends in planning and control methods for autonomous driving. It comprises 11 papers that cover a broad spectrum of applications, including occlusion-aware motion planning in warehouses, control strategies for articulated vehicles, cooperative trajectory planning for autonomous forklifts, and tracking control for underwater vehicles in the face of disturbances and uncertainties. These contributions collectively underscore the diverse and evolving nature of autonomous vehicle technology.
    Keywords: autonomous vehicle ; infrared positioning ; occlusion-aware path planning ; numerical optimal control ; dynamic programming ; quadratic program ; underground intelligent vehicles ; path planning ; RRT* algorithm ; articulated vehicles ; unmanned driving ; spatial exploration ; hierarchical framework ; deep reinforcement learning ; intrinsic motivation ; obstacle avoidance ; data-driven control ; time delay neural network ; drift control ; autonomous driving ; nonlinear model predictive control ; brain–computer interface (BCI) ; steady-state visual evoked potential (SSVEP) ; electroencephalography (EEG) ; threatening pedestrians ; eye-tracking ; automated vehicle ; trajectory planning ; narrow corridor scene ; space discretization strategy ; articulated tracked vehicle ; adaptive model predictive control ; Hybrid A-star ; trajectory tracking ; kinematics ; improved A* algorithm ; GIS ; open-pit mine ; autonomous truck ; scheduling ; artificial bee colony algorithm ; autonomous forklift ; cooperative trajectory planning ; joint dispatching and planning ; Hybrid A* search algorithm ; artificial neural network ; autonomous underwater vehicle ; tube model predictive control ; path tracking ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TR Transport technology and trades
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  • 23
    Publication Date: 2024-01-08
    Description: This Special Issue delves into the strides made, challenges encountered, and research imperatives within the realm of Industrie 4.0 from both a scientific and practical standpoint. This publication features the voices of Industrie 4.0 pioneers Henning Kagermann and Wolfgang Wahlster, as well as leaders in research and industrial application of smart manufacturing concepts.
    Keywords: Industrie 4.0 ; intelligent manufacturing ; smart factories ; industrial artificial intelligence ; digital twins ; zero-defect manufacturing ; digital ecosystems ; China Manufacturing 2025 ; Industrial Internet ; Cloud Manufacturing ; digitalization ; small-medium enterprises ; new business models ; data democratization ; fourth industrial revolution ; smart manufacturing ; smart factory ; digital transformation ; industry ; sustainability ; sovereignty ; interoperability ; mass customization ; Industry 4.0 ; skills ; competencies ; bibliometric analysis ; survey ; Hungary ; maturity model ; transformation ; methodology ; Industry 4.0 strategy ; socio-technical system ; business transformation ; industrial implementation ; mergers and acquisitions ; knowledge management ; networking ; process management ; informational change ; scarce data ; machine learning ; information fusion ; development of work ; sociotechnical systems approach ; human-oriented work design ; D-SI ; DCC ; digital signature ; calibration ; servitization ; digital factory transformation ; smart services ; IoT ; AI ; internal services ; remote work ; COVID-19 ; investment ; n/a ; digital twin ; digital manufacturing ; multi-agent systems ; data architecture ; Logistics 4.0 ; digital transformation strategy ; urban planning and city operation ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJC Business strategy ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: With the continuous improvement of people's living standards, the concern for food nutrition and safety has gradually increased. Consumers increasingly need to replace synthetic food additives with natural components extracted from food. Polysaccharides, starch, protein, pectin, and fibre are major types of biopolymer components in foods. They not only provide people with energy and nutrition, but are also used in food processing as natural additives due to their gelling, emulsifying, and film-forming properties, etc. They are characterised by high biocompatibility, low cost, and ease of access. Some natural components isolated from raw food materials have some drawbacks, such as low solubility and instability under certain conditions, which limit their application in food processing. Currently, many researchers are focusing on the modification, food technology, and future industry of polysaccharides, starch, protein, etc. These studies help to obtain the changed physicochemical and enhanced functional properties of these components, and further promote their high-value utilization in the food field. This Special Issue brings together 34 articles regarding the latest advances in the properties of polysaccharides, starch, protein, pectin, and fibre in food processing, from the improvements of the physical properties of major food components and biological activity studies to their applications in food preservation.
    Keywords: polysaccharide ; antibacterial activity ; toxicity ; body health ; gut microbiota ; pre-gelatinization ; thermal properties ; rheology ; structural properties ; microstructure ; starch gel ; polysaccharides ; inflammatory bowel disease ; mechanism ; polyphenol oxidase ; kudzu ; thermostability ; thermal inactivation kinetics ; food constituents ; conformation ; dietary fiber ; fermentation patterns ; cyanidin-3-O-glucoside ; polymeric proanthocyanidin ; degree of polymerization ; starch ; pasting ; retrogradation ; digestibility ; hyperlipidemia ; resistant starch ; Bifidobacterium pseudolongum ; gut microbes ; synbiotics ; hemp protein isolate ; (−)-epigallocatechin gallate ; covalent binding ; structural changes ; emulsifying properties ; polysaccharide-based materials ; edible packaging ; cellulose ; hemicellulose ; chitosan ; polysaccharide gums ; Holothuria leucospilota ; fermentation behaviors ; antioxidant activity ; zein ; flaxseed gum ; ultrasound ; complex particle ; Pickering emulsion ; soybean residue ; insoluble dietary fiber ; fermentation in vitro ; colon health ; pea ; protein co-precipitates ; protein blends ; surface hydrophobicity ; surimi ; setting ; water migration ; chemical interactions ; purslane polysaccharides ; selenylation ; RAW 264.7 macrophages ; splenocytes ; immune modulation ; type 2 diabetes ; β-glucan ; molecular structure ; anti-diabetic function ; macronutrient absorption ; enzyme inhibitor ; ovomucoid ; superheated steam ; modification ; allergenicity ; mass spectrometry ; acrolein ; IEC-6 cells ; autophagy ; apoptosis ; carboxymethyl chitosan ; frozen surimi ; myofibrillar protein ; denaturation ; gelling properties ; walnut protein isolates ; oxidation ; structural characteristics ; functional properties ; proteomics ; collagen peptide ; B16F10 cells ; melanogenesis ; tyrosinase ; antioxidant ; pea fiber ; industry-scale microfluidizer ; structure ; quinoa protein ; ultrasounic-assisted extraction ; in vitro digestion ; amino acid content ; nuclear magnetic resonance hydrogen spectroscopy ; Chinese yam ; structural characterization ; oxidative stress ; okara ; prebiotic ; γ-irradiation ; anthocyanins ; stable system ; inclusion complex ; hydrogen bonding ; biological activity ; packaging ; preservation ; gelatin ; mulberry leaf polysaccharides ; miscible system ; zeta potential ; rheological properties ; betanin ; gelatinization ; camelina cake polysaccharide ; carrier ; stabilizer ; purple corn cob ; by-product ; anthocyanin bioaccessibility ; tapioca ; hygroscopicity ; BET and GAB models ; particle size characteristics ; storage stability ; pea protein ; moderate enzymatic hydrolysis ; structure properties ; dual protein ; plant protein ; co-precipitation dual protein ; blended dual protein ; fish sausage ; pre-emulsion ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint showcases a collection of a Special Issue entitled “Soilless Culture, Growing Media and Horticultural Plants”. Within its pages, readers will find an assortment of 22 original papers accompanied by 1 review paper and 1 editorial. Representing a collaborative effort involving by 84 authors from 15 different countries, this Special Issue explores cutting-edge advancements in soilless culture, investigating the interaction between soilless and environmental factors while also exploring their consequential impacts on plant growth and physiology. Additionally, these studies meticulously scrutinize the accumulation of secondary metabolites. The compositions of nutrient solutions and the physical attributes of substrates and mixtures are illuminated through rigorous analyses. Furthermore, a spotlight is placed on the dynamic interactions between microorganisms and plant-growing media. In the near future, climate change and environmental and ecological issues will steer the trajectory of soilless culture systems and the choice of growing media constituents.
    Keywords: biochar ; compost ; climate change ; hydroponics ; growing medium ; life cycle analysis ; organic bioresources ; peat alternatives ; renewable raw materials ; rockwool ; waste ; wood fibers ; soilless culture ; water soluble fertilizers ; vegetables ; Capsicum annuum L. ; Solanum melongena L. ; nutrients ; shape index ; UVR8 ; PPFD ; dose-dependent ; photosynthesis ; chlorophyll fluorescence ; phenolic compounds ; nutrient uptake ; nutrient variation ; simulation model ; sweet pepper ; restricted deficit irrigation ; soil moisture sensors ; nonchemical growth control ; water use efficiency ; peat ; growth ; cabbage ; Brassica ; emergence ; colored sweet peppers ; antioxidant activity ; phenolics ; ascorbic acid ; carotenoids ; solar and ultraviolet radiation ; peat replacement ; particle size ; calcium ; magnesium ; extractable nutrients ; dry weight ; N levels ; elevated CO2 ; open-top chamber ; nutrient transportation ; transpiration ; dilution effect ; Capsicum annuum ; flavonoids ; fluorescence monitoring ; bio-waste utilization ; NO3–N ; plant ; substrate ; container ; production ; growing media ; nursery production ; carbon ; peat moss ; bioenergy ; Solanum lycopersicum ; olive oil waste ; two-phase ; three-phase ; water sludge ; flower bud development ; flower number ; flower quality ; Gerbera jamesonii ; DLI ; urban agriculture ; simplified soilless culture ; conventional agriculture ; irrigation ; soilless substrates ; water ; coconut coir ; initial moisture ; mass wetness ; peatmoss ; pine bark ; wettability ; capillary rise ; container capacity ; capture rate ; available water ; dewpoint potentiometer ; pine tree substrate ; substrate processing ; surface-bound water ; unavailable water ; wood substrate ; organic and mineral substrates and mixtures ; laboratory characterization ; hydraulic properties ; physicochemical properties ; lettuce ; plant nutrient content ; Pelargonium zonale ; low-tech soilless cultivation system ; commercial quality ; plant growth-promoting rhizobacteria (PGPR) ; rhizosphere ; plant factory ; plant quality ; plant yield ; microbiome ; beneficial bacteria ; germination ; nitrate content ; phenolic content ; antioxidant capacity ; microbial community ; nutrient solution concentration ; sweetpotato ; storage root ; leaf abscission ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 26
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint entails descriptions of novel issues and challenges for primary mental healthcare regarding both general and vulnerable populations on a global scale. It is intended for health professionals and all who are interested in mental health care at the primary level.
    Keywords: depression ; sense of coherence ; burnout ; COVID-19 ; nurses ; medication adherence ; mental health nurses ; tacit knowledge ; schizophrenia ; sensory processing sensitivity ; environmental sensitivity ; university students ; nursing ; scale ; somatization ; number of diseases ; coping strategies ; sex ; aggression ; alexithymia ; comprehensibility ; quality of life ; family caregivers ; students ; medical ; psychological problem ; undergraduate ; Saudi Arabia ; n/a ; prospect theory ; applied psychology ; health ; decision making ; behavior ; prevention ; multiple sclerosis ; Beck depression inventory ; anxiety ; fatigue ; mediation ; lawyers ; suicidal ideation ; occupational stress ; loneliness ; perceived stress ; mental health ; work overcommitment ; mental health care ; adolescence ; internalizing/externalizing problems ; social skills ; neurodevelopmental disorders ; filmmaking intervention ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
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  • 27
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Taking into account the increasing general concern related to the necessity of reducing CO2 emissions, a very important aspect of this topic refers to the green energy sector. In this vein, the present Special Issue is focused on the area of Offshore Renewable Energy (ORE). This Special Issue contains valuable works related to ORE.
    Keywords: Romanian nearshore ; EEZ ; ERA5 ; water depth ; energy resources ; offshore wind turbines ; offshore wind ; technical analysis ; economic analysis ; Philippines ; European seas ; sea state conditions ; wind climate ; wave climate ; statistical analysis ; solar farm siting ; assessment criteria ; entropy weight method ; AHP ; TOPSIS ; wave power ; wave energy converters (WECs) ; Galician coast ; SWAN ; wave-energy converter array ; interconnected model ; model predictive control ; hardware-in-the-loop ; wave energy converter (WEC) ; heaving point-absorber WEC ; WEC array ; WECfarm ; physical modelling ; real-time control ; MATLAB-Simulink ; heaving point absorber WEC ; system identification (SID) ; solar radiation ; marine renewable energy ; floating solar panels (FPV) ; sustainability ; wave energy converter ; floating flapping-panel ; slope ; hydrodynamic performance ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: With the development of modern society, environmental pollution and energy shortages have become the focus of attention worldwide. Most of the global energy supplies are generated from fossil fuel, which gives rise to environmental pollution and climate change. Photocatalysis technology, which can directly convert solar energy into high value-added fuel and chemical materials or degrade a wide range of organic pollutants into easily degradable intermediates or less toxic small molecular substances, is regarded as one of the most important ways to solve the global energy shortage and environmental pollution problem. This Special Issue focuses on advanced photocatalytic materials, including but not limited to photocatalytic materials for the treatment of indoor air, photocatalytic bacterial inactivation, photocatalytic hydrogen evolution, photocatalytic oxygen evolution, photocatalytic CO2 reduction, photocatalytic hazardous pollutant removal, the photothermal decomposition of pollutants, photoelectrochemical water splitting, etc. This Special Issue provides a platform for scientists to present their original research on “Advanced Photocatalytic Materials for Environmental and Energy Applications”.
    Keywords: PbBiO2I microspheres ; CQDs ; ionic liquid ; charge separation ; interface ; polycrystalline silicon ; solar cells ; low-high-low ; phosphorus diffusion ; semiconductor ; photocatalysis ; indoor air treatment ; volatile organic compounds ; microorganism ; photocatalyst ; type-II heterojunction ; carrier separation ; photodegradation ; phase engineering ; water splitting ; CO2 reduction ; pollutant degradation ; MoS2 ; SnS2 ; composite catalyst ; visible light degradation ; thermo-photocatalysis ; nickel foam ; Ni-doped TiO2 ; acetaldehyde decomposition ; zinc oxide ; Langmuir–Hinshelwood–Hougen–Watson model ; methylene blue ; titanium dioxide ; anodization ; self-doping ; cocatalyst ; Mo2C ; phosphorus ; doped ; g-C3N4 ; photocatalytic ; mixture of pollutants ; coupling system ; plasma ; synergetic effect ; mineralization ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Three-dimensional printing is among the emerging technologies of our time. While it was previously primarily employed for rapid prototyping, this technology has entered a phase of accelerated production, especially for complicated or small objects. Most recently, novel 3D printing technologies have enabled objects with features at the micro- or even nano-scale to be fabricated. Meanwhile, well-known problems such as the waviness of fused deposition modeling (FDM)-printed parts, the missing long-term stability of some typical printing materials or the reduced mechanical properties of 3D-printed objects persist.This Special Issue focusses on all topics related to the 3D printing of micro-electro-mechanical systems (MEMS), such as novel or advanced features enabled by 3D printing compared to conventional technologies, but also the challenges that continue to exist regarding the application of 3D printing technologies for MEMS and new approaches to overcoming them.
    Keywords: 3D printing ; microelectromechanical systems (MEMS) ; microelectronics ; microfluidics ; microsensors ; microactuators ; inkjet printing ; zinc oxide ; heat treatment ; micro-heater ; semiconductor ; 2D printhead ; thermal inkjet ; thin-film resistors ; digital light processing ; projection micro-stereolithography ; micro beam ; fabrication ; additive manufacturing technology ; powder bed fusion ; surface geometrical parameters (SGP) ; lathe chuck jaws ; polymethylmethacrylate ; additive manufacturing ; fused deposition modeling ; passive ; pipeline ; pressure ; reactive impedance sensor ; structural health monitoring ; wireless ; DNA printing ; flow estimation ; MEMS ; ferrite materials ; magnetic thin films ; strontium ferrite nanomaterial ; relative permeability ; relative permittivity ; thermopneumatic ; micro actuator ; soft bellows actuator ; independent actuation ; polydimethylsiloxane ; standalone ; aerosol jet printing ; dielectric ; etching ; polyvinyl alcohol (PVA), polymers ; sacrificial material ; micro-electro-mechanical-system (MEMS) ; lithium niobate microring resonator ; silicon nitride waveguide ; photolithography assisted chemo-mechanical etching ; colorimetric device ; organophosphorus pesticide residues ; LCD mask photo-curing ; PolyJet 3D printing ; fidelity of 3D printing ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: A high demand for metals (cobalt, copper, gold, lithium, nickel, tin, vanadium, etc.) has been recorded for the past several decades, and this demand is expected to increase even further in the coming decades as the world moves to low-carbon technologies based on renewable energy sources (RESs) and electric vehicles (EVs) and away from the heavy use of fossil fuels. To meet the high forecasted demand, unconventional sources of metals such as low-grade complex ores, seafloor massive sulfides (SMSs), and wastes (e.g., tailings, metallurgical residues, and electronic wastes (e-wastes)) have become very important sources of metals; moreover, these metals should be extracted in a sustainable manner without negatively impacting the environment. This Special Issue focused on recent advances in the sustainable production of metals from the above-mentioned unconventional sources.This reprint is a compilation of a Special Issue of Minerals, “Sustainable Production of Metals for Low-Carbon Technologies”, where 13 papers contributed by experts in the area were published. Papers published in this Reprint cover a wide range of topics, including mineral processing (gravity concentration, magnetic separation, and flotation), hydrometallurgical techniques (leaching, solvent extraction, and cementation) to extract minerals/metals from primary and secondary resources. All the papers are of high scientific value and will be of great interest to readers of Minerals.
    Keywords: flotation circuit ; gold ore ; diagnosis ; optimization ; mass balance ; process simulation ; printed circuit boards ; heat treatment ; strength ; liberation ; Cu recovery ; physical separation ; ferronickel slag ; sulfuric acid leaching ; light magnesium oxide ; rare earth elements ; magnetic separation ; upgradation ; Khalzan Buregtei deposit ; NiMH batteries ; rare earth metals ; leaching ; solvent extraction ; precipitation ; gold ; cementation ; galvanic interaction ; aluminum ; activated carbon ; kinetics ; ammonium thiosulfate solution ; mass transfer ; fluorine ; occurrence ; removal ; gravity-flotation separation ; lignite ; lead ; zinc ; Al metal powder ; zinc plant leach residues ; flotation ; copper sulfides ; tailings ; carrier flotation ; flocculation ; oil agglomeration ; complex sulfide ores ; sphalerite ; anglesite ; extraction ; lithium ion battery ; recycling ; carbothermic reduction ; graphite ; porphyry copper deposits ; chalcopyrite ; pyrite ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTU Mining technology and engineering
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue provides an update on the state of the art and current trends in polymeric drug delivery systems specifically designed for improving drug bioavailability. The multiple contributions received further strengthen the role of polymers in modern drug delivery and targeting, illustrating the different approaches possible and unveiling what the future may bring.
    Keywords: Histoplasma capsulatum ; PLGA ; Itraconazole ; macrophage ; functionalized nanoparticle ; F4/80 receptor ; rutin ; nanocrystals ; anti-inflammatory ; hydroxypropyl beta-cyclodextrin ; nanoparticles ; budesonide ; chitosan ; colon delivery ; eudragit ; pellets ; ferrisilicate ; PEG ; insulin ; encapsulation ; diabetic mellitus ; polypeptides ; drug delivery ; doxorubicin ; cancer ; topology of poly-l-cystein ; antimicrobial ; antifouling ; pH sensitivity ; zwitterionic polymers ; gamma radiation ; copolyester ; SPION ; cysteine ; bioconjugation ; and enzymatic release ; polymeric nanoparticles ; drug delivery and targeting ; ocular posterior segment ; oxidative stress ; retinal degeneration ; nerve growth factor ; peanut agglutinin ; zebrafish ; molecular dynamics simulation ; interaction energy ; hydrogen bonding ; solid dispersion ; hot melt extrusion ; amorphous formulation ; tacrolimus ; sucrose acetate isobutyrate ; amorphous solid dispersion ; dissolution ; stability ; pharmacokinetics ; phytomedicine ; nanosponges ; lactoferrin ; bioavailability ; MDA-MB-231 cells ; caspase-3 ; cyclin-D1 ; dendrimers ; Janus nanoparticles ; biocompatibility ; nanoformulation ; pharmaceuticals ; 3D printing ; hybrid scaffold ; polycaprolactone ; vancomycin ; mesenchymal stem cells ; tissue engineering ; drug delivery systems (DDSs) ; osteomyelitis ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The fatigue of metallic materials stands as a pivotal challenge in engineering applications. Exploring the fatigue damage mechanism and fatigue life prediction of metallic materials is of paramount importance. This reprint includes articles that explore relevant topics, and they are intended for academic researchers, engineers, and students seeking a comprehensive understanding of the recent advancements in this field.
    Keywords: 7075 aluminum alloy ; outdoor exposure ; actual marine atmosphere ; pre-corrosion ; fatigue ; fretting fatigue ; digital image correlation ; relative slip ; tangential contact stiffness ; planetary transmission ; hierarchical analysis ; finite element method ; reliability modeling ; fatigue test ; nickel-based superalloy ; non-unified constitutive models ; creep-fatigue ; cyclic softening ; stress relaxation ; 2D-EBSD mapping ; intragranular misorientation ; KAM and GROD ; isotropic linear evolution ; mesoscopic plastic strain ; 3D polycrystalline plasticity model ; nickel-based alloy GH4169 ; complex stress state ; biaxial fatigue ; fatigue crack behavior ; phase field methods ; fatigue fracture ; performance improvement strategies ; rails ; rail steel ; reutilization ; fatigue life ; rail reliability ; crack ; geometric factor ; support vector regression ; pilot plant ; shape optimization ; flow guide disk ; vent hole ; design optimization ; fatigue crack initiation ; short crack ; Neuber’s rule ; strain energy density (SED) ; finite element analysis (FEA) ; TRIP steel ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: The reprint "Comprehensive Research in Earthquake Forecasting and Seismic Hazard Assessment" is a collection of articles dealing with various aspects of the physics of seismic processes, earthquake forecasting, and the search for their precursors. All published articles can be roughly divided into three unequal groups according to the number of articles presented. The first group includes theoretical and methodological articles. The second group includes articles confirming one or another model of seismicity behaviour in anticipation of a strong earthquake. Finally, the third and most numerous group of articles consists of those analysing the results of long-term observations of the behaviour of various geophysical fields. We are confident that each of these articles will find an interested reader, and that the collection as a whole deserves the attention of representatives of the scientific community concerned with the problem of earthquake forecasting and the search for their precursors.
    Keywords: earthquake forecasting ; strain rates ; multiplicative hybrid models ; reverse testing ; spatial distribution ; atmospheric electric field ; earthquake precursors ; radon concentration ; earthquake interevent times ; Greek seismicity ; temporal correlations ; statistical distributions ; earthquake prediction ; infrared remote sensing ; multi-channel ; pre-seismic anomaly ; relative power spectrum ; connected region ; seismic noise ; time series ; singularity spectrum ; wavelet analysis ; spectral measure of coherence ; Kamchatka Peninsula ; earthquake ; source deactivation ; logistic equation ; nonlinear diffusion equation ; Omori epoch ; round-the-world echo ; mirror triad ; PGA ; PGV ; return period ; PSHA ; stochastic seismic hazard assessment ; earthquake preparation ; areas of increased shear deformations ; mathematical simulation ; rock deformation ; acoustic emission of near-surface rocks ; apparent resistivity ; correlation ; earthquakes ; magnetotellurics ; electromagnetic signals ; electromagnetic anomalies ; aftershocks sequences ; Tsallis entropy ; interevent times ; power-law scaling ; complexity ; Antarctic Peninsula ; Seymour–Marambio Island ; Orca submarine volcano ; numerical modelling ; earthquake simulator ; statistical methods ; earthquake clustering ; northern Adriatic sea ; statistical seismology ; numerical modeling ; probabilistic forecasting ; time-series analysis ; wavelet-based entropy ; wavelet-based Donoho–Johnston index ; correlations ; day length ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions, and liposomes, have been extensively studied to improve drug delivery through different administration routes. The main advantages linked to these systems are the ability to protect, transport, and control the release of lipophilic and hydrophilic molecules (either small molecular weight or macromolecules); the use of generally recognized as safe (GRAS) excipients that minimize the toxicity of the formulations; and the possibility to modulate pharmacokinetics and enable the site-specific delivery of encapsulated payloads. In addition, the versatility of lipid-based nanosystems has been further demonstrated through the delivery of vaccines, protection of cosmetic actives, or improvement in the moisturizing properties of cosmetic formulations. Currently, lipid-based nanosystems are well established, and there are already different commercially approved formulations for different human disorders. This success has actually paved the way to diversifying the pipeline of development, upon addressing unmet medical needs for several indications, such as cancer; neurological disorders; and autoimmune, genetic, and infectious diseases. This Special Issue aims to update readers on the latest research on lipid-based nanosystems, both at the preclinical and clinical levels.
    Keywords: design of experiment ; porcine mucous membrane ; ophthalmic tissues ; permeation ; nanostructured lipid carriers ; gentiopicroside ; phospholipid complex ; self-nanoemulsion drug delivery system ; oral bioavailability ; pharmacokinetics ; antioxidants ; marine bio-waste ; bioactive compounds ; neurodegenerative diseases ; NLC ; solid lipid nanoparticles ; SLN ; intranasal administration ; nose-to-brain ; exosome ; drug loading ; exosomal delivery ; large-scale production ; lipid nanoparticles ; mucoadhesion ; ocular bioavailability ; surface modification ; liposomes ; baricitinib ; JAK-inhibitor ; transepidermal delivery ; skin permeation ; lipid NPs ; breast cancer ; siRNA delivery ; gene silencing ; personalized therapy ; bimatoprost ; central composite design ; glaucoma ; HET-CAM test ; solid lipid nanoparticles (SLNs) ; perillyl acid ; biodistribution ; empty lipid nanoparticles ; reactogenicity ; xenobiotics ; ionizable lipids ; isoniazid ; in vivo pharmacokinetics ; drug release profile ; histopathological toxicity ; mannosylation ; nanocarriers ; Chagas disease ; Trypanosoma cruzi ; in vivo assays ; quality by design ; plumbagin ; diabetes ; in vitro ; niosomes ; levosulpiride ; antidepressant ; acute toxicity ; in vivo imaging ; bioavailability ; cisplatin ; co-encapsulation ; mifepristone ; synergism ; gefitinib ; lipid ; surfactant ; stability ; breast cancer cell ; MTT assay ; anticancer ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Although they play a key role in ecosystem functioning and human life, plants are generally overlooked by policymakers and humans in general. In addition, in recent years, we have been witnessing an increase in biologists unable to recognize even common plants, and the number of plant experts (i.e., botanists) able to identify plants is decreasing. In light of these considerations, the Special Issue "Floristic Studies in the Light of Biodiversity Knowledge and Conservation” was launched in the journal Plants, and eight research articles, two reviews, and an editorial were published in it. It has been possible to publish research from different countries, underlining that the knowledge of the flora of a territory is essential to slow down the effects of anthropic pressure on biodiversity and likewise essential for most of the research activities of modern botany.
    Keywords: correlation ; ecology ; essential oils ; Lamiaceae ; vegetation ; species composition ; richness ; urban areas ; anthropogenic impact ; climate ; anthropogenic habitats ; Caucasus ; Himantoglossum formosum ; human-made habitats ; Orchidaceae ; salep harvesting ; Transcaucasia ; kapok ; Ceiba ; fiber ; sustainability ; Malvaceae ; silk-cotton ; phenotypic plasticity ; mangrove grass ; salt marshes ; coastal habitat ; biodiversity ; bryophytes ; generalist plants ; grassland specialists ; historical monuments ; invasive alien plants ; kurgans ; lichens ; native plants ; alien status ; biological records ; Europe ; Latium ; Mediterranean flora ; Rome ; urban biodiversity ; endemism ; floristic research ; herbaria ; lectotype ; nomenclature ; taxonomy ; halophytes ; edible wild species ; coastal areas ; Salicornia ; Arthrocaulon macrostachyum ; Soda inermis ; Cakile maritima ; Crithmum maritimum ; Reichardia picroides ; Silene vulgaris subsp. tenoreana ; Allium commutatum ; Beta vulgaris subsp. maritima ; Capparis spinosa ; Italy ; IUCN ; morphology ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Molecular toxicology is a field that investigates the interactions between chemical or biological molecules and organisms at the molecular level. In this Special Issue, we focus on the toxic effects and mechanisms of action of chemical and biological molecules, will be of great interest of readers in molecular toxicology and applied pharmacology.
    Keywords: smoking ; inflammatory ; cytokine ; human serum ; GO ; PRRSV ; FT-SPR ; sensitization ; NNK ; nicotine ; cytotoxicity ; genotoxicity ; cytochrome P450 2A13 ; Aspergillus flavus ; aflatoxins B1 ; carcinogen ; Surface-Enhanced Raman Scattering ; colloidal Au nanoparticles ; portable Raman spectrometer ; Euphorbia semen ; Euphorbia factors ; transcriptome ; RNA sequencing ; bioinformatics ; gene structure ; neuroblast differentiation-associated protein AHNAK ; hepatocellular carcinoma (HCC) ; insulin-like growth factor 1 receptor (IGF-1R) ; interactome ; field cancerization ; 8–17 DNAzyme ; gene silencing ; catalysis ; antisense ; chemical modifications ; 6-cyclohexyl methyl-β-D-maltoside ; transduction efficiency ; conditionally replicative adenovirus ; lethal effect ; gene therapy ; PBDE ; immunotoxicity ; macrophage ; reactive oxygen species ; apoptosis ; immune function ; breast cancer ; signature ; aging ; cancer ; nomogram ; immunotherapy ; tumor mutation burden ; doxorubicin ; Toll-like receptor 4 ; cardiotoxicity ; heart ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology::MMGT Medical toxicology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the current context of global change and global interconnectedness, our role in connecting the dots and finding solutions to current and future problems is very important. When talking specifically about the management of forests, we can see its continuous evolution and, more importantly, its adaptation to contemporary challenges. As is well known, forest ecosystems play an essential role in our economy, human wellbeing and global wellbeing. More specifically, one of the main challenges in forest management is represented by the sustainability of resources and need to conserve biological diversity. The best way is to think globally, to find patterns that repeat themselves and to investigate solutions that can help us to prepare a better future. In this regard, we think that it is essential to review papers that present interesting findings that could guide us. The first step was to select 18 articles from a wide range of countries located on three continents, including Brazil, Bulgaria, Ecuador, Germany, Malaysia, Peru, Poland, Romania, Slovakia, and Slovenia. Our main goal was to analyse the regionally specific aspects, as well as general aspects that can be applied worldwide. Using this approach, we narrowed our research to eight sub-domains: natural and human disturbances, genetics, site conditions, tropical forest, peri-urban forest, forest soils, forest reserves, and mountain ecosystems. These articles tackle themes such as peri-urban forests and their impact on urban agglomerations, ecoturism, cultural heritages and practices from local communities, human interventions and best practices.
    Keywords: BDq method ; Eastern Amazon ; degraded tropical forest ; forest restoration ; forest economy ; logging selection criteria ; sustainable forest management ; visual perception ; rainforest ; land use ; aesthetics ; Amazon ; management implications ; black locust ; forest ; germination ; provenances ; seed dormancy ; old growth forests ; gene flow ; molecular markers ; legally protected forests ; noninvasive genetic sampling ; brown bear ; management plan ; residual trees ; logging technology ; silvicultural works ; tree healed wound ; forest gaps ; plant colonisation ; community strategy ; Dinaric fir-beech forests ; Ellenberg values ; whole system approach ; data fusion and integration ; semantic and ontological compatibility ; mountain ecosystems ; ecosystem condition ; remote sensing ; vegetation indices ; climate change reanalysis ; dominant species level forest ecosystem classification ; Norway spruce ; Douglas fir ; beech ; maple ; soil chemical properties ; soil microorganisms ; silver fir ; Romanian Carpathians ; stand productivity ; forest sustainability ; silviculture ; ecology ; management ; risks ; uses ; impact ; competitive strength ; forest management ; nature conservation ; naturalness ; European beech ; species diversity ; invasiveness ; homogenization ; Ophiostoma novo-ulmi ; subspecies ; Ulmus minor ; U. glabra ; U. laevis ; tolerance to DED ; climate ; built-up area ; geographical information systems (GIS) ; native species ; plant diversity ; urbanization gradient ; ecological reconstruction ; bacteria diversity ; sustainable rehabilitation ; climate change effects ; peri-urban forest management ; forest stability ; urban expansion ; greenhouse gas emissions ; forest resilience ; diversity ; four corner ; microscale elevation ; correlation ; elevation effects ; alpha diversity ; Andes ; tourist circuit ; beta diversity ; native plants ; phenology ; species richness ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Innovation in chemical plant design is driving improvements in efficiency, safety, and environmental sustainability. This progress is influenced by factors such as safety standards, environmental regulations, market dynamics, and technological advancements. Innovations encompass process intensification, modular design, automation, data analytics, and sustainability solutions, addressing modern challenges. These innovations have diverse applications, spanning drug delivery systems, textile technologies, spray drying, extraction, and active packaging. Notably, supercritical fluid-assisted production of liposomes in pharmaceuticals promises improved therapeutic outcomes through meticulous optimization and sustainability. The textile industry sees advancements in natural dyeing and antibacterial properties, while spray-drying and extraction processes enhance product development and sustainability. Integration of remote sensing and microelectronics aids land surface temperature understanding for applications like agriculture and climate change studies. Convolutional Neural Networks benefit material science, facilitating material identification for energy storage and lubrication applications. Techno-economics for gas-to-liquid processes in natural gas are vital for energy and environmental sustainability. The industry's ongoing evolution prioritizes safety, sustainability, and efficiency, relying on innovative approaches and technologies to create safer, more sustainable, and economically viable chemical processes with reduced environmental impact, contributing to a prosperous and sustainable future.
    Keywords: supercritical fluids ; mass spectroscopy ; ultra-high-pressure liquid chromatography ; cytotoxic compound ; phytosterol ; stigmasterol ; supercritical antisolvent ; micronization ; coprecipitation ; biomedical field ; drug delivery ; Wendita calysina ; burrito ; supercritical fluid extraction ; fractional separation ; D-carvone ; anticancer ; antimicrobial ; liposomes ; carbon dioxide ; high pressure systems ; antibiotics ; lutein ; Weibull model ; techno-economic analysis ; GtL ; Fischer–Tropsch ; ASPEN–Python ; Monte Carlo simulation ; pharmaceutical applications ; biomedical ; graphite ; classification ; transfer learning ; focal loss ; convolution neural network ; supercritical fluid impregnation ; electrospinning ; solvent casting ; antioxidant packaging ; materials optimization ; Landsat 8 LST product ; MODIS ; spatiotemporal fusion ; validation ; electroless nickel-electroless palladium-immersion gold ; Sn-58Bi ; ball grid array ; intermetallic compound ; deep eutectic solvent ; sustainable chemistry ; antioxidant activity ; Euterpe edulis ; experimental design ; spray drying ; agglomeration ; multiple nozzles ; single nozzle location ; air-atmospheric plasma ; mordant ; natural dye ; cotton ; antibacterial activity ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The topics covered in this Special Issue range from breastfeeding and early-life nutrition to effects on microbiota, infection, allergy, asthma, and the mechanisms of immunomodulation via (the early introduction of) nutrition on infections and the development of (food) allergies.
    Keywords: diet ; pregnancy ; cord blood ; fatty acids ; n-3 PUFAs ; n-6 PUFAs ; arachidonic acid ; phospholipids ; atopic eczema ; NICE birth cohort ; multi-allergen ; early introduction ; food allergy ; safety ; efficacy ; prevention ; allergic sensitization ; foetal immune ontogeny ; gene/environment interactions ; asthma ; eczema ; maternal diet ; PUFAs ; vitamin D ; Mediterranean diet ; microbiome ; breastfeeding ; functional gastrointestinal disorder ; partial hydrolysate ; peptide ; protein ; infancy ; childhood ; immune development ; probiotic ; microbiota ; allergy ; atopic dermatitis ; breastmilk ; house dust mite ; Der p 1 ; Asthma ; total IgE ; atopy ; sensitization ; oral tolerance ; early food introduction ; milk protein ; cow’s milk allergy (CMA) ; maternal atopy ; epigenetics ; pediatric asthma ; cohort study ; immune complex ; trained immunity ; RSV ; bovine IgG ; preF protein ; cow’s milk allergy ; allergen ; hypoallergenic infant formula ; n/a ; IgA deficiency ; selenium deficiency ; zinc deficiency ; recommended dietary allowances ; immune system ; allergen molecules ; milk allergen micro-array ; peptides ; anaphylaxis ; milk tolerance ; diagnosis ; IgE sensitization ; children ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint serves as an introduction to the groundbreaking research work that explores the remarkable advancements in biosensor technology and its profound impact on the fields of biomedicine and environmental research. It aims to elucidate the subject's scope, provide future research directions, and highlight potential applications. This reprint is dedicated to the scientific community, researchers, and professionals seeking to expand their knowledge of biosensing. We express our gratitude to all those who have supported and contributed to this scientific endeavor.
    Keywords: live-cell immunoassay ; topographic micropatterns ; on-chip cytokine detection ; nasopharyngeal cancer ; integrated microfluidics ; retinol-binding protein 4 ; type 2 diabetes mellitus ; aptasensor ; colorimetric ; gold nanoparticles ; diagnosis ; biosensing ; fluorescent probe ; AIE ; RNA ; CAG repeats ; nucleic acid aptamer ; DNA and RNA Capture-SELEX ; small molecule contaminant ; characterization ; aptamer ; biosensing applications ; microfluidic ; impedance biosensor ; electrical impedance flow cytometer ; electrochemical impedance spectroscopy ; metal nanoparticles ; immunosensor ; MXene ; MoS2 ; graphene ; MOF ; biomarkers ; graphitic carbon nitride ; black phosphorous ; 2D-LDHs ; boron nitrides ; graphdiyne ; metal–organic frameworks ; luminescence ; surface-enhanced Raman spectroscopy ; multiplexed detection ; polymer dots ; biosensors ; fluorescent probes ; semiconducting polymers ; molecular imaging ; DNA sensor ; silver ion detection ; minidumbbell ; non-B DNA ; C·C mismatch ; cTnI ; PEC immunosensor ; bismuth vanadate ; bismuth sulfide ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This compilation of scientific work delves into innovative wastewater treatment technologies, focusing primarily on the development and optimization of novel catalysts for the effective removal of pollutants. Covering a range of catalysts, including precious metals and nanomaterials, the research offers new insights into cost-effective and efficient pollutant removal methods. Aimed at environmental scientists, engineers, and policymakers, this publication represents a significant contribution from top researchers in the field. It serves as a key resource for those looking to understand and apply the latest advancements in wastewater treatment.
    Keywords: nanohybrid filter ; photoelectrochemical filtration ; carbon nanotubes ; MIL-101(Fe) ; tetracycline ; electrocatalytic oxidation ; anode materials ; Magnéli phase ; titanium oxide ; wastewater treatment ; iron-bearing attapulgite ; heterogeneous Fenton ; granular catalyst ; rhodamine B ; peracetic acid ; advanced oxidation ; reactive dyes ; aniline ; polyvinyl alcohol ; carbon dots ; photocatalysis ; graphitic carbon nitride ; bismuth phosphate ; tetracycline hydrochloride ; electrochemistry ; octogen ; wastewater ; hydroxyl radical ; toxicity ; catalytic membrane reactor ; noble metal catalyst ; molybdenum disulfide ; water purification ; nanoscale zero valent iron ; Cr(VI) ; adsorption kinetics ; mechanism ; modification ; nitrogen dope ; biochar ; peroxymonosulfate ; KOH activation ; bisphenol A degradation ; antibiotics ; catalytic ozonation ; emerging contaminant ; Co-Mn/CeO2 ; norfloxacin ; anode ; metal oxide ; electrolysis ; refractory pollutant ; carbon ; new biochar ; compound material ; organic pollutants ; biochar/zero valent iron ; Ti/Sb-SnO2/PbO2 electrode ; copper-containing wastewater ; active granule doping ; electrocatalytic activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Often, a project's sustainability is centred on building services and energy, but we need to have a comprehensive view of how we integrate deeper sustainability. Traditionally, we have neglected embodied carbon generated during building construction, which has led to significant carbon emissions over the last few decades, causing global warming and other related problems. The aim of this Special Issue was to collect the results of research and practice experiences in sustainable building structures, made from steel, concrete, timber, and other composite materials. Dr Roy and Dr Ananthi warmly invited authors to submit their papers for potential inclusion in this Special Issue of “Sustainable construction using steel, concrete, timber, and other composite materials”, in the journal of Journal of Composites Science.
    Keywords: ground waste tire rubber ; hollow concrete brick ; fractal ; finite element analysis ; compressive strength ; acoustic absorption ; eco-sustainability ; glass-fiber-reinforced polymer (GFRP) rods ; concrete slab ; high-volume fly ash ; moment–curvature ; ductility ; SFRC (steel-fiber-reinforced concrete) ; conventional RCC slab ; plastic hinge length ; repeated loading and composite material ; glass-fibre-reinforced polymer (GFRP) sheets ; flexural behaviour ; cracking behaviour ; load–deflection ; carbon footprint of cement ; bagasse ash composites ; green concrete ; pozzolanic ; sustainable construction ; pultruded glass-fiber-reinforced polymer ; engineered cementitious composite ; cyclic loading ; steel fiber reinforced concrete beam ; carbon fiber mesh ; jacketing ; monotonic loading ; HDPE ; quartz sand ; bitumen ; compression testing ; water absorption test ; efflorescence test ; self-sensing ; reinforced concrete beam ; mortar ; fibre ; electrical resistance ; carbon fibre ; electrically conductive filler ; brass fibre ; transfer learning ; crack detection ; concrete wall ; convolutional neural network ; structural health monitoring ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint, entitled “Application of data-driven method for HVAC System”, is dedicated to providing an overview of the latest achievements in the application of data-driven methods for HVAC systems. Topics of interest include, but are not limited to, the following: fault detection and diagnosis of HVAC systems; energy consumption prediction; model predictive control; data mining and analysis of HVAC systems; data mining and analysis of building environment; energy conservation; energy saving.
    Keywords: indoor air quality ; high occupancy rate ; natural ventilation ; university building ; intelligent packaging ; temperature ; humidity ; supply chain ; food waste ; food quality ; food preservation ; transportation ; grain bin ; PCM ; phase change temperature ; energy saving ; PCM latent heat ; mobile public toilets ; thermal environment ; public health security ; mechanical ventilation ; aerosol transmission risk ; underground commercial buildings ; field measurement ; air distribution optimization ; M-cycle ; evaporative cooling ; solid desiccant ; humidification–dehumidification desalination ; water production ; load data analysis ; demand side management (DSM) ; rural home hotels ; cluster control strategy ; PCM storage ; air conditioning system ; pattern recognition ; clustering ; correlation analysis ; defrosting operation mode ; low-carbon substation ; climate zones ; envelope thermal design ; window to wall ratio ; shape factor ; chillers ; fault diagnosis ; fusion ; residual ; data ; air-conditioned bed system ; heat conduction heating ; convection heating ; thermal comfort ; energy conservation ; genetic algorithm ; existing office parks ; whole life cycle ; cost benefits ; carbon reduction ; retrofit ; relative humidity ; CO concentration ; CO2 concentration ; cooking procedure ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 45
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: References to community interests appear from time to time in scholarly writings in the field of international relations and international law. The concept of community interests refers to interests protected by international law binding either all or a group of states and go beyond the delimitation of a sovereign sphere of influence. In the literature, there are existing examples of research, such as in books and journal articles, that consider the various manifestations of what has been described as “community interests” in many areas regulated by international law, including natural resources, global markets, human rights, and the use of force, and observe how law has evolved from a legal system based on more or less specific consent and aimed at promoting the particular interests of states, to one that is more generally oriented towards collectively protecting common interests and values. However, this topic has not been thoroughly researched, meaning that there is a huge gap in the existing literature, particularly in the context of ocean governance and sustainability. This Special Issue attempts to fill this gap, so as to attract more studies on this important topic in academia.
    Keywords: China ; Marine Environment Protection Law (MEPL) ; daily penalty system (DPS) ; realistic obstacles ; future proposals ; maritime dispute ; international conciliation ; continental shelf ; system effects ; Arctic governance ; Arctic sustainable development ; international law ; China’s role ; Arctic cooperation ; globalization ; international fisheries law ; international fisheries organisations ; fish products ; high seas fisheries ; precautionary approaches ; International Seabed Authority ; deep seabed mining ; exploitation regulations ; multi-subject participation ; environmental impact assessment ; environmental management and monitoring plans ; regional environmental management plan ; marine economy ; sustainability ; indicator system ; Yangtze River Delta ; entropy value method ; maritime security ; human security ; sustainable development ; ocean community ; positive-sum mentality ; South China Sea ; illegal ; unreported and unregulated (IUU) fishing ; maritime Silk Road ; Agreement of Port State Measures (PSMA) ; Anthropocene era ; UNCLOS ; marine environmental protection ; anthropogenic underwater noise ; ocean governance ; marine pollution ; high-seas MPAs ; BBNJ Agreement ; sustainable management ; sustainable fishing ; SDG 14 ; traditional fishing rights ; law of the sea ; policy exit ; international law of climate action ; international investment protection ; linguistic entanglements in the law ; offshore wind energy ; ocean renewable energy ; coastal states ; debt relief ; state responsibility ; climate debt ; sovereign debt ; renewable energy transition ; economic sustainability ; environmental sustainability ; heavily indebted poor countries ; n/a ; bic Book Industry Communication::L Law
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  • 46
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue reprint includes one review and fifteen research articles. The review by Palyanova et al. (2023) summarized the available information on the palladian gold and proposed classifying the types of deposits based on the fineness, content, and set of impurities in palladian gold and minerals intergrown with it. Fifteen articles focused on the typomorphic features of native gold from gold deposits in Russia, India, Chile, Scotland, and Canada. This Special Issue aims to identify and generalize the reasons for variations in the compositions of native gold. I hope all the articles in this Special Issue will be helpful and valuable resources for anyone who is interested in native gold and gold deposits. I thank the Authors and Reviewers for their efforts and contributions. I am also grateful to the Editor-in-Chief, Editors and Assistant Editors of Minerals for their help.
    Keywords: geological-industrial types ; ore formations ; typomorphic features of native gold ; gold deposits in the north-east of Russia ; clinopyroxenites ; palladium gold ; platinum group minerals ; chlorite geothermometer ; sulfur isotopic composition ; placers ; gold ; Chile ; gold microchemistry ; gold morphometry ; gold provenance ; Jagpura Au-Cu deposit ; Aravalli Craton ; high fineness gold ; hydrothermal magnetite ; fluid inclusions ; IOCG-IOA type: IOCG-Co (reduced) subtype mineralization ; placer gold ; internal structures ; stages of ore formation ; endogenous and exogenous conditions ; coarse-grained structure ; high-grade shell ; recrystallization ; granulation ; deformation structures ; porpezite ; alkaline-ultrabasic rocks ; Anabar shield ; Siberian Platform ; alluvial gold ; indicator mineral ; compositional studies ; disseminated Au-sulfide mineralization ; orogenic gold deposits ; Yana–Kolyma metallogenic belt ; sulfide microtextures and mineralogy ; stable sulfur isotopes ; mineral chemistry ; source of gold ; typomorphic features ; fineness ; internal structure ; Anabar placer area ; hydrothermal-metasomatic formations ; K-feldspathization ; jasperoids ; ore mineralization ; fault zone ; ore gold ; sulfides ; gold mineralization ; metasomatites ; bismuth ; tellurides ; uytenbogaardtite ; bismoclite ; cervelleite ; native gold ; supergene gold ; the Spokoininsky cluster ; the Aldan-Stanovoy gold province ; the Aldan shield ; Pd,Hg-rich low-fineness gold ; Au-containing potarite ; substitution structure ; Itchaivayam mafic–ultramafic complex (Kamchatka, Russia) ; placer ; typomorphysm ; linear weathered crust ; Sukhoi Log deposit ; gold–sulfide–quartz (gold–arsenic) and gold–sulfide formations ; Polar Urals ; Manitanyrd ridge ; ore occurrences ; ore mineralogy ; sulfur isotopes ; palladian gold ; Pd,Cu,Ag,Hg-bearing gold ; Au-Pd ; Au-Pd-Ag ; Au-Pd-Cu ; Au-Pd-Hg ; Au-Pd-Ag-Cu ; Au-Pd-Ag-Hg ; Au-Pd-Ag-Cu-Hg systems ; minerals in association ; PGE and gold deposits ; T,P,X-conditions of ore formation ; Au-Pd mineralization types ; detrital gold ; gold alloy composition ; mineral inclusions ; indicator minerals ; gold deposit types ; British Columbia ; brannerite ; uranium mineralization ; Ozerninsky ore cluster ; Western Transbaikalia ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning
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  • 47
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue addresses recent advances in the research of plant-derived natural products, their mechanisms of action and how they can influence health and disease. Plant-derived natural products have been well known since antiquity due to their beneficial effects on human health, and since then, they have attracted the interest of the scientific community, leading to the identification, isolation and quantification of their compounds and research on their biomedical properties. They have been found to be rich in phytochemicals, such as terpenes and phenolic compounds, with proven antioxidant, anti-inflammatory, antimicrobial, antitumor and prebiotic properties, and therefore, they have been suggested as potential candidates for the therapeutic management of several chronic diseases. Some of them include inflammatory bowel disease, diabetes, non-alcoholic fatty liver disease, arthritis and cancer, in which inflammation, oxidative stress and dysbiosis mechanisms are implicated. Furthermore, given the increased economic burden, the side effects and the low compliance rates of patients who receive standard medical treatments, plant-derived natural products could possibly serve as adjunct therapeutic agents for chronic diseases.
    Keywords: plants ; natural products ; free radicals ; inflammation ; medicinal ; caffeic acid ; antibacterial ; antifungal ; antioxidant ; anticancer ; juglone ; Juglans regia ; mogrol ; mogroside ; phytochemical ; pharmacology ; osteoporosis ; antiobesity ; anti-inflammation ; neurodegenerative disorders ; anticancer agents ; aromadendrane ; bryophytes ; cytokinesis inhibitor ; Plagiochila species ; plagiochilins ; analgesic activity ; traditional medicine ; wound healing ; colon carcinogenesis ; 1,2 dimethylhydrazine ; hesperetin ; capecitabine ; Jatropha tanjorensis ; Fraxinus micrantha ; HPTLC ; anti-obesity activity ; high-fat diet model ; histological ; Alzheimer ; acetylcholinesterase inhibitors ; Euonymus laxiflorus Champ. ; bioactive compounds ; medicinal plants ; P. lentiscus ; GC/MS ; HPLC-DAD ; antioxidant activity ; antibacterial activity ; antifungal activity ; extract ; molecular docking ; Artemisia arborescens ; Artemisia inculta ; phenolic compounds ; terpenes ; trace metals ; antioxidant capacity ; Eurycoma longifolia Jack ; anti-inflammatory ; antinociceptive effect ; antipyretic effects ; gastroprotective activity ; gastric ulcer ; Thai traditional medicine ; phytochemicals ; inflammatory bowel disease ; gut microbiota ; Mastiha ; Curcumin ; Boswellia serrata ; Artemisia absinthium ; lipidomic profile ; Tulsi ; Ocimum sanctum ; ischemic stroke ; photothrombotic ischemia ; medicinal plant ; n/a ; bic Book Industry Communication::M Medicine
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  • 48
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies.
    Keywords: multi-beam micromachining ; beam splitting ; invar ; shadow masks ; OLED ; nanosecond laser ; direct laser interference patterning ; design of experiments ; central composite design ; morphological filtering ; surface texture homogeneity ; micro structuring ; bearing steel ; dual laser beam processing ; excited state absorption ; semiconducting thin films ; stimulated emission depletion ; femtosecond laser ; silicon ; amorphization ; crystallization ; spectroscopic imaging ellipsometry ; transmission electron microscopy ; atomic force microscopy ; laser ablation ; ultrafast ; re-deposition ; fs-laser writing ; waveguides ; element redistribution ; Soret effect ; diffusion competition effects ; ultra-short pulses ; double pulses ; burst processing ; MHz bursts ; GHz bursts ; X-ray emission ; micromachining ; dose rate ; X-ray spectrum ; ultrafast laser ; laser ; ultrashort pulse ; plasma ; X-ray ; Bremsstrahlung ; resonance absorption ; burst ; bi-burst ; beam shaping ; squared top-hat ; fs-laser ; laser surface structuring ; laser-induced periodic surface structures ; micro-channels ; glass ; ultrafast laser processing ; Bessel beam ; X-ray emission hazards ; ultrashort pulsed laser ; radiation protection ; industrial applications ; protection housing ; ambient dose rate ; pulsed laser ; laser micromachining ; mechanical shutter ; solenoid shutter ; electro-optic modulator shutter ; opening time ; lifetime ; X-ray energies ; X-ray dose rate ; laser printing ; laser-induced forward transfer (LIFT) ; digital manufacturing ; additive manufacturing ; printing of materials ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 49
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Landscapes and cultural heritage have faced many challenges over time, including modifications and degradation that appear with time, overlaps with other challenges not previously observed, and the influence of cities and management. One of the most visible and globally discussed challenges is climate change. Therefore, there is an urgent need to launch initiatives to tackle climate change and other current challenges from the perspective of landscape and cultural heritage protection. This Special Issue presents selected papers of studies conducted in relation to the 28th Conference on the Series of Garden Art and Historical Dendrology entitled “Climate Change and Current Challenges for Landscapes and Cultural Heritage” that was held on 28 and 29 October 2021. This collection serves as a platform for the exchange of experiences among researchers from different scientific domains.
    Keywords: nature reserves ; landscape fragmentation ; north–south transitional zone ; spatial differentiation ; Qinling–Daba Mountains ; habitat quality ; water dams ; Krakow fortress ; climate change ; environmental management ; cultural heritage conservation ; urban densification ; prefabricated housing estates ; spatial devastation ; protection of urban layout ; Cracow ; climate change mitigation ; cultural heritage ; urban renewal ; urban parks ; therapeutic landscapes ; climate resilience ; vernacular heritage ; climate narratives ; climate adaptation ; climate stories ; courtyard ; urban green infrastructure ; urban pattern ; supervised classification ; ecosystem services (ES) ; urban cemeteries ; biocultural diversity (BCD) ; urban green infrastructure (UGI) ; questionnaire survey ; Leipzig ; Łódź ; sensory gardens ; urban green spaces ; aromatic herbs ; plant smell memory ; stress ; human wellbeing in urban areas ; restorative environments ; history of gardens ; castle garden ; goosefoot avenue ; star-shaped garden layout ; Austro-Hungarian Empire ; Transylvania as part of Romania ; green infrastructure ; resilience management ; biodiversity ; scenario analysis ; cellular automata model ; historic psychiatric hospitals ; therapeutic landscape ; green therapy ; horticulture therapy ; historical commons ; human cultural heritage ; local development ; landscape values ; rainwater management ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 50
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-24
    Description: This book reprints articles from the Special Issue "Advances in Computer-Aided Technology" published online in the open-access journal Machines (ISSN 2075-1702). This book consists of thirteen published articles. This Special Issue belongs to the "Mechatronic and Intelligent Machines" section. Industry 4.0 is characterized by the integration of advanced technologies, such as artificial intelligence, the Internet of Things, and cloud computing, into traditional manufacturing and production processes. CAx (Computer-Aided Systems) systems are a set of computer software tools used in engineering and product design, covering various stages of the product development cycle. Advanced CAx tools combine many different aspects of product lifecycle management (PLM), including design, finite element analysis (FEA), manufacturing, production planning and product. In connection with the transition to Industry 4.0 concepts, the concept of the digital twin comes to the fore, and existing CAx systems must adapt to this trend. The Special Issue deals with a number of research areas, such as: - New trends in CAx systems; Digital manufacturing; Internet of Things in manufacturing; Simulation of production systems and processes; Systems for advanced finite element analysis; Material engineering; Digitization and 3D scanning.
    Keywords: tensor glyph ; golden section ; vector space ; sandwich ; springback ; Vegter yield criterion ; numerical simulation ; PAM-STAMP 2G ; isotropic hardening law ; kinematic hardening law ; bending ; Bauschinger effect ; machine learning ; artificial neural network ; additive manufacturing ; high precision metrology ; CAD ; predictive model ; ship hull structure ; computer-aided design of structure ; database ; function soft block ; gun drill tool ; deep-drilling technology ; optimization ; tool life ; angle ; digital implant impression ; interimplant distance ; intraoral scanner ; trueness ; sewing machine ; needle bar ; floating needle ; electromagnet ; electromagnetic simulation ; noise reduction ; cycloidal gearbox ; friction ; actuator ; servomotor ; permanent magnet synchronous machine ; fixture design ; machining ; sustainable manufacturing ; process innovation ; complex-shape part ; signal processing ; monitoring system ; laser profiler ; surface roughness ; quality assessment ; non-contact method ; vision-based method ; frequency analysis ; abrasive water jet ; wood plastic composite ; natural reinforcement ; knitting machine ; stroke ; drive ; simulation ; cylinder ; dynamic modeling ; load spectrum reconstruction ; fatigue test ; hydraulic excavator ; n/a ; thema EDItEUR::C Language and Linguistics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Mg alloy is the lightest metallic structural material and possesses the advantages of high specific strength, high specific stiffness, good electromagnetism shield, good damping capacity, good machinability, and easy recycling, etc. Therefore, it has extremely broad application prospects and has drawn considerable interest in the fields of automobile, electronics, electrical appliances, transportation, aerospace, and aviation. In addition, Mg alloys are gradually showing application potential in emerging industries, serving as biodegradable metals in the biomedical field, functional material for hydrogen storage, and so on. This Special Issue (SI), entitled “Research Progress in High-Performance Magnesium Alloy and Its Applications”, presents recent developments and excellent results in the field of Mg alloys, and includes 10 articles and one editorial covering some interesting aspects of the topic.
    Keywords: grain refinement ; high strength and toughness ; {10–12} twin ; Mg-Gd-Y alloy ; multidirectional impact forging ; Mg-Zn-Mn-Ca ; Ca2Mg6Zn3 phase ; corrosion behaviors ; SKPFM ; boride ; MgB2 ; mechanical alloying ; ignition ; combustion ; flame temperature ; magnesium alloy ; biocompatibility ; surface coating modification ; corrosion resistance ; implantable bio-metal materials ; filler material ; welding ; scandium ; microstructure modification ; mechanical properties ; microstructure ; texture ; stretch formability ; high temperature cross-rolling ; annealing ; wire arc additive manufacturing ; cold metal transfer ; Al-Mg alloys ; orthogonal experiment ; Mg-Bi-Ca alloy ; hot deformation ; constitutive model ; dynamic recrystallization kinetics ; Mg alloy ; twinning ; random orientation ; compression ; room temperature ; backward extrusion ; tensile strength ; failure mechanism ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 52
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-31
    Description: Thrombosis is a pathophysiological phenomenon observed in acute and chronic coronary syndrome, stroke, and peripheral artery disease. Exposure of the Tissue Factor (TF) to flowing blood is followed to its binding to other coagulation factors leading to thrombin formation. Together with platelet activation, TF ultimately promotes thrombus formation. Recent advances in platelet pathophysiology have shown that these cells are able to regulate their gene/protein expression, engage in de novo protein synthesis, and release different mediators that may interfere with different cell functions. Several clinical trials have clearly shown the efficacy of anticoagulation and/or anti-platelet aggregation in different thrombotic disorders. Real-world practice clearly indicates that antithrombotic strategies need to be personalized according to patient characteristics. The combination of multiple antithrombotic drugs represents a challenging scenario and was the focus of multiple recent randomized controlled trials, with more still to come. As knowledge about platelets and the coagulation system has substantially evolved within the last few years, so should our approach to antithrombotic treatment; focused on current hurdles of antithrombotic treatments in patients with cardio- and cerebrovascular diseases, starting from the molecular mechanisms involved, proposing practical solutions to compelling clinical scenarios using a pathophysiology-oriented approach on the basis of current clinical evidence.
    Keywords: P2Y12 inhibitor ; monotherapy ; percutaneous coronary intervention ; dual antiplatelet therapy ; high bleeding risk ; high on-treatment platelet reactivity ; randomized controlled trial ; left atrial appendage thrombus ; atrial fibrillation ; stroke ; oral anticoagulant ; cardiovascular diseases ; novel antithrombotic agents ; antiplatelet drugs ; anticoagulants ; hemostasis ; factor XI ; factor XI inhibitor ; thrombosis ; new drugs ; left ventricular thrombus ; anticoagulation ; anterior wall myocardial infarction ; dual therapy ; direct oral anticoagulants ; surface plasmon resonance ; metformin ; matrix metalloproteinase-9 ; plaque instability ; atherosclerosis ; cancer ; acute coronary syndrome (ACS) ; percutaneous coronary intervention (PCI) ; dual antiplatelet therapy (DAPT) ; triple antithrombotic therapy (TAT) ; atrial fibrillation (AF) ; cardiotoxicity ; aspirin ; coronary artery disease ; cerebrovascular disease ; diabetes mellitus ; essential thrombocythemia ; platelet function ; thromboxane ; gastrointestinal bleeding ; enteric-coated aspirin ; cardiovascular prevention ; P2Y12 inhibitors ; acute coronary syndrome ; clopidogrel ; prasugrel ; ticagrelor ; cangrelor ; selatogrel ; zalunfiban ; peripheral artery disease (PAD) ; antithrombotic therapy ; dual pathway inhibition (DPI) ; major adverse cardiovascular events (MACE) ; major adverse limb events (MALE) ; n/a ; thema EDItEUR::M Medicine and Nursing ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Papers collected in the present Special Issue relate to the field of sericulture. They cover different aspects based on a very ancient human agricultural activity, taking into consideration classical agronomic aspects, such as the impact of feeding on silk quality and sericulture in different parts of the world. Nonetheless, cutting edge topics are addressed as well, with papers studying silk as a biomaterial, the silkworm as a model organism, and the possibility of exploring its physiology and the molecular mechanisms that stand behind it with the aid of modern tools such as gene profiling, the CRISPR/Cas-9 system, and -omics sciences.
    Keywords: silkworm ; Bombyx mori ; transcriptome analysis ; RNA-seq ; gene model transcriptional factor ; Cutibacterium acnes ; infection ; antibacterial drugs ; polyamines ; cell cycle progression ; Bombyx mori nuclear polyhedrosis virus ; sequencing analysis ; qPCR ; pathogenicity difference ; maternal mRNAs ; 20-hydroxyecdysone ; pupa ; wandering ; fibroin ; sericin ; chrysalis ; diabetes ; hydrogen sulfide ; transcriptome ; differentially expressed genes ; expression pattern ; silk ; supercritical carbon dioxide impregnation ; nanofiller ; CRISPR-Cas ; silkworms ; genome engineering ; insect biotechnology ; entomology ; sericulture ; agroindustry ; Food and Agriculture Organization of the United Nations ; mulberry ; moriculture ; germplasm preservation ; 16S rRNA gene ; amplicon sequencing ; gut microbiota ; co-expression network analysis ; silk protein ; transcription factor ; Eri silkworm ; pentose-utilizing microbe ; lactic acid bacteria ; probiotic ; Eri culture ; silk fibroin ; SILKBridge® nerve conduit ; performance testing ; biocompatibility ; toxicology ; regulatory requirements ; quality requirements ; control manufacturing ; green material ; biomaterial ; 3D scaffolds ; cancer therapy ; bibliometric analysis ; mulberry silkworm pupae ; nutritional composition ; silk gland ; infection model ; Staphylococcus epidermidis ; insect immune response ; antimicrobial compounds ; glycopeptide antibiotics ; vancomycin ; teicoplanin ; dalbavancin ; mulberry leaves ; chemical composition ; feeding experiment ; bacterial microbiome ; BmNPV ; Bombyx mori L. ; non-timber forest product ; livelihood ; Indonesia ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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  • 54
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This Special Issue, “Mapping Indigenous Knowledge in the Digital Age”, explores Indigenous engagement with geo-information in contemporary cartography. Indigenous mapping, incorporating performance, process, product, and positionality as well as tangible and intangible heritage, is speedily entering the domain of cartography, and digital technology is facilitating the engagement of communities in mapping their own locational stories, histories, cultural heritage, environmental, and political priorities. In this publication, multimodal and multisensory online maps combine the latest multimedia and telecommunications technology to examine data and support qualitative and quantitative research, as well as to present and store a wide range of temporal/spatial information and archival materials in innovative interactive storytelling formats. It will be of particular interest to researchers engaged in studies of global human and environmental connection in the age of evolving information technology.
    Keywords: transdisciplinary research ; knowledge dialog ; participatory mapping ; qualitative analysis ; community-based management ; Dawes ; allotment ; GIS ; map ; automation ; PLSS ; geographic information systems ; reservation ; indigenous ; Standing Rock ; community mapping ; learning community ; natural resources management ; Cyberatlas ; Native Americans ; first nations ; historic cartography ; toponymy ; Indigenous maps ; indigital ; undergraduate education ; native science ; Inuinnait ; Inuinnaqtun ; cybercartography ; digital return ; multi-media cartography ; digital heritage ; native guidance system ; Lençóis Maranhenses region ; Maranhão coast ; traditional communities ; Cybercartographic Atlas ; indigenous mappings ; decolonial cartography ; mythical spaces and indigenous orientations ; sky map ; collaborative work ; Pa Ipai ; Baja California ; Mexico ; mapping ; reconciliation ; art ; digital pedagogy ; reflexivity ; Cybercartography ; GIAMedia ; FOSS ; intercultural literacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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  • 55
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: This reprint addresses the relationship between education and sustainability from various perspectives. The main issues discussed in the 12 collected papers are concerned with (1) the quality of education, (2) SDG policy and implementation, (3) education and societal development, (4) students’ learning, and (5) global experience.
    Keywords: bridging academics ; regional sustainability ; knowledge diffusion ; public–private partnership ; multi-node knowledge link model ; stakeholders ; paradox of Chinese learners ; learning concept ; virtue model ; mind model ; Confucian culture ; mindset intervention ; interaction ; iterative process ; persuasive ; stealthy ; education for sustainable development ; China ; education policy ; sustainable development ; ESD ; SDGs ; sustainability ; higher education ; indicators ; rankings ; assessment ; university rankings ; green universities ; green campus ; education ; learning ; educational innovation ecosystem ; education sustainability ; university-industry collaboration ; Chinese higher education ; digital age ; talents cultivation ; information literacy ; online learning process ; innovation performance ; nature education ; urban residents ; perception ; survey ; sustainable growth ; social-emotional skills ; self-management skills ; solution-focused ; Kids’Skills method ; education partnership assistance ; common prosperity ; balanced and sustainable development ; capacity building ; professional learning communities in interdisciplinary subjects ; teachers’ professional development ; teacher learning ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: This Special Issue highlights fundamental changes to the questions that we can ask about both the recent past and deep time. Delve into the forefront of paleontological research with this Special Issue reprint. Renowned paleontologists from around the world share groundbreaking insights into ancient life on Earth. Discover the latest advances in fossil discovery, analytical techniques, interdisciplinary collaborations, and technological innovations that are shaping our understanding of evolution and the Earth's history. This collection of cutting-edge research is a must-read for scientists, researchers, and enthusiasts interested in the dynamic field of paleontology in the modern era.
    Keywords: REE ; Tyrannosaurus rex ; molecular paleontology ; geochemical taphonomy ; diagenesis ; bone ; protein ; collagen ; Hell Creek Formation ; cuticle ; Eocene ; Fur Formation ; insects ; melanin ; mo-clay ; pigment ; Stolleklint Clay ; structural coloration ; Ølst Formation ; fossil ; dinosaur ; paleoproteomics ; porphyrin ; keratin ; feather ; taphonomy ; degradation ; microbes ; CO2 ; apatite ; paleontology ; China ; history ; 20th century ; 21th century ; paleobiology ; history and philosophy of paleontology ; twenty-first-century paleontology ; paleobiological revolution ; technoscience and global issues ; fossil proteins ; rare earth elements ; soft-tissue preservation ; geochemistry ; soft tissues ; molecular preservation ; Hornerstown Formation ; shallow marine ; glauconite ; hybridization ; introgression ; ancient DNA (aDNA) ; hominin paleontology ; paleoanthropology ; Brachylophosaurus ; Judith River Formation ; ELISA ; RIA ; Venta Micena site ; VM-0 ; VM-1960 ; taxonomy ; morphometrics ; phylogeny ; evolution ; morphological clock ; molecular clock ; biodiversity ; palaeobiogeography ; macroevolution ; primates ; Cercopithecidae ; monkeys ; genotype:phenotype mapping ; dentition ; Equidae ; Equinae ; hipparionini ; protohippini ; equini ; paleoecology ; paleoclimatology ; biochronology ; steroids ; diet ; coprolites ; Gryphaea dilatata ; crystallographic texture ; pole figures ; neutron diffraction ; recrystallization ; thick-walled shells ; molecular taphonomy ; fossils ; preservation ; mass spectrometry ; dinosaurs ; Neanderthal ; Combe-Grenal ; juvenile ; mandible ; periodontitis ; tooth ; tartar ; SEM analysis ; n/a ; terrestrialization ; artrhopods ; Cambrian explosion ; molecular clocks ; palaeontology ; phylogenomics ; teeth ; enamel ; microanalysis ; Purussaurus ; Neoepiblema ; miocene ; ICP-MS ; MEV ; microscopy ; magnetic resonance imaging ; micro-computed tomography ; radiocarbon dating ; DNA barcoding ; synchrotron ; bone remodeling ; elemental analysis ; diagenetic alteration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The World Health Organization recommends the consumption of plant foods instead of animal-origin foods due to their high levels of saturated fat and cholesterol. Consumption of plant products has led to research on the beneficial properties of their components beyond basic nutrients. Vegetable-derived peptides have shown multifunctional effects related to chronic diseases, attracting interest from the food, nutraceutical, and pharmaceutical industries. This reprint highlights studies on various vegetable extracts, such as chestnut, quinoa, amaranth, buckwheat, and Protium heptaphyllum gum resin, which have demonstrated antimicrobial, anti-inflammatory, and cholesterol-regulating properties. Specific compounds derived from plants, such as methyl p-coumarate and lupin protein hydrolysate, have shown effectiveness in reducing inflammation and anxiety, respectively. A vegetable extract of rosemary has been studied for its potential to treat osteogenesis imperfecta. Moreover, this repprint reviews Lycium barbarum berries, essential oils from Annonaceae species, antioxidant compounds, phytosterols, and natural compounds for the prevention and treatment of oral mucositis was discussed. Overall, these studies suggest that vegetable-derived bioactive compounds could serve as new nutraceuticals to prevent and treat a wide range of chronic diseases.
    Keywords: hypercholesterolemia ; gene expression ; HMGCR ; PCSK9 ; PPARα ; enzymatic activity ; molecular docking ; statin ; monacolin ; breu branco ; seed storage proteins ; peptides ; anti-inflammatory ; antioxidant ; trypsin inhibitors ; quinoa ; amaranth ; buckwheat ; in vitro gastro-intestinal digestion ; natural products ; Brazilian species ; essential oil ; applications ; phytosterols ; neurodegeneration ; Alzheimer’s disease ; blood brain barrier ; obesity ; oxidative stress ; dyslipidemia ; diabetes ; enzyme-assisted extraction ; plant material ; phenolic compounds ; oligosaccharides ; prebiotic ; nanocellulose ; nanofibers ; fermentation ; sustainability ; cancer ; drug delivery ; oral mucositis ; treatment ; lupin ; protein hydrolysates ; anxiety ; ApoE−/− ; functional foods ; peptidomics ; rosemary extract ; collagen type I ; unfolded protein response ; autophagy ; proteasome ; skin fibroblasts ; apoptosis ; osteogenesis imperfecta ; asthma ; methyl p-coumarate ; Th2 cytokines ; eosinophil ; NF-κB ; Castanea sativa shells ; Subcritical Water Extraction (SWE) ; antimicrobial activity ; goji berries ; pro-healthy effects ; phenolics ; biological properties ; functional ingredients ; in vitro cultures ; Ruta montana ; coumarins ; alkaloids ; antibiofilm formation ; antibacterial activity ; antioxidant activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy.
    Keywords: weak detonation ; high activation regime ; nonlinear PDEs ; Fuchsian reduction analysis ; Lorentz transformation ; blow-up ; hot spot ; chemically reactive flows ; nonlinear equations in partial derivatives ; hyperbolic equations ; Bäcklund transformations ; Clairin’s method ; differential relationships ; the Liouville equation ; symbolic calculus ; canonical system of q-difference equations ; q-Euler integral ; multi-term fractional differential equation ; quasilinear equation ; Riemann–Liouville fractional derivative ; defect of Cauchy type problem ; fixed point theorem ; initial-boundary value problem ; deformed numbers ; deformed algebras ; deformed calculus ; nonadditive entropy ; vibration control ; boundary control ; intermediate state control ; separation of variables ; Riemann–Liouville fractional differential equations ; nonlocal boundary conditions ; positive parameters ; positive solutions ; existence ; nonexistence ; Patlak–Keller–Segel systems ; the Cattaneo model of chemosensitive movement ; hyperbolic models ; shock waves ; conservation laws ; constrained Hamiltonian system ; canonicalization ; symplectic method ; numerical simulation ; extended Chebyshev functional ; generalized proportional Hadamard fractional integral operator ; manipulation system ; geometric approach ; noninteraction ; two-phase flow ; Sobolev spaces ; analytic semigroups ; fractional interpolation ; local and global solutions ; seismic tensorial force ; far-field seismic waves ; near-field seismic waves ; seismic mainshock ; quasi-static deformations ; mathematical physics ; Elliott Lieb ; the International Association of Mathematical Physics (IAMP, history and development) ; Letters in Mathematical Physics (LMP) ; history ; God as an (optional) axiom ; metamathematics ; symmetries ; particle physics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: This Special Issue covers manufacturing of a smart polymer composites via choice of ingredients, such as polymer, filler, and additives, as well as their unique composition. It also covers the smart processing of polymer composites, which is influenced by the choice of mixers, processing condition, processing technique, etc.
    Keywords: thermoplastic polyurethane ; expanded bead ; supercritical CO2 foaming ; expansion ratio ; resilience ; hardness ; poly(lactic acid) ; lignin ; maleic anhydride ; chemical modification ; 3D printing filament ; SEBS ; membrane ; water uptake ; impedance spectroscopy ; ionic conductivity ; phlogopite ; natural rubber (NR) ; ethylene-propylene-diene monomer rubber (EPDM) ; mechanical properties ; compatibility ; nylon 6 ; polyketone ; chain extender ; hydrogen bonding ; chain branching ; chain crosslinking ; melt viscosity ; shape memory polymer ; NIR light responsive ; semicrystalline maleated polyolefin elastomer ; polyaniline ; melt blending ; adhesive ; fluorosilicone ; thermal conductivity ; magnesium oxide ; boron nitride ; syntactic foams ; hyperbranched polymer ; polyamide 6 ; hollow glass microsphere ; lubricant ; compatibilizer ; composites ; silica ; silane ; hydrolysis ; interfacial adhesion ; zinc mechanism ; hybrid flame retardant materials ; influence of gypsum ; minimum total heat release ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The eradication of vector-borne diseases is threatened by the limited range of available insecticides, leading, inevitably, to the development of resistance. This is particularly concerning for malaria control, which relies heavily on insecticide-treated nets (ITNs) and indoor residual sprays (IRS). New chemistries are being developed, and innovative deployment of insecticides may play a role in overcoming resistance, either through new types of tools or new means of distribution. A variety of novel product types and vector control strategies are under development and evaluation, which is to be celebrated, but a strong evidence base is needed to guide effective operational deployment decisions. Novel approaches should be supported by robust data collected using appropriate and validated methods to monitor efficacy, durability, and any emerging resistance. This reprint presents original research into developing and characterizing new vector control products, as well as understanding and monitoring insecticide resistance. Review articles explore the impact of insecticide resistance and offer guidance on insecticide choice in the face of pyrethroid resistance. Consensus methodologies are presented, in the form of standard operating procedures (SOPs) designed to be adopted and used to generate reproducible data that can be compared and interpreted across and between studies. It is hoped that this collection of articles offers inspiration and guidance on how consistent data can be generated to inform more effective development, evaluation, and use of new and existing vector control tools.
    Keywords: prallethrin ; insecticide ; spatial treatment ; mosquito fitness ; protection ; pyrethroids ; Aedes albopictus ; Culex pipiens ; life tables ; mosquito ; bite-proof garment ; model ; textile ; non-insecticidal ; physical barrier ; insecticide selection ; out-crossing ; strain authentication ; laboratory screening ; pyrethroid ; pyrethroid resistance ; insecticide resistance ; insecticide resistance management ; vector control ; malaria ; malaria control ; Anopheles ; host-seeking behavior ; insecticide exposure ; pathogen transmission ; Aedes aegypti ; Anopheles gambiae ; ATSB ; Culex quinquefasciatus ; Iroquois ; RNAi ; Saccharomyces cerevisiae ; yeast ; Anopheles mosquito ; fertility ; ovary development ; pyriproxyfen (PPF) ; side-effects ; machine learning ; image classification ; automated identification ; convolutional neural network ; insecticide-treated net (ITN) ; PBO ITN ; synergist ITN ; dual-AI ITN ; insecticide resistance management (IRM) ; method validation ; durability monitoring ; bioinsecticide ; disease transmission ; insecticide-resistance ; mosquito-borne disease ; mosquito control ; natural compounds ; phytochemical ; malaria vector ; insecticide treated nets ; cytochrome P450s ; kdr ; cuticular resistance ; deltamethrin ; imidacloprid ; bifenthrin ; β-cyfluthrin ; etofenprox ; α-cypermethrin ; λ-cyhalothrin ; thiacloprid ; mosquitoes ; Attractive Toxic Sugar Bait (ATSB) ; Attractive Targeted Sugar Bait (ATSB) ; diagnostic bioassay ; resistance monitoring ; insecticide-treated nets (ITN) ; strain characterisation ; method development ; product evaluation ; quality control (QC) ; dual active ingredients (dual-AI) ; bioefficacy ; IRS ; application technology ; broflanilide ; clothianidin ; pirimiphos-methyl ; WHO tube ; WHO tunnel test ; ITNs ; interceptor ; interceptor G2 ; membrane ; human arm ; rabbit ; bioassay ; bio-efficacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Phenolic compounds in food such as fruits, vegetables, wine, spices, and oils have been characterized and their possible effects on human health has been studied in depth. Several technological aspects have also been considered concerning the sustainable extraction of phenolic compounds, the long-term storage effects, and the influence of fermentation and boiling techniques on their properties.
    Keywords: chestnut ; water curing ; non-targeted MS analysis ; antioxidants ; Arecaceae ; polyphenols ; volatile content ; antioxidant activity ; liquid chromatography ; inflammation ; lung ; oxidative damage ; antiviral ; polyphenol ; phenolic acids ; flavonoids ; Vicia faba ; functional food ; green solvents ; biologically active compounds ; selective separation ; medicinal plants ; ultrasonic-assisted extraction ; microwave-assisted extraction ; kombucha ; black tea ; long-term storage ; antioxidant scavenging activity ; total phenolic content ; meat quality ; antimicrobial activity ; C. scolymus ; food quality ; beverages ; health properties ; antioxidant activities ; fibrinogen ; albumin ; rutin ; tannic acid ; resveratrol ; binding properties ; first order ; kinetic modelling ; zero order ; food processing ; herbal tea ; boiling ; EVOO ; vegetables ; phenolic compounds ; thermal treatment ; processing techniques ; bioaccessibility ; bioavailability ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Keywords: cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: In recent years, inorganic oxidic nanomaterials have been extensively investigated for their outstanding properties that allow their use within a large variety of raising fields of interest, ranging from (photo)catalysis to the development of functional nanocomposites. Nanoscopic metal (eventually mixed) oxides are often fabricated following soft-chemistry approaches, characterized by the possibility of favouring specific morphologies, particles dimensions, and surface porosities through different synthetic methods and templating processes. In this context, surface functionalities and reactivity play a major role in the determination of nanomaterials final properties. For this reason, further surface functionalization with specific chemical moieties is often recommended to extend their field of application. This Special Issue, now edited as a book, aimed at extending the comprehension of the mechanisms involved in the synthesis and templating of inorganic oxidic nanomaterials, as well as in their surface functionalization and reactivity. Additionally, this Special Issue aimed at increasing the knowledge on the latest advances of these systems in (photo)catalysis, environmental clean-up processes, energy storage, controlled transport and/or release, biomedicine, sensing, development of smart-materials, stimuli-responsive materials, and nanocomposites. Nanomaterials of interest included: silica, alumina, titania, zirconia, zinc oxide, aluminosilicates, iron oxides, perovskites and titanates, rare earth oxides, and composites. Furthermore, particular attention was dedicated toward studies describing alternative ecofriendly preparation methods.
    Keywords: alumino-silicates ; biomedicine ; ceramics ; clays ; inorganic chemistry ; environmental remediation ; nanomaterials ; porous materials ; mesoporous material ; zero-valent-iron nanoparticles ; methylene blue adsorption ; metal–organic framework ; iridium oxide ; nanostructuration ; IrO2 applications ; IrO2 synthesis ; OER ; C3N4 ; ZnO ; heterojunction ; photocatalyst ; metal oxide nanocomposites ; microstructural analysis ; electrospinning ; polymer substrate ; photodegradation ; LSA 99Mo ; thermodynamic parameters ; solid-phase extraction ; isotherm ; metal oxides NPs ; Ni-Fe-TiO2 nanocomposite ; microstructure ; biocompatibility ; endodontic file ; graphitic carbon nitride ; photocatalysts ; g-C3N4/ZnO ; visible light ; photocatalytic degradation ; inorganic coatings ; functional coatings ; stimuli-responsive polymers ; sol–gel ; antimicrobial ; wear-resistance ; photo-catalytic activity ; UV protection ; calcium oxide-doped carbon nitride nanostructures ; basic fuchsine ; elimination mechanism ; π-π stacking ; magnetic nanoparticles ; magnetite ; solvothermal synthesis ; waste valorization ; green chemistry ; advanced oxidation processes ; experimental protocols ; heterogeneous catalysis ; inorganic thermal activation ; organic pollutants ; perovskites ; physico-chemical characterization ; solution combustion synthesis ; strontium ferrates ; water treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint reviews a crop pest management use for several essential oils and the properties of an excellent lemon (citral) source. Research is reported on the biological properties of enhanced lemon oil along with the human intake of citrus beverages and the less common medicinal mastiha oil. Oils and hydrolates of rosemary and lavender were analyzed by headspace/GC-MS to better define their antibacterial, antioxidant and cytotoxic activities, and yeast particle encapsulation was investigated for the controlled release of bioactive terpenes.
    Keywords: monoterpenes ; mastiha oil ; absorption ; Citrus limon (L.) Osbeck ; essential oil ; citral ; nutraceuticals ; inflammation ; oxidative stress ; terpenes ; yeast particles ; antimicrobial ; anthelmintic ; prodrug ; beverages ; Citrus ; coumarins ; furocoumarins ; polymethoxyflavones ; linear retention indices ; liquid chromatography ; tandem mass spectrometry ; multiple reaction monitoring ; quality control ; Backhousia citriodora ; lemon myrtle ; lemon oils ; geranial ; neral ; iso-citrals ; citronellal ; flavor ; fragrance ; biological activity ; Lavandula angustifolia ; Rosmarinus officinalis ; essential oils ; hydrolates ; chemical analysis ; volatile compounds ; phytochemicals ; synergism ; fractional inhibitory concentration ; insect mortality rate ; phytopathogenic fungi ; insect pests ; pesticide resistance ; fungicide resistance ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The sustainability of water resources worldwide is increasingly imperiled as climate change contributes to the human-induced problems of water supply scarcity and maldistribution. Environmental problems associated with water quality, such as aquifer depletion, land subsidence, the seasonal drying of river flows, waterlogging, the salinization of rivers and groundwater, and human health problems from the excessive use of fertilizers and pesticides will require a radical re-thinking of resource-management policy and new tools to help analysts and regulators craft novel solutions. Over the past several decades, with the advent and rapid progress of computational technology, watershed models have increasingly become important and effective tools for tackling a wide range of water resource and environmental management issues and for supporting regulatory compliance. Statistical and machine-learning methods are being used to support and even supplant more traditional simulation models to improve the estimation of the temporal dynamics and patterns of variability in pollutant concentrations and loads. With the advancements in modeling approaches for water quality, there have also been developments in decision-support tools for water quality management. This reprint describes innovative decision-support approaches from around the world and across sectors that can be applied by stakeholders, government entities, and regulators to reduce environmental pollution and result in cost-effective and sustainable water management strategies.
    Keywords: tree-ring ; flow reconstruction ; pre-development ; estuarine salinity ; salinity intrusion ; water quality forecasting ; decision support ; WARMF ; regression model ; salinity ; irrigated agriculture ; stakeholder involvement ; stream water quality ; CART ; ID3 ; random forest ; bagging ; boosting ; extremely random trees ; Gradient Boosting ; land use factor ; Decision Support System ; water quality forecast ; MLP neural network ; Daubechies 5 wavelet ; long short-term memory network ; hybrid model ; decomposition-and-ensemble ; CE-QUAL-W2 ; EDSS ; SaaS ; irrigation ; agriculture ; policy ; water ; economics ; model ; conservation practices ; decision making ; nutrients ; sediment ; targeting ; water quality ; chemical footprint ; emerging contaminants ; endocrine-disrupting compounds ; footprint calculator ; personal care products ; remote sensing ; geographical information systems ; watershed management ; ambient monitoring ; data collection ; San Joaquin River ; decision support system ; assimilative capacity ; real-time management economics ; drinking water quality ; operational decision-making ; real-time monitoring ; Sacramento-San Joaquin Delta ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: In 2020-2022, much of the world was at risk for catching COVID-19. This reprint, “Crimmigration in the Age of COVID-19,” contributes to understanding immigration during the pandemic. It engages a cross-national and interdisciplinary case-study approach to show how countries carved out exceptions to public health protocols for migrants. In the immigration context a variety of governments weaponized public health protocols to criminalize and exclude migrants. The Trump Administration sadistically misplayed the pandemic at almost every turn. Trump came to power on the backs of migrants, referring to them as murderers and rapists. The intersection of Trump’s COVID-19 and migration policies carved out space for the exceptional dehumanization of migrants in 2020-21. This reprint documents the weaponization of public through crimmigration. Crimmigration is the criminalization of migration and migrants via state-of-the-art surveillance and militarized technologies. During the worst of COVID-19, crimmigration strategies--mandatory detention and harsh exclusions— exacerbated the risk of transmission among migrants. Policies not migrants were to blame here. The ostensibly public health related Title42 actually pushed migrants, already at great risk, into unregulated shantytowns controlled by Mexican drug cartels. Additionally, migrants contended with detention facilities, medium security prisons, that functioned as Petrie dishes for the disease. We hope this reprint contributes to understanding the intersection of public health and crimmigration, and border penologies during these exceptional times.
    Keywords: coronavirus ; immigration detention ; migration enforcement ; detention abolition ; detention ; immigration ; human rights ; healthcare ; access to justice ; crimmigration ; deportation ; return ; COVID-19 ; pandemic ; securitisation ; threat prioritisation ; Australia ; New Zealand ; welfare ; exclusion ; surveillance ; attrition ; incarcergration ; decriminalization ; detention standards ; alternatives to detention ; conditions of detention ; COVID ; racial apathy ; white ignorance ; institutional legitimacy ; governing through migration ; The Netherlands ; discourse ; border practices ; asylum seekers ; economic migrants ; Poland ; pushbacks at the border ; COVID-19 pandemic ; governmental xenophobia ; migrants/refugees ; vaccination ; Greece ; n/a ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The ongoing deployment of 5G networks is a key enabler for realizing upcoming services at scale, including the massive deployment of the Internet of Things, providing communications to support autonomous vehicles, and supporting the realization of smart cities. However, as the limitations of existing approaches become apparent, the need for next-generation technologies is growing, in terms of improving spectral efficiency, increasing network data rates and densification, supporting local/wide area wireless coordination, and more. In this Special Issue, we present some technologies to meet these demanding requirements and facilitate coordinating wireless networks to support future Beyond 5G networks.
    Keywords: 5G fiber optic networks ; data-driven service assurance ; next generation networks ; predictive analytics ; live-video delivery ; 5G networks ; virtualized content delivery networks ; network function virtualization ; service function chain deployment ; deep reinforcement learning ; MAC classification ; vehicular networks ; VANETs ; distributed MAC ; centralized MAC ; multi-channel MAC ; single-channel MAC ; spectrum allocation ; private 5G ; mmWave RAN ; modulation and coding schemes ; spectral efficiency ; self-organization ; self-optimization ; self-healing ; SON applications and architecture ; SON design and dimensioning ; machine learning (ML) and artificial intelligence (AI) for SON ; massive Machine-Type Communication (mMTC) ; IoT ; URLLC ; backhauling ; SON for 3G/4G ; 5G and B5G networks ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNB Energy industries and utilities
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Processing and Conversion of Oil and Gas: Modeling, Control, Simulation, and Optimization describes the core of the activity of petrochemical engineers, process controller engineers, industrial engineers, energy engineers, and researchers in the oil and gas field. This reprint explores the modeling, control, simulation, and optimization of new and revamped petrochemical processes using proven software. Thus, it offers novel illustrative examples, prospective applications, and solutions to improve these processes. This reprint aims to combine theoretical principles with examples modeled by commonly used simulation software employing steady-state or dynamic process simulation. Furthermore, applying numerical methods and optimization at both the theoretical and practical levels is within the scope of this reprint.
    Keywords: jet stability ; swirl ; twist ; dominant mode ; Brassica Napus ; fatty acid methyl esters ; 2-Ethyl-2-hydroxymethyl-1,3-propanediol ; viscosity ; batch reactor ; kinetics ; self-excited oscillation pulse jet ; nozzle ; large eddy simulation ; peak velocity ; cavitation number ; coal tar ; wash oil ; nitrogen-containing compounds ; indole ; formamide equilibrium extraction ; price bubbles ; bubble length ; petroleum products ; GSADF ; Pakistan ; pipeline safety ; risk classification ; pipeline failure ; fuzzy analytic hierarchy process ; pipeline risk assessment ; shale gas pipelines ; pressure gradient ; gas–liquid two-phase flow ; flow patterns ; Generalized Additive Model ; dimensionless numbers ; discrete element method ; optimal design ; simulation analysis ; anti-corrosion pill particles ; butyl acetate ; acetic acid ; n-butanol ; esterification ; membrane reactor ; reactive distillation ; amberlyst-15 catalyst ; energy efficiency ; economic evaluation ; methyl isobutyl ketone (MIBK) ; acetone self-condensation ; selective hydrogenation ; process development ; heat integration ; economic analysis ; nano-Pd/nano-ZnCr2O4 catalyst ; dimethyl carbonate ; dimethyl oxalate ; oxidative carbonylation ; azeotropic distillation ; profitability analysis ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The purpose of this Special Issue on inclusive research is to capture internationally, “How far have we come?” and “Where do we need to go?” Such questions are relevant now that it has been close to two decades since Walmsley and Johnson (2003) first introduced the inclusive research paradigm in their text, Inclusive research with people with learning disabilities: past, present, and futures. Within this Special Issue we have reprinted 18 articles that promote inclusive research as a paradigm that has succeeded in transferring power to people with intellectual disabilities who were once the "researched" to now being and becoming the "researchers". The articles draw upon the work of co-researchers both with and without the lived experience of disability who have adopted inclusive research as a paradigm to redress the exclusion of people with intellectual disabilities as researchers. All the 18 articles have an eye on the future and are sequenced across the following themes: the individual impact of being and becoming an inclusive researcher; building inclusive research relationships as a duo; being part of an inclusive research network; and using inclusive research to push boundaries and facilitate issues of importance identified by people with disabilities. The reprint concludes with two articles where inclusive researchers of long standing reflect on how to continue to walk forward on the road that aided by this reprint will become more well-travelled?
    Keywords: university ; higher education ; intellectual disability ; inclusive education ; autoethnography ; Down Syndrome ; action research ; design research ; inclusion ; social workers ; intellectual disabilities ; inclusive research ; participatory research ; developmental disability ; mental health ; collaborative groups ; qualitative research ; creative methodologies ; people with intellectual disabilities ; profound intellectual and multiple disabilities ; belonging ; intersubjectivity ; disability studies ; COVID-19 ; lived experience ; disability ; community researchers ; prisoners ; former prisoners ; criminal justice system ; inclusive employment ; collaborative autoethnography ; ethnography ; collaboration ; pandemic ; relationships ; research methods ; health ; rehabilitation ; assistive technology ; consumer-led ; employment ; students with intellectual disability ; sex education ; sexuality and gender identity ; sexual abuse ; inclusive ; research ; learning/intellectual disability ; impact ; life history ; rights ; community ; capacity building ; policy ; and practice ; funding ; co-design ; co-researching ; research with people with intellectual disability ; research with people with learning disability ; advocacy ; self-advocacy ; manifesto for inclusive research ; accessible academic literature ; space and non-accessible space ; down syndrome ; quality of life ; happiness ; n/a ; bic Book Industry Communication::J Society & social sciences::JM Psychology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: It is increasingly being recognized that land use and land cover changes driven by anthropogenic pressures are impacting terrestrial and aquatic ecosystems and their services, human society, and human livelihoods and well-being. This Special Issue contains 12 original papers covering various issues related to land use and land use changes in various parts of the world (see references), with the purpose of providing a forum to exchange ideas and progress in related areas. Research topics include land use targets, dynamic modelling and mapping using satellite images, pressures from energy production, deforestation, impacts on ecosystem services, aboveground biomass evaluation, and investigations on libraries of legends and classification systems.
    Keywords: savannah ; multifunctionality ; protected areas ; conservation ; airborne laser scanning ; aboveground woody biomass ; CORINE land cover ; mapping of changes ; GIS tools ; land cover flows ; Low Tatras National Park ; land use and land cover ; ecosystem service value ; Google Earth Engine (GEE) ; forest fragmentation ; transboundary landscape ; Himalaya ; land-cover change ; MSPA ; cluster analysis ; land use management ; synthesis of land use/land cover definitions ; meta-analysis studies in land use/land cover ; challenges and knowledge gaps in land use/land cover assessments ; literature review ; land use change ; modeling ; scenario ; deforestation ; DINAMICA EGO ; PFBC landscapes ; Democratic Republic of the Congo ; tree diversity ; ecosystem resilience ; native tree ; urban environment ; urbanization ; land cover ; land use ; change mapping ; land use pressures ; energy production ; forestry ; caatinga domain ; digital classification ; remote sensing ; land consumption ; land re-naturalization ; developed land recycling ; urban land use efficiency ; interoperability ; standards ; geospatial ; semantic ontology ; harmonization ; classification ; urban growth ; land cover change ; driving forces ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQD Environmental monitoring
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The Special Issue “Demand Response in Smart Grids” includes 11 papers on a variety of topics. The success of this Special Issue demonstrates the relevance of demand response programs and events in the operation of power and energy systems at both the distribution level and at the wide power system level. This reprint addresses the design, implementation, and operation of demand response programs, with focus on methods and techniques to achieve an optimized operation as well as on the electricity consumer.
    Keywords: demand response ; population evolution ; irrational behavior ; Markov state ; non-cooperative game ; solid electric thermal storage ; cyber–physical model ; K-means ; support vector machine ; neural network ; data analysis ; demand response (DR), load profile clustering ; k-means ; targeting of customer ; aggregator ; ramp period ; real-time simulation ; multi-objective optimization ; social welfare metrics ; energy allocation ; load disaggregation ; percentage total harmonic distortion and non-intrusive identification of load pattern ; charging strategy ; optimization ; electricity pricing ; electric vehicle ; flexibility ; flexibility market ; home energy management system ; energy flexibility ; industrial energy management ; demand side management ; control approaches ; energy management ; optimization method ; objective function ; control constraints ; Demand Response ; dynamic thermal rating ; hosting capacity ; transformer ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The diversity of wood and non-wood forest products is enormous and reflected in their anatomical, physical and chemical properties as well as their potential applications. Special attention should be given to lesser-known species and even to invasive species, which may be profitable when properly managed, thereby decreasing the overexploitation of threatened species. Besides the market importance of stem wood, other tree components and non-wood forest products, often regarded simply as forest residual materials, are valuable forest resources with various potential applications that can strengthen the circular economy. Assessing the characteristics of these diverse materials, such as their structure and anatomy as well as their physical and chemical properties, is fundamental for evaluating their potential and increasing high-quality end-uses. This knowledge will also contribute to sustainable forest management with enhanced forest diversity and species conservation in addition to the reinforcement of certification and environmental policies.
    Keywords: Calamus zollingeri ; Calamus ornatus ; dynamic vapor sorption ; basic density ; volumetric swelling ; white rot ; mold ; Quercus suber L. ; seasonal variation ; cuticular waxes ; leaves ; new species ; morphology ; wood ; properties ; chemical composition ; spectroscopy ; chemometrics ; unconventional species ; Quercus suber ; cork borer ; cork ; phenolics ; tropical species ; wood anatomy ; wood density ; wood color ; multivariate analysis ; species diversity ; dark-brown zone ; lenticular filling tissue ; quantitative anatomical characteristics ; Quercus variabilis ; reproduction cork ; scanning electron microscopy ; sclereid ; virgin cork ; Cytisus scoparius ; liquefied ; optimization ; eco-valorization ; agro-industrial residues ; Asparagaceae ; lignocellulose ; crystalline cellulose ; syringyl/guaiacyl ; anatomy ; Tilia amurensis Rupr. ; Tilia mandshurica Rupr. & Maxim. ; branch ; wood properties ; papermaking material ; tropical timber ; color parameters ; mid-infrared spectroscopy ; FTIR ratios ; environmental factors ; West African Sahel ; Cupressus funebris Endl. wood ; wood knots ; physical properties ; wood color properties ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Energy is an important material basis that can promote the development of human society. Despite the increasing use of renewable energy, the overall energy supply is dominated by fossil fuels. For a long period of time, the main consumption proportion of fossil energy will not change. With the perspective of fossil fuels such as coal, oil, natural gas, shale oil, shale gas, and combustible ice, energy exploration, reservoir reconstruction, and intelligent applications in energy exploitation and energy occurrence geology are currently explored from the perspectives of exploration and exploitation technology. This reprint summarizes the intelligent unmanned mining and its development trends and conducts various research studies, including the stratigraphic correlation of sandy conglomerate in the Yellow River Delta Sag of the Bohai Bay basin, the growth and distribution of coal-measured hydrocarbon source rocks in a mixed platform, the physical and mechanical properties of sandstone, mudstone and granite in the geological environment of deep energy reservoirs, the formation mechanism of energy reservoirs and gas reservoirs, the two-phase flow experiment and numerical simulation in energy mining, the evolution law of cracks in the surrounding rock and the reinforcement principle of gradient support, and the comparison of particle pickup by axial flow and swirling flow in horizontal pneumatic conveying.
    Keywords: intelligent mine ; smart mining ; intelligent working face ; intelligent control ; adaptive ; robotic technology ; seismic rock physics ; sandstone and mudstone ; P-wave and S-wave velocity ; pressure ; temperature ; sandy conglomerate ; Huanghekou Sag ; stratigraphic correlation ; calcite U-Pb dating ; detrital zircon ; pressure-controlled pyrolysis ; oil–water separation ; centrifugal force ; two-phase vapor separation ; cyclone separation ; Tarim Basin ; mixed platform ; delta ; coal-measure distribution ; coal-measure logging response ; axial flow ; swirling flow ; pickup behavior ; coefficient of variation ; tight sandstone gas reservoir ; nuclear magnetic resonance ; fracture ; water blocking ; n/a ; rock mechanical properties ; MMTS ; geothermal development ; geothermal reservoir ; different depth of occurrence ; gas storage ; injection production simulation ; effective permeability ; seepage law ; two-dimensional simulation experiment ; fracture evolution law ; fractured seepage zone ; gradient failure support ; hierarchical control mechanism ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: This Special Issue covers current and relevant information about the applied anatomy of domestic animals, new companion animals and wild animals. It includes recent research and review articles on diverse topics based on the use of different diagnostic imaging techniques and more classic anatomical methods, providing a deeper insight into the healthy anatomy of diverse structures, which is crucial in high-quality medicine.
    Keywords: bear pelvic limb ; dog antebrachium ; horse trunk ; horse and human comparative anatomy ; magnetic resonance imaging ; anatomy ; elbow joint ; Bengal tiger (Panthera tigris tigris) ; striped dolphin (Stenella coeruleoalba) ; fetal development ; PET/SPECT/CT ; MRI ; sectional anatomy ; head anatomy ; ontogenesis ; forensics ; analysis ; Iberian wolf ; bite marks ; veterinary ; dentistry ; CT angiography ; sections ; dissections ; thorax ; neonatal foal ; computed tomography ; development ; incisor ; radiograph ; amphibians ; anurans ; sex determination ; magnetic resonance ; ultrasonography ; feline ; lower jaw ; neurovascular supply ; temporomandibular joint ; tooth ; common dolphin (Delphinus delphis) ; pilot whale (Globocephala melas) ; nose ; nasal cavity ; endoscopy ; dissection ; 3D reconstruction ; histology ; ontogeny ; mandibular fracture ; head ; Komodo dragon ; internal vertebral venous plexus ; canine ; Striped dolphin (Stenella coeruleoalba) ; Common dolphin (Delphinus delphis) ; Pilot whale (Globicephala melas) ; Risso’s dolphin (Grampus griseus) ; Harbour porpoise (Phocoena phocoena) ; mouth ; buccal ; oral ; pharyngeal ; cavity ; horse ; phalanx ; radiogrametric study ; veterinary anatomy ; n/a
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: In this reprint, state-of-the-art research and review articles on emerging material systems for additive manufacturing (AM) are collected, with a focus on the process–structure–properties relationships. Additive manufacturing (AM) has grown and evolved rapidly in recent years. There are many exciting research and translational works in many areas of application, such as biomedical, aerospace and electronics. These advancements are typically coupled with materials development, which has resulted in more functionalities added to 3D-printed parts, such as multi-material fabrications and integration with machine learning or digital twins. Such enhancements in functionalities have enabled the evolution of AM from a rapid prototyping tool to an actual manufacturing solution. In this reprint, two reviews and thirteen original research articles are included to highlight the latest development in the field of materials science for AM.
    Keywords: titanium scaffolds ; 3D printing ; pore design ; selective laser melting ; lattice structures ; torsion ; design ; additive manufacturing ; functionally gradient lattice ; torsional stiffness ; energy absorption ; failure behavior ; ferritic steel ; heat treatment ; SLM ; nuclear application ; laser powder bed fusion ; solidification crack ; hot crack ; aluminum alloy powder ; EN AW-5083 ; AA5083 ; AlSi10Mg ; powder bed fusion ; metal matrix composites ; laser powder-bed fusion ; aluminum alloys ; reinforcement ; ceramic particulates ; grain refinement ; crystallographic texture ; mechanical properties ; laser-directed energy deposition ; melt pool ; process maps ; multi-fidelity Gaussian process ; Bayesian Optimization ; uncertainty quantification ; K418 alloy ; orientation ; phase ; microhardness ; color 3D printing ; penetration depth ; chromaticity ; image-based metric ; color reproduction ; Ti-24Nb-4Zr-8Sn ; titanium alloy ; biomedical engineering ; microstructure ; X-ray diffraction ; directed energy deposition ; shape-memory alloys ; joining of metals ; elemental powders ; 3D concrete printing (3DCP) ; hybrids ; geopolymer ; frost resistance ; UV radiation ; thermal conductivity ; surface finishing ; physical vapor deposition ; composites ; recycling ; polymer-matrix composites (PMCs) ; direct ink writing ; liquid deposition modeling ; glass fibers ; stainless steel ; AISI 316L ; AISI 630 (17-4PH) ; AISI 420 ; AISI 440C ; carbon content ; online monitoring ; electron beam melting ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Personalized medicine for Parkinson’s disease is a growing and emerging concept in light of recent recognition that Parkinson’s is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven “one size fits all” management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital “checklists” to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
    Keywords: Parkinson’s disease ; movement disorders ; periodontitis ; periodontal disease ; hematologic tests ; Vitamin D ; oral health ; Parkinson’s Disease ; cognition ; GABAergic signaling ; cerebellum ; MRS ; response inhibition ; non-motor symptoms ; carer stress ; older persons with Parkinson’s disease ; education ; lifestyle behaviours ; diet ; cross-sectional ; population study ; neurological disorders ; precision medicine ; genetics ; clinical trials ; Parkinson’s disease (PD) ; cognitive rehabilitation ; intervention ; deep brain stimulation ; levodopa-carbidopa intestinal gel ; apomorphine ; radiofrequency ; focused ultrasound ; induced pluripotent stem cells ; cell therapy ; gene therapy ; personalized medicine ; advanced Parkinson’s disease (APD) ; apomorphine subcutaneous infusion therapy ; pain ; intrajejunal ; levodopa ; motor and non-motor symptoms ; PKG (KinetiGrap) ; rehabilitation ; device-aided therapies ; personalised medicine ; Alzheimer’s disease ; clinical trial ; impulsive-compulsive disorders (ICD) ; dopaminergic therapy ; genetic markers ; pharmacogenetic ; polymorphisms ; insomnia ; sleep quality ; assessment ; young onset Parkinson’s (YOPD) ; Emiratis ; expatriate ; genetic ; epigenetics ; societal impact ; device aided therapies ; quality of life ; non motor symptoms ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Herein we describe some molecular aspects of the recent anti-COVID-19 research, including some approaches making use of natural remedies, especially from medicinal plants, in silico methods, and different experimental procedures that led to the discovery of novel targets of SARS-CoV-2 and consequently novel potential COVID-19 therapeutics. COVID-19 vaccines also find mention in this book with also a description of some adverse effects reported in some cases. Considering that the different beta coronaviruses present certain conserved biomolecular mechanisms and, thus, some common therapeutic targets, finding effective therapies for a specific member of their family (such as SARS-CoV, SARS-CoV-2, and MERS-CoV) even in a scenario of a reduced impact at the time of the related disease on humankind is still relevant as it could offer or inspire efficacious therapeutic strategies not only in the context of novel pathogenic mutations of the already known beta coronaviruses, but also when future zoonoses caused by other beta coronaviruses will emergence, which is not unlikely to occur in the current world where the interactions between humans and wildlife are made more and more frequent due to the growing loss of intact ecosystems worldwide.
    Keywords: coronavirus infections ; pandemics ; natural compounds ; clove ; Syzygium aromaticum ; eugenol ; eugeniin ; SARS-CoV-2 ; COVID-19 ; phytochemicals ; herbal medicine ; catechin ; polyphenol ; tea leaf extract ; theaflavin ; virucidal activity ; MERS-CoV ; S1-NTD ; pharmacophore modeling ; ADME ; quantum mechanical calculation ; DFT ; FMO ; MM/GBSA ; molecular docking ; Molecular Dynamics Simulation ; HOMO ; LUMO ; COVID-19 vaccine ; disseminated intravascular coagulation ; heparin induced thrombocytopenia ; platelet factor 4 ; thrombosis ; thrombotic thrombo-cytopenic purpura ; vaccine induced thrombocytopenia and thrombosis ; disinfectants ; ethanol ; hand hygiene ; ozonated water ; slightly acidic electrolyzed water ; virucidal mechanism ; coronavirus ; renal disease ; nephrotoxicity ; reno-protective effect ; green tea ; epigallocatechin-3-gallate (EGCG) ; flavonoids ; natural products ; medicinal plant ; SARS-Cov-2 nsp10 ; structural similarity ; fingerprint ; ADMET ; toxicity ; main protease ; triazole ; docking ; MD simulation ; drug ; proteomic ; vaccine ; immunology ; biomarker ; cheminformatics ; phytocompounds ; systems pharmacology ; anti-COVID-19 ; drug repositioning ; molecular dynamic simulations ; binding free energy ; signal peptide ; RBD protein ; secretion ; mutant ; nucleocapsid or nucleoprotein ; structure-based drug discovery ; alphafold model and molecular dynamics ; neuroinflammation ; brain fog ; neuropeptides ; neurotransmission ; metabolism ; NSAIDs ; inflammation ; ketoprofen ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The reprint focuses on the latest research in cybersecurity and data science. Digital transformation turns data into the new oil, so the increasing availability of big data, structured and unstructured datasets, raises new challenges in cybersecurity, efficient data processing and knowledge extraction. The field of cybersecurity and data science fuels the data-driven economy. Innovations in this field require strong foundations in mathematics, statistics, machine learning and information security. The unprecedented increase in the availability of data in many fields of science and technology (e.g., genomic data, data from industrial environments, network traffic, streaming media, sensory data of smart cities, and social network data) ask for new methods and solutions for data processing, information extraction and decision support. This stimulates the development of new methods of data analysis, including those adapted to the analysis of new data structures and the growing volume of data. The papers included in this reprint discuss various topics ranging from cyberattacks, steganography, anomaly detection, evaluation of the attacker skills, modelling of the threats, and wireless security evaluation, as well as artificial intelligence, machine learning, and deep learning. Given this diversity of topics the book represents a valuable reference for researchers in cybersecurity security and data science.
    Keywords: steganography ; network security ; steganography detection ; steganalysis ; machine learning ; big data ; IoT ; pattern mining ; wireless communications ; covert channel ; dirty constellation ; wireless postmodulation steganography ; phase drift ; drift correction modulation ; undetectability ; security ; quadrature amplitude modulation ; spam ; phishing ; classification ; augmented dataset ; multi-language emails ; cybersecurity ; data protection ; SoC ; threat agents ; motivation ; opportunity ; capability ; user profiling ; implicit ; modeling ; real-time user monitoring ; complexity threat agent ; threat assessment ; network traffic analysis ; convolutional neural networks ; network traffic images ; visualization of traffic ; classifiers ; e-mail ; ham ; data science ; datasets ; cyber threats modeling ; multi-agent systems ; cyber deception ; pseudorandom sequences generators ; prime numbers ; additive Fibonacci generator ; statistical characteristics ; android device ; BrainShield ; hybrid model ; malware detection ; Omnidroid ; image processing ; BOSS database ; ensemble classifier ; deep learning ; stegomalware ; traffic analysis ; network probe ; hash function ; SHA-3 ; FPGA ; cognitive security ; cyberattacks ; game software ; threat matrix computing ; evaluation function ; data modeling ; authentication ; bit template ; information-processing electronic device ; Poisson pulse sequences generators ; n/a ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNT Media, information & communication industries::KNTX Information technology industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In the urological sphere, the number of tumor malignancies caused by cancer is continuously growing in Western countries. Although this is mainly due to the contemporary increase in the life expectancy of people in these geographic areas, many other factors are also contributing to this growth. Urological cancer is a complex and varied disease which affects different organs and mainly affects the male population. In fact, in most statistics, kidney, prostate, and bladder cancer are regularly included in the top-ten list of the most frequent neoplasms in males. The female population, however, has also been increasingly affected by renal and bladder cancer in the last decade. From these facts, it is clear that urological cancer is a problem of major concern in developed societies. This Topic Issue of Cancers intends to shed some light on the complexity of this field and will consider all useful and appropriate contributions from scientists and clinicians in order to improve urological cancer knowledge for patients’ benefit.
    Keywords: high-risk prostate cancer ; androgen receptor axis ; castration resistance ; neuroendocrine carcinoma ; PARP inhibition ; immunotherapy ; cancer genome ; precision targeting ; robot-assisted partial nephrectomy ; renal cell carcinoma ; indocyanine green ; nephron sparing ; prostate cancer survivors ; follow-up care ; primary health care ; general practice ; process evaluation ; Consolidated Framework for Implementation Research ; prostate-specific membrane antigen positron-emission tomography ; multiparametric magnetic-resonance imaging ; primary diagnosis ; prostate cancer ; systematic review ; diagnosis ; PSMA ; PSA ; tumor ; PET scan ; bladder cancer ; bisphenol A ; bisphenol S ; energy metabolism ; migration ; proliferation ; carbon-ion radiotherapy ; elderly patients ; radiotherapy ; particle beam therapy ; life expectancy ; systemic immune-inflammation index ; Charlson comorbidity index ; CAPRA-S ; early survival ; male incontinence ; robotic prostatectomy ; clear cell renal cell carcinoma ; ferroptosis ; prognostic model ; TCGA ; E-MTAB-1980 ; GLS2 ; pazopanib ; real-world data ; non-interventional study ; time on drug ; nivolumab ; everolimus ; trial-eligibility ; ureteral neoplasms ; urinary bladder neoplasms ; ureteroscopy ; CNTF ; CNTFRα ; LNCaP ; 22Rv1 ; castration resistant ; castration sensitive ; STAT3 ; ERK ; MMP ; biomarker ; Gleason grade ; transforming growth factor-β family ; activin ; INHBA ; INHBB ; INHBC ; prostate-specific antigen ; false-positive results ; real world-data ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-06-23
    Description: Virtual and augmented reality technology has seen tremendous progress in recent years, enabling novel and exciting ways to interact inside virtual environments. An interesting approach to interaction in VR and AR is the use of tangible user interfaces, which leverage on our natural understanding of the physical world and how our bodies move and interact with it, and on our learned capabilities to manipulate physical objects.For this Special Issue, we are interested in gathering research that bridges atoms and bits in virtual and augmented environments. Basic research papers that demonstrate new interaction technologies or techniques, descriptions of applications that use tangibles in VR/AR in any domain, and survey papers that can help structure and systematize current knowledge on this area are all suitable.
    Keywords: virtual reality ; haptic feedback ; tactile sensation ; sound source localization ; deaf and hard-of-hearing ; visual positioning system ; convolutional neural network ; three-dimensional object pose estimation ; voxel ; perspective-n-point ; digital taste ; galvanic taste stimulation ; taste augmentation ; mulsemedia ; taste modulation ; augmented reality ; PCNL ; simulation ; surgical rehearsal ; surgery ; immersive environment ; cognitive impairment ; physical disability ; unity ; rehabilitation ; intention prediction ; gaze-based interaction ; laparoscopic AR navigation ; liver surgery ; 3D image registration method ; point cloud registration ; collaborative robotics ; acceptability ; uncanny valley ; user experience ; extended reality ; artificial intelligence ; classification ; control ; motor rehabilitation ; prosthesis ; stroke ; surface electromyography signals ; user interface ; pseudo-haptic ; human-centered computing ; mixed and augmented reality ; game-based learning ; fantasy ; situated learning ; serious game ; embodied interaction ; data visualization ; node-link diagram ; immersive communication ; VR conference room ; panoramic live broadcast ; spatial audio ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The intention of this Special Issue is to focus on new aspects of drug discovery, including the search for new molecular targets of various diseases, the creation of new modern methods for diagnosing diseases, the development of new test systems and kits for assessing the selectivity and effectiveness of new drugs, the study of the molecular mechanisms of biologically active compounds, the formulation of new drugs, pharmacokinetic and pharmacodynamic studies, and preclinical trials of important molecules.
    Keywords: Streptococci ; antimicrobials ; QSAR ; MD simulation ; Kunitz-type peptides ; neuroprotective activity ; sea anemones ; TRPV1 ; P2X7R ; Parkinson’s disease (PD) ; diffuse large B cell lymphoma (DLBCL) ; deep neural network ; drug discovery ; drug combination ; biomarker ; cancer severity ; cancer prognosis ; MAFB ; tumor-associated macrophages ; prostate cancer ; photodynamic therapy ; magnetic resonance imaging ; ex vivo ; anti-inflammatory substance ; N-acylhydrazone ; naphthyl-N-acylhydrazone ; LASSBio-1524 analogues ; phosphacoumarin ; azomethine ylide ; cycloaddition ; anti-cancer ; cytotoxicity ; quantum chemistry ; pravastatin ; metformin ; radiation-induced intestinal injury ; minipigs ; epithelial regeneration ; inflammation ; arylazo sulfones ; DNA binding ; DNA cleavage ; DNA photocleavage ; A375 melanoma cells ; molecular docking ; radicals ; N–S bond homolysis ; platinum(II) ; five-coordinate complexes ; glycoconjugation ; cytotoxic activity ; protein X-ray structure ; lipophilicity ; natural products ; acetylcholinesterase inhibitors ; butyrylcholinesterase inhibitors ; Alzheimer’s disease ; central nervous system ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Current practice involves the use of 3D surgical planning and patient-specific solutions in multiple surgical areas of expertise. Patient-specific solutions have been endorsed for several years in numerous publications due to their associated benefits around accuracy, safety, and predictability of surgical outcome. The basis of 3D surgical planning is the use of high-quality medical images (e.g., CT, MRI, or PET-scans). The translation from 3D digital planning toward surgical applications was developed hand in hand with a rise in 3D printing applications of multiple biocompatible materials. These technical aspects of medical care require engineers’ or technical physicians’ expertise for optimal safe and effective implementation in daily clinical routines.The aim and scope of this Special Issue is high-tech solutions in personalized surgery, based on 3D technology and, more specifically, bone-related surgery. Full-papers or highly innovative technical notes or (systematic) reviews that relate to innovative personalized surgery are invited. This can include optimization of imaging for 3D VSP, optimization of 3D VSP workflow and its translation toward the surgical procedure, or optimization of personalized implants or devices in relation to bone surgery.
    Keywords: maxillectomy ; guided surgery ; zygomatic implants ; digital ; 3D ; prosthetic rehabilitation ; head and neck oncology ; maxillary tumor ; maxillary reconstruction ; 3D VSP ; osteoradionecrosis ; mandible ; radiotherapy ; surgery ; computer assisted surgery ; virtual surgical planning ; fracture ; virtual reduction ; 3D printing ; patient-specific customized plate ; spine surgery ; virtual surgical planning (VSP) ; 3D-printing ; patient-specific instrumentation ; drill guides ; computer-assisted surgery ; image-guided surgery ; image-guided navigation ; pedicle screw ; lateral mass screw ; precision ; condylar resection ; unilateral condylar hyperplasia ; hemimandibular hyperplasia ; hemimandibular elongation ; cone-beam computed tomography ; panoramic radiography ; imaging ; 3D virtual surgical planning ; mandibular fractures ; mandibular condyle ; three-dimensional imaging ; classification ; diagnoses ; 3D-VSP ; CAD/CAM ; FEA ; finite element analysis ; masticatory ; muscle force ; jaw ; biomechanical ; intrinsic strength ; patient-specific ; custom ; bite force ; muscle delineation ; patient-specific implants ; orbital reconstruction ; surgical navigation ; additive manufacturing ; 4D ; motion analysis ; kinematic ; prosthesis ; TMJ ; TJR ; 3D technology ; three-dimensional ; corrective osteotomy ; osteotomies ; malunion ; patient-specific instruments ; surgical guide ; acetabular fracture ; 3D fracture analysis ; 3D gap area ; three dimensional ; three-dimensional measurements ; 3DCT ; personalized medicine ; dental osseointegrated implants ; prefabricated fibula free flap ; mandible and maxilla surgery ; surgical design and simulation ; virtual planning ; n/a ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBG Medical equipment & techniques
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  • 86
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-07-14
    Description: Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, “Marine Natural Products as Anticancer Agents 2.0”, gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents.
    Keywords: Clavatadine C ; spirocyclic bromotyrosines ; cytotoxicity ; cancer selectivity ; marine compounds ; melanoma A-375 cell line ; Sarcophyton convolutum ; sarcoconvolutum A–E ; cembrenoids ; anti-angiogenesis ; bromophenols ; tube formation ; vasculogenic mimicry ; brefeldin A ; ester derivative ; chronic myelogenous leukemia ; BCR-ABL ; proliferation inhibition ; molecular modeling ; 5-O-(N-Boc-l-alanine)-renieramycin T ; Xestospongia sp. ; marine sponge ; lung cancer ; anti-cancer ; cancer stem cells ; apoptosis ; Akt ; c-Myc ; migrastatics ; cell migration ; cell invasion ; metastasis ; terpenes ; algae ; marine natural products ; mitochondrial dysfunction ; oxidative stress ; anticancer ; Sphaerococcus coronopifolius ; seaweed ; Laminaria japonica ; Laminaria japonica peptides ; cancer ; liver ; cell cycle ; porphyrin ; Isabela ; hemin ; X-ray diffraction ; NOESY NMR ; cytotoxic ; colorectal cancer ; 5-fluorouracil ; 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid ; tumor-associated macrophages ; chemoresistance ; fucoidan ; immunopotentiation ; immunomodulatory ; immunotherapy ; cancer treatment ; cytokines ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint focuses on the position of sustainability in engineering and points to the multidimensionality of the issue. Architecture, civil and engineering issues are main themes of discussion, with special attention to research and design. Attention is focused on four thematic groups: energy (including energy harvesting), economy (including building circularity), pro-health activities, and design.
    Keywords: CFD ; mechanical ventilation ; industrial buildings ; thermal comfort ; air quality ; natural environment ; construction sector ; steel ; sustainable development ; cradle-to-gate with options ; Life Cycle Assessment ; life cycle costs ; maintenance costs ; warranty period ; number of use cycles ; building circularity assessment ; material flow model ; building circularity material passport ; building circularity calculation method ; adaption ; landscape pattern ; local microclimate ; comprehensive analysis ; morphological parameters ; space syntax ; façade configuration ; visual perception ; built heritage ; Kaunas ; cultural sustainability ; PV system ; social acceptability ; system dynamics ; CO2 emissions ; feed-in-tariffs ; subsidy policy ; water management ; housing environment quality ; multi-family settlements ; Bio-Morpheme ; greenery ; automated design ; plant selector ; sustainability ; algorithmic design ; landscape design ; BIM ; green BIM ; city breathability ; urban ventilation ; urban air quality management ; blue-green infrastructure ; integrated urban planning ; economic analysis ; marketplace regeneration ; optimisation ; spatial analysis ; urban design ; vibration ; energy harvesting ; green gardens ; multifunctionality ; plus-energy building ; thermal stack ; solar energy ; integrated design ; prefabricated rural housing ; PEST ; entropy weighted TOPSIS ; implementation potential ; Chongqing ; n/a ; urban planning ; building layout ; energy demand ; climate ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The Special Issue aimed to bring together scientists working in various branches of control theory to discuss manufacturing control problems that include the following: enterprise control and digital ecosystem creation; the development of identification theory and methodology, and related mathematical problems; parameter, nonparametric, and structure identification and expert analysis; problems regarding selection and data analysis; control systems with an identifier; modeling in intelligent systems; simulation procedures and software; digital identification; reinforcement learning; quantum modeling; intelligent model predictive control; predictive cognitive issues; problems with software quality for complex systems; and global network resources for support processes of modeling and control.
    Keywords: decision-making ; psychic and behavioral components of activity ; action ; result of activity ; equilibrium stability ; consensus ; threshold behavior ; cognitive dissonance ; conformity ; informational control ; informational confrontation ; soft sensing ; multivariate filter ; reactive distillation ; optimal stochastic control ; path planning ; 2D random search ; interception ; external disturbances ; invariance ; block control principle ; decomposition ; high-gain factors ; sliding mode control ; sigmoid function ; Gramian method ; bilinear system process identification ; generalized Lyapunov equation ; knowledgebase ; associative search models ; wavelet analysis ; adaptive differential evolution ; evolutionary computing ; Hammerstein ; nonlinear system identification ; bilinear systems ; eigenmode decomposition ; spectral expansions ; Gramians ; observability ; controllability ; small-signal analysis ; numerical algorithm ; tokamak ; plasma equilibrium reconstruction ; linear plasma models ; identification ; state observer ; LMI ; least square technique ; deep neural network ; parametric uncertainty ; robust control ; super-stability ; regular form ; dynamic mode decomposition ; system identification ; Runge–Kutta method ; nonparametric model ; artificial neural network ; Izhikevich artificial neuron ; vestibular–ocular reflex ; control Lyapunov function ; Bayes criterion ; Haar wavelets ; loss function ; mean risk ; observable stochastic systems (OStS) ; stochastic process (StP) ; wavelet canonical expansion (WLCE) ; nonparametric identification ; dynamic system ; integral model ; Volterra equations ; smoothing cubic splines ; selection of the smoothing option ; modeling ; regularization ; inverse problems ; balanced identification ; error analysis ; one-dimensional heat equation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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  • 89
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint focuses on research concerning various types of nanoparticles in terms of their toxicity, removal of antibiotics, and behavior in natural environments. In addition, reviews on microplastics in the atmosphere and the possible health impacts of microplastics/nanoplastics on humans are included
    Keywords: nanomaterials ; cerium oxide nanoparticles ; wild herbs ; seed germination ; root length ; nanoplastics ; nanotoxicity ; toxicology ; plastics ; health impacts ; environmental impacts ; pollution ; artificial black carbon (aBC) ; thermal treatment ; cytotoxicity ; reactive oxygen species (ROS) ; graphene oxide ; sulfamethazine ; phototransformation ; free radicals ; nanopollution ; nano-enabled products ; engineered nanomaterials ; physicochemical properties ; aquatic environments ; microplastics ; atmosphere ; distribution ; characteristics ; toxicity ; quantitative analysis ; flow-through dissolution testing ; OECD guidelines ; environmental risk assessment ; silver nanoparticles ; zinc oxide nanoparticles ; developmental toxicity ; reactive oxidative stress ; apoptosis ; autophagy ; magnetite-halloysite composites ; magnetic sorbent materials ; fluoroquinolone antibiotic ; adsorption ; wastewater treatment ; magnetic remediation ; emerging contaminants ; ecotoxicity ; ZnO nanoparticles ; trophic transfer ; neurotoxicity ; GABAergic motor neuron ; neuron damage ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Modern materials and structures are significantly different from conventional ones. Their sizes can be orders of magnitude smaller, and their compositions are so sophisticated that traditional characteristic methods are inapplicable. Non-conventional methods are essential to tackle these issues, which must often be approached in an interdisciplinary fashion. This Special Issue is a collection of articles that shed light on these problems.
    Keywords: analytical solution ; Fourier cosine series ; vibrations ; FGM rectangular plates ; Mindlin plate theory ; phased array transducer ; transducer optimization ; beam focusing ; pulse–echo mode ; harmonic generation ; stress-free boundary ; total correction ; acoustic emission ; electrical resistance ; damage monitoring ; criticality ; natural time analysis ; nonlinear parameter ; noncontact reception ; air-coupled receiver ; aluminum samples ; corrections ; field theory ; deformation and fracture ; 7075 aluminum alloy ; electronic speckle pattern interferometry ; concrete beam ; bending ; cementitious matrix ; FRCM ; analytical model ; numerical model ; linear low-density polyethylene ; digital image correlation ; optical non-destructive testing ; speckle ; fourier scaling theorem ; gaussian filtering ; optical methods ; AlSi10Mg ; SLM ; NDE ; deep learning ; CNN ; k-fold cross validation ; non-destructive testing ; optical interferometry ; residual stress ; thermal expansion ; elasticity ; high entropy alloys ; complex concentrated alloys ; refractory metal intermetallic composites ; high entropy phases ; complex concentrated phases ; Nb silicide-based alloys ; alloy design ; biomechanics ; Achilles tendon ; beam-to-beam contact ; arbitrary cross-section ; ANCF ; lithium-ion batteries ; redox-active organic anode ; organic anode materials ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PH Physics
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: A collection of 18 scientific papers written in honor of Professor Karlheinz Schwarz's 80th birthday. The main topics include spectroscopy, excited states, DFT developments, results analysis, solid states, and surfaces.
    Keywords: density functional theory ; Coulomb systems ; excited states ; nodal variational principle ; DFT ; anatase TiO2(101) surface ; adsorption energy ; Bader charge ; helium atom ; screened Coulomb potential ; variational Monte Carlo method ; Lagrange mesh method ; comparison theorem ; TD-DFT ; MC-PDFT ; Lie–Clementi ; Colle–Salvetti ; OLEDs ; subphthalocyanines ; UV–visible spectra ; axial substituents ; peripheral substituents ; time-dependent DFT ; hexatetra-carbon ; electrical properties ; molecular aggregates ; singlet excitons ; triplet excitons ; TDDFT ; charge-transfer states ; charge-resonance states ; Frenkel states ; localized excitations ; diabatic states ; adiabatic states ; semiconductors ; oscillator strength ; hybrid exchange-correlation functional ; non-local potential ; statistics ; methods comparison ; benchmarking ; band gaps ; atomization energy ; DFT codes ; electronic structure calculation ; numerical accuracy and precision ; kinetic functional ; Yukawa potential ; periodic DFTB ; deMonNano ; graphene ; graphite ; benzene dimers ; deposited benzene ; supported clusters ; weighted mulliken charges ; LAPW method ; APW+lo method ; all-electron DFT ; density matrix functional embedding ; density-functional theory ; householder transformation ; He atomic basis sets ; helium dimer ; He2 potential well ; correlation energy ; complete basis set ; sigma basis set ; atomic multiplet theory ; crystal/ligand-field theory ; coordination compounds ; electronic structure ; Cu2OCl2 ; Cu2OBr2 ; Cu2OI2 ; oxyhalides ; magnetic couplings ; Néel temperature ; chemical pressure ; NMR ; machine learning ; zeolites ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNR Physical chemistry
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  • 92
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-30
    Description: Complex systems have long been an integral part of modern life and can be encountered everywhere. Undertaking a comprehensive study of such systems is a challenging problem, one which is impossible to solve without the use of contemporary mathematical modeling techniques. Mathematical models form the basis for the optimal design and control of complex systems. The present reprint contains all the articles accepted and published in the Special Issue of Mathematics entitled "Control, Optimization, and Mathematical Modeling of Complex Systems". This Special Issue is focused on recent theoretical and computational studies of complex systems modeling, control, and optimization. The topics addressed in this Special Issue cover a wide range of areas, including numerical simulation in physical, social, and life sciences; the modeling and analysis of complex systems based on mathematical methods and AI/ML approaches; control problems in robotics; design optimization of complex systems, modeling in economics and social sciences; stochastic models in physics and engineering; mathematical models in material science; and high-performance computing for mathematical modeling. It is our hope that the scientific results presented in this reprint will serve as valuable sources of documentation and inspiration to those seeking to delve into complex systems modeling, control, and optimization and examine their wide-ranging applications.
    Keywords: optimal control problem ; evolutionary computation ; robotics applications ; optimal control ; Lyapunov stability ; equilibrium point ; symbolic regression ; Pontryagin’s maximum principle ; continuous-time Markov chains ; ergodicity bounds ; discrete state space ; rate of convergence ; logarithmic norm ; interval analysis ; function approximation ; global optimization ; convexity evaluation ; overestimators ; underestimators ; machine learning control ; general synthesis problem ; evolutionary algorithm ; adaptive interpolation algorithm ; interval ordinary differential equations (ODEs) ; sparse grids ; hierarchical basis ; multidimensional interpolation ; high dimensions ; molecular dynamics modeling ; randomized maximum entropy estimation ; probability density functions ; Lagrange multipliers ; Lyapunov-type problems ; implicit function ; rotation of vector field ; asymptotic efficiency ; thermokarst lakes ; forecasting ; dynamical tracking target ; ship towing system ; relative curvature ; adaptive control ; discrete velocity method ; lattice Boltzmann method ; computational fluid dynamics ; mathematical modeling ; estimation ; minimax techniques ; pareto optimization ; regression analysis ; statistical uncertainty ; proton exchange membrane ; proton electrolyte membrane ; PEM ; fuel cell ; PEMFC ; power electronic converter ; DC–DC boost converter ; model predictive control ; MPC ; self-scalable robots ; modular robots ; origami structures ; complex system ; synergistic effect ; performance indicator ; structure change ; soft robotics ; continuum mechanisms ; modeling of complex systems ; kinematic model of soft robots ; mathematical modeling of complex systems ; non-linear models ; soft robotic neck ; tendon-driven actuators ; mathematical modelling ; modelling in economics ; impact of the COVID-19 ; logistics businesses ; fractional-order virus models ; stuxnet virus ; numerical computing ; supervisory control and data acquisition systems ; computer networks ; lyapunov analysis ; image segmentation ; remote sensing ; terrain identification ; data synthesis ; transfer learning ; controllability ; observability ; stochastic linear systems in finite and infinite dimensional spaces ; stochastic singular linear systems in finite and infinite dimensional spaces ; semigroup ; evolution operator ; GE-semigroup ; GE-evolution operator ; stochastic GE-evolution operator ; feature selection ; finite normal mixtures ; moving separation of mixtures ; deep LSTM ; neural network architectures ; deep learning ; turbulent plasma ; air–sea fluxes ; n/a ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNT Media, entertainment, information and communication industries::KNTX Information technology industries ; thema EDItEUR::U Computing and Information Technology::UY Computer science
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  • 93
    Publication Date: 2023-04-05
    Description: This reprint includes papers from different research fields, reflecting the sectional talks presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, which took place in June 2021. The objective of the 2021 Conference was to bring together perspectives and challenges in doctoral research in a common forum and to provide a platform enabling doctoral researchers to meet and share state-of-the-art developments in their fields. It consists of 16 papers presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, in several fields such as: mechanical and industrial engineering, food science and biotechnology, electrical/electronic engineering, systems engineering and information technologies, chemistry, electrochemistry, and economic models and strategies.
    Keywords: incremental pumps ; profiling of generating tools ; helical surfaces ; Romania ; coastal area ; wind energy ; measurements ; IEC classes ; wind turbines ; mass tourism ; management model ; Constanta ; PESTEL ; Black Sea ; sustainability ; eggplant peels ; bioactive compounds ; hydrogels ; anthocyanins ; beetroot peel ; betalains ; polyphenols ; CCD-RSM ; optimal control ; metaheuristic algorithms ; evolutionary algorithms ; simulation ; ventilation on ships ; HVAC requirements ; COVID-19 ; spread the disease ; airborne transmission ; HEPA filtration ; UV disinfection ; heat recovery ; L-tryptophan ; polypyrrole ; sensor ; amino acid ; cyclic voltammetry ; chronoamperometry ; atorvastatin ; carbon nanotubes ; gold nanoparticles ; Hippophae rhamnoides L. ; carotenoids ; flavonoids ; antioxidant activity ; microencapsulation ; modulation ; electromagnetic disturbances ; electromagnetic compatibility ; military ship ; communication systems ; navigation conditions ; Danube River ; management tool ; quality function deployment ; house of quality ; enwrapping surfaces ; profiling ; geometrical methods ; tower ; wind turbine ; load ; offshore wind ; marine renewable energy ; living labs ; design thinking ; coastal zone ; integrated coastal zone management (ICZM) ; Romanian coastal zone ; Black Sea basin ; wind parameters ; historical data ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: This reprint emphasizes the perspectives and challenges surrounding COVID-19 and obesity-related cancers, including but not limited to the risk factors of severe COVID-19 in cancer patients; the complications of COVID-19 in cancer patients; the challenges in cancer treatment and surgery; guidelines for cancer care during COVID-19; delayed diagnosis and suboptimal cancer management; the impact of COVID-19 on cancer screening, early diagnosis and cancer presentation; immune response after SARS-CoV-2 infection and vaccination in cancer patients; psychological distress among cancer survivors; telehealth in cancer care; the role of diet and nutraceuticals in the prevention of severe COVID-19 and cancer; and the effects of COVID-19 pandemic on cancer research.
    Keywords: COVID-19 ; neutropenia ; G-CSF treatment ; respiratory failure ; colorectal neoplasms ; gastrointestinal neoplasms ; immune checkpoint inhibitors ; neoplasms ; oncogenic viruses ; oncolytic virotherapy ; post-acute COVID-19 syndrome ; reactive oxygen species ; tumor escape ; SARS-CoV-2 ; thyroid cancer ; differentiated thyroid cancer ; COVID-19 severity ; inflammation ; immunity ; oxidative stress ; obesity ; SARS-Cov-2 ; oncology ; cancer screening ; clinical trials ; melanoma ; management ; pandemic ; teledermatology ; diagnostic delay ; immunotherapy ; vaccination ; lymph adenopathy ; cancer ; nutraceuticals ; supplements ; colorectal ; meta-analysis ; gynecologic oncology ; malignancy ; blood cancer ; hematologic malignancy ; leukemia ; lymphoma ; multiple myeloma ; myelodysplasia ; breast cancer ; cancer care ; screening ; surgery ; psychological distress ; cancer therapies ; immunogenicity ; safety ; vaccine hesitancy ; tumor subtype ; mortality ; intensive care unit ; medico-administrative data ; France ; n/a ; bic Book Industry Communication::M Medicine
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Due to the intensive development of the global economy, many problems are constantly emerging connected to the safety of ships’ motion in the context of increasing marine traffic. These problems seem to be especially significant for the further development of marine transportation services, with the need to considerably increase their efficiency and reliability. One of the most commonly used approaches to ensuring safety and efficiency is the wide implementation of various automated systems for guidance and control, including such popular systems as marine autopilots, dynamic positioning systems, speed control systems, automatic routing installations, etc. This Special Issue focuses on various problems related to the analysis, design, modelling, and operation of the aforementioned systems. It covers such actual problems as tracking control, path following control, ship weather routing, course keeping control, control of autonomous underwater vehicles, ship collision avoidance. These problems are investigated using methods such as neural networks, sliding mode control, genetic algorithms, L2-gain approach, optimal damping concept, fuzzy logic and others. This Special Issue is intended to present and discuss significant contemporary problems in the areas of automatic control and the routing of marine vessels.
    Keywords: collision avoidance ; ship domain ; fuzzy inference ; collision risk ; early warning system ; marine vessel ; tracking controller ; stability ; functional ; optimal damping ; fin stabilizer ; ship turning ; heel/roll reduction ; L2-gain ; uncertainty ; non-linearity ; ship motion control ; path-following ; guidance algorithm ; nonlinear feedback ; AIS Data ; trajectory prediction ; waterway transportation ; neural networks ; autonomous navigation ; multi-joint autonomous underwater vehicle (MJ-AUV) ; 3-dimensional modeling ; LQR ; LESO ; multicriteria route planning ; genetic algorithm ; particle swarm optimization ; oceanic meteorological routing ; cooperative game theory ; supply chain management ; supply disruption ; unmanned surface vehicle ; Guidance, Navigation and Control ; course keeping ; adaptive sliding mode ; unmanned surface vehicle (USV) ; system identification ; traditional neural network ; physics-informed neural network ; zigzag test ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.
    Keywords: activation phenotypes ; microglia ; neuroinflammation ; immunohistochemistry ; temporal cortex ; Alzheimer’s disease ; amyloid ; amyloid β-protein (Aβ) ; mAb158 ; oligomers ; protofibrils ; amyloid aggregation ; supported lipid bilayers ; time-lapse AFM ; molecular dynamics simulation ; alzheimer’s disease ; amyloid β ; bryostatin-1 ; ECE1 ; iPS ; nELAV ; neurotoxicity ; oligomer ; protein kinase C ; α-secretase ; APP mutation ; recessive inheritance ; familial Alzheimer’s disease ; Aβ oligomers ; amyloid imaging ; microbiota ; bacterial amyloid ; FUBA ; curli ; CsgA ; amyloid beta ; oxidative stress ; supplement ; phosphodiesterase III inhibitor ; cerebral micro-hemorrhage(s) ; cerebral amyloid angiopathy ; amyloid-β protein ; transgenic mice ; NMR ; CD ; Aβ ; β-amyloid peptide ; α/β-discordant ; Dutch-type mutation ; E22Q ; FAD ; Amyloid β ; Polyphenol ; Pro-oxidant ; Alzheimer’s Disease ; molecular imaging ; amyloid β-peptides ; islet amyloid polypeptide ; high-speed atomic force microscopy ; amyloid PET ; tau PET ; amyloid precursor protein ; mutation ; cerebellum ; PBB3 ; PiB ; axon ; traditional medicines ; Polygalae Radix ; diosgenin ; naringenin ; kihito ; amyloid-β ; antimicrobial ; antiviral ; antimicrobial peptide ; neurodegenerative disease ; misfolding ; fluorescence microscopy ; FRET ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 97
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-11-30
    Description: Copper-based catalysts possess important applications in diverse reactions and have received considerable attention from material and catalysis researchers. A great challenge in this field is the facile synthesis of copper-based catalysts with enhanced catalytic activity, selectivity, and durability. This Special Issue of Catalysts, entitled “Synthesis and Applications of Copper-based Catalysts”, presents state-of-the-art synthetic strategies for copper-based catalysts, as well as information on their structure and catalytic use in heterogeneous and homogeneous catalysis, which is helpful for developing novel high-efficiency Cu-based catalysts and synthetic methodology, and for exploring their new catalytic applications.
    Keywords: metal-organic frameworks ; Cu2O ; styrene oxidation ; H2O2 ; base free ; low-temperature ; CO-SCR ; Cu-Mn oxide spinels ; Cu/Cu3P nanoarrays ; Cu nano-substrates ; electrocatalyst ; HER ; ceria ; hydride ; CO2 hydrogenation ; single Cu doping ; density functional theory ; Cu-based catalysts ; CO + NO ; catalytic performances ; O2 resistance ; H2O and SO2 resistance ; adsorption ; dissociation ; density-functional theory calculations ; Cu-skin Cu3Au(111) surface ; CO catalytic oxidation ; CO preferential oxidation ; template ; CTAB ; mixed oxides ; copper oxides ; tin oxides ; BCN/graphene composite ; CVD ; anti-corrosion ; organocopper reagents ; Cu catalysts ; 1,4-conjugate addition ; sulfur heterocycles ; thiochromone ; thioflavanones ; 2-alkylthiochroman-4-ones ; copper ; catalysis ; amination ; amines ; polyamines ; aryl halides ; adamantane ; nanoparticles ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This Book, entiled “Allergic Rhinosinusitis and Airway Diseases”, presents the concept of united airway disease interaction, which comprises chronic rhinosinusitis and other lower airway disorders such as asthma. This concept furthers a deeper comprehension on the pathophysiology and management of upper and lower airway diseases. In this Book, the published papers cover different interesting topics such as healthcare equality, advanced biomarkers, accurate diagnosis and treatment, occupational exposure-induced upper airway allergy and neoplastic disease mimicking chronic rhinosinusitis.
    Keywords: chronic rhinosinusitis ; B-cell lymphoproliferative disorder ; sinus ; nasal allergies ; tannery worker ; Kanpur ; asthma ; ovalbumin ; saffron ; salbutamol ; IL’s ; TNF-α ; allergic rhinitis ; bronchial asthma ; allergy ; Th17 cells ; IL-17 ; IL-33 ; microRNA ; miR ; airway mucosal inflammation ; united airway disease ; acute rhinosinusitis ; acute recurrent rhinosinusitis ; Mediterranean diet ; nutritional evaluation ; nutritional therapy ; olfactory dysfunction ; anosmia ; post-acute COVID-19 ; nitric oxide ; NO ; exhaled NO ; FENO ; nasal peak flow ; atopic status ; total IgE ; specific IgE ; childhood asthma ; immunoblot ; ImmunoCAP ; otolaryngology ; sinusitis ; ethnic groups ; patient-reported outcome measures ; quality of life ; social justice ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 99
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This reprint turns out to be very important for the pathologies deriving from the gut microbiome and its disorders. Human health seems to be correlated with the status of our microbiome, which plays a vital role in our health. The human microbiome is associated with a wide range of diseases, from non-neoplastic to tumorigenesis, including cancer, inflammation, intestinal damage, etc. Following these statements, it is possible to deduce the paramount importance of the role of the gut microbiome and the relative consequences for human well-being.
    Keywords: microbiome ; pain ; IBS ; neuropathy ; gut microbiota ; Clostridium difficile infection ; SARS-CoV-2 ; inflammation ; intestinal microbiota ; immune protection ; mast cells ; platelets ; aging ; liver cancer ; metabolomics ; metabolites ; scientific technology ; antibiotic resistance ; virulence ; metagenomics ; human gut ; antibiotic consumption ; colon cancer ; right-sided colon cancer ; left-sided colon cancer ; tumor microbiome ; gut microbiome ; nasopharyngeal microbiome ; age differences ; sex differences ; human microbiome ; 16S rRNA sequencing ; Huntington’s disease ; neurodegeneration ; gastrointestinal microbiome ; gut-brain axis ; dysbiosis ; immune ; bacteria ; proteome ; pregnancy ; FGR ; placenta ; cancer treatment ; cardiotoxicity ; Helicobacter pylori ; methods for determining H. pylori resistance ; molecular genetic diagnostics ; phenotypic methods for determining antibiotic resistance ; geographical distribution of H. pylori antibiotic resistance ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
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  • 100
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Ionizing radiation (IR) exposure can be deleterious for living tissues and eventually lead to illness or even death. DNA breakdown and the overproduction of highly reactive free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are considered initiators of IR-induced molecular and cellular damages, whereas NO, TGF-β and other pro-inflammatory cytokines are the primary effectors involved in radiation bystander effects (RIBE). Radiomodulators can reduce (radioprotectors and radiomitigators) or increase (radiosensitizers) IR damage. Past world events have highlighted the urgent need to develop predictive biomarkers of the IR absorbed dose and radiation countermeasures to reduce IR damage. Despite the strong economic and scientific efforts over the last decades, at present, drugs for effective protection against lethal IRs remain an unmet need. Moreover, the development of radiosensitizers that selectively increase IR damage in cancer cells but protecting, or at least do not affect, healthy tissues is also of unquestionable importance to improving patient survival and quality of life. It includes contributions that will help to understand the mechanisms involved in radiation-derived cellular responses and damage, the importance of free radical scavengers and antioxidant cellular defenses in preventing harm, and the relevance of the antiinflammatory response to improve recovery. In accordance, the mechanism of action and effectiveness of relevant radiomodulators are described and discussed, and novel clinical models and IR biomarker technologies are presented.
    Keywords: ferulic acid ; total body irradiation ; bone marrow microenvironment ; stem cell senescence ; bone marrow injury ; reactive oxygen species ; antioxidant defense system ; planarians ; model animal ; irradiation ; regeneration ; radioprotection ; radiation ; melatonin ; nDNA-repair ; mtDNA-mutations ; oxidation stress ; protection ; mitigation ; H2O2 ; ATP ; MDA ; GSH ; X-ray radiation ; 3T3 fibroblasts ; proliferation ; apoptosis ; cellular stress ; senescence ; peroxiredoxin 6 ; Prdx6 ; radioprotector ; pharmacologic ascorbate ; vitamin C ; pancreatic cancer ; Auranofin ; thioredoxin ; thioredoxin reductase ; peroxiredoxin ; nuclear and radiological emergencies ; radioprotectors ; radiomitigators ; radionuclide scavengers ; radiation biodosimetry ; Olea europaea L. cv. Caiazzana ; oleacein ; ionising radiation ; cancer ; radiotherapy ; normal tissue ; radiosensitization ; radiomodulation ; proteomic analysis ; oxidative modification profiling ; serum albumin ; amino acid sequences ; radiation biomarker ; human lactoferrin ; acute gamma irradiation ; C57Bl/6 mice ; survival rate ; open field test ; spleen ; serum homeostasis ; leukocytes ; stilbenoid ; electron paramagnetic resonance (EPR) ; FT-IR ; electron beam radiation ; radioresistance ; oxidative phosphorylation ; oncometabolites ; radiation response ; bioinformatics ; oxidative stress ; transcriptomics ; radiobiology database ; gene signature ; ionizing radiation ; intestine ; mucositis ; microbiome ; microbiota ; dysbiosis ; bacterial dietary supplement ; radiomitigator ; hyperthermia ; combination therapy ; synergistic effect ; oxygenation ; hypoxia ; immune response ; Tameron ; antioxidant ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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