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  • United States  (110)
  • Mutation
  • American Association for the Advancement of Science (AAAS)  (131)
  • Elsevier
  • American Institute of Physics (AIP)
  • 1975-1979  (131)
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (131)
  • Elsevier
  • American Institute of Physics (AIP)
  • Springer  (5)
Years
Year
  • 1
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    New strength in the diet-disease link? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Nov 9;206(4419):666-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493971" target="_blank"〉PubMed〈/a〉
    Keywords: Diet/*adverse effects ; Disease/*etiology ; Humans ; Legislation as Topic ; National Institutes of Health (U.S.) ; Nutritional Physiological Phenomena ; Peer Review ; Preventive Medicine/methods ; Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    NIH deals gingerly with diet-disease link (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1175-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451563" target="_blank"〉PubMed〈/a〉
    Keywords: Diabetes Mellitus/etiology ; Diet/*adverse effects ; Disease/*etiology ; *National Institutes of Health (U.S.) ; Neoplasms/etiology ; *Nutritional Physiological Phenomena ; Preventive Medicine ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Approval sought for nerve gas pilot plant (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Dec 7;206(4423):1164, 1166.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504999" target="_blank"〉PubMed〈/a〉
    Keywords: *Chemical Warfare Agents ; Containment of Biohazards ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Dispute over cancer risk quantification (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Mar 30;203(4387):1324-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/106470" target="_blank"〉PubMed〈/a〉
    Keywords: Benzene/*toxicity ; *Carcinogens ; Cost-Benefit Analysis ; Environmental Exposure ; Government Agencies ; Legislation, Drug ; Risk ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Headache for Bristol-Myers (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):540-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493959" target="_blank"〉PubMed〈/a〉
    Keywords: Advertising as Topic/standards ; Analgesics/*standards ; Aspirin/*standards ; Drug Industry/*standards ; Jurisprudence ; Nonprescription Drugs/*standards ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Basic research in the United States (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Handler, P -- New York, N.Y. -- Science. 1979 May 4;204(4392):474-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432651" target="_blank"〉PubMed〈/a〉
    Keywords: Astronomy/history ; Biology/history ; Chemistry/history ; Environment ; Government Agencies/history ; History, 20th Century ; Physics/history ; *Research Support as Topic ; Science/*history ; Social Sciences/history ; United States ; Universities/history/manpower
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Environmental health research (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hiatt, H H -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1361.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505011" target="_blank"〉PubMed〈/a〉
    Keywords: *Environmental Health ; Research ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide adenosine and deoxyadenosine adducts: structure and stereochemistry (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: The structure and absolute stereoconfigurations of four adenosine adducts with (+/-)-7 alpha,8 beta-dihydroxy-9 beta, 10 beta-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene (BPDE) and their deoxyadenosine analogs have been determined. They result from both cis and trans addition of the N6 amino group of ademine to the 10 position of both enantiomers of BDPE. This was determined from studies of the nuclear magnetic resonance spectra, mass spectra, and circular dichroism spectra, as well as from their pKa values and chemical reactivities.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jeffrey, A M -- Grzeskowiak, K -- Weinstein, I B -- Nakanishi, K -- Roller, P -- Harvey, R G -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1309-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/316186" target="_blank"〉PubMed〈/a〉
    Keywords: *Benzopyrenes ; Chemical Phenomena ; Chemistry ; Circular Dichroism ; Dna ; *Deoxyadenosines/analogs & derivatives ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Molecular Conformation ; Mutation ; Stereoisomerism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Genetic mechanism accounting for precise immunoglobulin domain deletion in a variant of MPC 11 myeloma cells (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: A variant of the MPC 11 cell line, M 311, produces a short immunoglobulin heavy chain. When compared with the parental gamma 2b heavy chain, M 311 was found to have a carboxyl terminal deletion comprising the CH3 domain. The COOH-terminal cyanogen bromide (CNBr) cleavage fragment of M 311 is identical to a corresponding segment ofa parental heavy chain CNBr fragment, with the exception of a substitution of asparagine for lysine at the COOH-terminal residue. This observation enabled prediction of both the parental DNA sequence in this region and the genetic mechanism which generated the variant, a frameshift followed by premature termination. This hypothesis is supported by studies of the DNA sequence of the MPC 11 gamma 2b constant region gene.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kenter, A L -- Birshtein, B K -- R21 AI106328/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1307-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/117550" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Chromosome Deletion ; Genes ; Immunoglobulin G/*genetics ; Immunoglobulin gamma-Chains/genetics ; Macromolecular Substances ; Melphalan/pharmacology ; Mice ; Mutation ; Myeloma Proteins/*genetics ; Neoplasms, Experimental/genetics ; Peptide Chain Termination, Translational ; Plasmacytoma/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Laboratory animal feed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knapka, J J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1367.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/582217" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed/*analysis ; Animals ; Animals, Laboratory ; Hot Temperature ; National Institutes of Health (U.S.) ; Nitrosamines/analysis ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 11
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    Large drug firms fight generic substitution (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1054-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493991" target="_blank"〉PubMed〈/a〉
    Keywords: Costs and Cost Analysis ; Drug Industry/*economics ; Legislation, Drug ; *Therapeutic Equivalency ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 12
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    The phenformin ban: is the drug an imminent hazard? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1094-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424735" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Lactates/blood ; Legislation, Drug ; Phenformin/adverse effects/*standards ; United States ; United States Dept. of Health and Human Services ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 13
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    New drugs and the brain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):774-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/379998" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; France ; History, 20th Century ; Humans ; Mice ; Psychotropic Drugs/*history/metabolism/therapeutic use ; Rats ; Schizophrenia/drug therapy ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 14
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    Controversy over study of diabetes drugs continues for nearly a decade (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):986-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/370980" target="_blank"〉PubMed〈/a〉
    Keywords: Cardiovascular Diseases/chemically induced ; Clinical Trials as Topic ; Diabetes Mellitus/*drug therapy ; Drug Information Services ; History, 20th Century ; Humans ; Hypoglycemic Agents/adverse effects/history/*standards ; Jurisprudence ; Legislation, Drug/*history ; Phenformin/adverse effects ; Research Design/standards ; Tolbutamide/adverse effects ; United States ; United States Food and Drug Administration/history
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 15
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    Panel urges wide use of antiviral drug (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1058-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/386515" target="_blank"〉PubMed〈/a〉
    Keywords: Amantadine/history/*therapeutic use ; History, 20th Century ; Humans ; Influenza A virus ; Influenza, Human/prevention & control/*therapy ; National Institutes of Health (U.S.) ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 16
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    NAS study on radiation takes the middle road (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1979 May 18;204(4394):711, 713-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441736" target="_blank"〉PubMed〈/a〉
    Keywords: Congenital Abnormalities/etiology ; Dose-Response Relationship, Radiation ; Humans ; Maximum Allowable Concentration ; Neoplasms, Radiation-Induced/etiology ; Radiation Injuries/*etiology ; Risk ; Societies, Scientific ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 17
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    Dynamics of skeletal pattern formation in developing chick limb (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-17
    Description: During development of the embryonic chick limb the skeletal pattern is laid out as cartilaginous primordia, which emerge in a proximodistal sequence over a period of 4 days. The differentiation of cartilage is preceded by changes in cellular contacts at specific locations in the precartilage mesenchyme. Under realistic assumptions, the biosynthesis and diffusion through the extracellular matrix of a cell surface protein, such as fibronectin, will lead to spatial patterns of this molecule that could be the basis of the emergent primordia. As cellular differentiation proceeds, the size of the mesenchymal diffusion chamber is reduced in descrete steps, leading to sequential reorganizations of the morphogen pattern. The successive patterns correspond to observed rows of skeletal elements, whose emergence, in theory and in practice, depends on the maintenance of a unique boundary condition at the limb bud apex.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Newman, S A -- Frisch, H L -- New York, N.Y. -- Science. 1979 Aug 17;205(4407):662-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462174" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bone and Bones/*embryology ; Cell Differentiation ; Chick Embryo ; Diffusion ; Extremities/*embryology ; Growth Substances/physiology ; Mesoderm/cytology ; Models, Biological ; Muscles/embryology ; Mutation ; Wings, Animal/*embryology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 18
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    Osmotic shock prevents nuclear exchange and produces whole-genome homozygotes in conjugating Tetrahymena (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: Exposure of conjugating Tetrahymena to a hyperosmotic shock blocks the exchange of gametic nuclei and produces self-fertilized exconjugants that are homozygous for their whole genome. Cells are sensitive to this induction during a brief period after meiosis. The high efficiency of the treatment and the fertility of the progeny make this a useful method for the isolation of induced recessive mutations and enhances the value of Tetrahymena as an animal-cell model system in which genetic dissection is practical. The sharp peak of sensitivity is useful in the study of those cellular mechanisms responsible for the independent handling of several functionally distinct nuclei during conjugation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Orias, E -- Hamilton, E P -- Flacks, M -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):660-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760210" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Nucleus/physiology ; Conjugation, Genetic ; Genes, Recessive ; Homozygote ; Mutation ; Osmotic Pressure ; Tetrahymena/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 19
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    NCI bioassays (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shubik, P -- Clayson, D B -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):746, 748.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462187" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carcinogens ; *Drug Evaluation, Preclinical ; *National Institutes of Health (U.S.) ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 20
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    NCI bioassays yield a trail of blunders (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1287-92.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451534" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay/methods ; *Carcinogens ; Legislation as Topic ; Mice ; *National Institutes of Health (U.S.) ; Research Design/standards ; Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 21
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    Government-university relations (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pings, C J -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1158.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451562" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; *Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 22
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    Surgeon general seeks physicians' help in DES alert (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Jan 12;203(4376):159.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758685" target="_blank"〉PubMed〈/a〉
    Keywords: Diethylstilbestrol/*adverse effects ; Drug Information Services ; Female ; Government Agencies ; Humans ; Mesonephroma/*chemically induced ; United States ; Vaginal Neoplasms/*chemically induced
    Print ISSN: 0036-8075
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    It could have been worse for R & D in Carter's "austerity" budget (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Feb 2;203(4379):416-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760199" target="_blank"〉PubMed〈/a〉
    Keywords: Government ; Research Support as Topic/*economics ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 24
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    Canine Babesia new to North America (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: A domestic dog residing in New England suffered a fatal febrile illness caused by a Babesia infection. The morphology of these intraerythrocytic protozoa and the range of hosts that could be infected experimentally suggested that the parasite was B. gibsoni. Although this tick-bourne disease is enzootic in wild and domestic Canidae in Africa and Asia, it appears to be new to the Americas.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, J F -- Magnarelli, L A -- Donner, C S -- Spielman, A -- Piesman, J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1431-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451574" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arthropod Vectors ; Babesia/classification/cytology ; Babesiosis/epidemiology/*parasitology/transmission ; Cricetinae ; Dog Diseases/*parasitology ; Dogs ; Erythrocytes/parasitology ; Mice ; United States
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    Jump in funding feeds research on nutrition (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1060-1, 1063-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451549" target="_blank"〉PubMed〈/a〉
    Keywords: *Diet ; Disease ; Government Agencies ; Humans ; Legislation as Topic ; *Nutritional Physiological Phenomena ; Research Support as Topic ; United States ; United States Dept. of Health and Human Services
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  • 26
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    Yearly report on carcinogens could be a potent weapon in the war on cancer (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):525-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760203" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; Dose-Response Relationship, Drug ; Government Agencies ; Humans ; Legislation, Drug ; Neoplasms/*prevention & control ; United States
    Print ISSN: 0036-8075
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  • 27
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    Radioactive waste policy is in disarray (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):312-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482940" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; Legislation as Topic ; *Radioactive Waste ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 28
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    Toxaphene, a complex mixture of polychloroterpenes and a major insecticide, is mutagenic (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: Toxaphene, the most widely used chlorinated insecticide, is mutagenic in the Salmonella test without requiring liver homogenate for activity. This insecticide is a complex mixture (more than 177 polychloroterpenes) with carcinogenic activity in rodents. Some but not all of the mutagenic components are easily separated from the insecticidal ingredients.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hooper, N K -- Ames, B N -- Saleh, M A -- Casida, J E -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):591-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377495" target="_blank"〉PubMed〈/a〉
    Keywords: Dose-Response Relationship, Drug ; Insecticides/*pharmacology ; *Mutagens ; Mutation ; Salmonella typhimurium/drug effects ; Toxaphene/*pharmacology
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  • 29
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    Public policy and health manpower (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fordham, C C 3rd -- New York, N.Y. -- Science. 1979 May 4;204(4392):459.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432650" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Medical ; Physicians/*supply & distribution ; *Public Policy ; United States ; United States Dept. of Health and Human Services
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 30
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    Normal anterior endoderm corrects the heart defect in cardiac mutant salamanders (Ambystoma mexicanum) (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: Recessive mutant gene c in axolotl embryos results in an absence of heart function. Normal (+/+) anterior endoderm cultured with mutant (c/c) hearts totally corrects the defect.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lemanski, L F -- Paulson, D J -- Hill, C S -- New York, N.Y. -- Science. 1979 May 25;204(4395):860-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441740" target="_blank"〉PubMed〈/a〉
    Keywords: Ambystoma/*embryology/genetics ; Animals ; Culture Techniques ; Embryonic Induction ; Endoderm/physiology ; Genes, Recessive ; Heart/*embryology ; Mutation ; Myocardium/ultrastructure
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    Toxic waste disposal a growing problem (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1979 May 25;204(4395):819-23.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441738" target="_blank"〉PubMed〈/a〉
    Keywords: Economics ; Environmental Pollutants/*adverse effects ; Government ; Jurisprudence ; Legislation as Topic ; *Refuse Disposal ; *Sewage ; United States ; *Waste Disposal, Fluid
    Print ISSN: 0036-8075
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  • 32
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    Albumin-deficient rat mutant (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: An analbuminemic colony was established from Sprague-Dawley rats. Analbuminemia was inherited as an autosomal recessive trait. The rates of growth and reproduction of the mutant rats were no different from those of normal rats. Biochemically, the mutant was characterized by an extraordinarily low serum albumin content and a hyperlipidemia. Total serum protein in the mutant rat was similar to that of control Sprague-Dawley rats, with increased globulin. Serum cholesterol was inversely correlated with a decrease in albumin; the correlation coefficient for ablumin was --.92. These mutant rats may serve as a model of human familial analbuminemia and may also be useful in elucidating the functional roles of albumin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nagase, S -- Shimamune, K -- Shumiya, S -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):590-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451621" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosome Aberrations/*blood ; Chromosome Disorders ; Crosses, Genetic ; Female ; Immunoelectrophoresis ; Male ; Mutation ; Rats/*genetics ; Serum Albumin/*deficiency ; Serum Globulins/analysis
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    NCI bioassay program (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Upton, A C -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):746.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462186" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carcinogens ; *Drug Evaluation, Preclinical ; *National Institutes of Health (U.S.) ; United States
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  • 34
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    Membrane potential changes during chemokinesis in Paramecium (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: Intracellular recordings show that (i) paramecia hyperpolarize slightly in attractants and depolarize in repellents that depend on the avoiding reaction (an abrupt change of swimming direction), and (ii) paramecia more strongly hyperpolarize in repellents and more strongly depolarize in attractants that depend on changes of swimming velocity. These membrane potential changes are in agreement with a hypothesis of membrane potential control of chemokinesis in Paramecium.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Van Houten, J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1100-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/572085" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal/physiology ; *Chemotaxis ; Escape Reaction/physiology ; *Membrane Potentials ; Mutation ; Paramecium/*physiology
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  • 35
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    Phenacetin studies (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vaught, J B -- King, C M -- New York, N.Y. -- Science. 1979 Nov 9;206(4419):637, 639.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493967" target="_blank"〉PubMed〈/a〉
    Keywords: Acute Kidney Injury/chemically induced ; Animals ; Biotransformation ; *Carcinogens ; Humans ; Kidney Neoplasms/chemically induced ; Mice ; Mutation ; Phenacetin/*adverse effects/metabolism
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  • 36
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    Risk and responsibility (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bazelon, D L -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):277-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451598" target="_blank"〉PubMed〈/a〉
    Keywords: Decision Making ; Government Agencies ; Jurisprudence ; *Legislation as Topic ; Legislation, Drug ; Power Plants ; *Probability ; Public Opinion ; *Risk ; *Science ; United States
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  • 37
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    Cancer and industrial chemical production (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davis, D L -- Magee, B H -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1356, 1358.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505010" target="_blank"〉PubMed〈/a〉
    Keywords: Environmental Exposure ; Humans ; *Industry ; Neoplasms/*chemically induced/epidemiology ; United States
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  • 38
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    Phenformin ban (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Finkel, M J -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):242.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432643" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Phenformin/adverse effects/*standards ; United States ; United States Food and Drug Administration
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  • 39
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    Peer review comes to ADAMHA (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1979 May 11;204(4393):601-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219482" target="_blank"〉PubMed〈/a〉
    Keywords: *Peer Review ; Research Support as Topic ; United States ; *United States Substance Abuse and Mental Health Services Administration
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  • 40
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    Scientists quit antibiotics panel at CAST (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1979 Feb 23;203(4382):732-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/581708" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed/*standards ; Anti-Bacterial Agents/*standards ; Economics ; Microbiology ; United States ; United States Food and Drug Administration
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  • 41
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    Lasker award stirs controversy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Jan 26;203(4378):341.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/216074" target="_blank"〉PubMed〈/a〉
    Keywords: *Awards and Prizes ; National Institutes of Health (U.S.) ; *Receptors, Opioid ; *Research ; United States
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  • 42
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    Hydrostatic pressure reversibly blocks membrane control of ciliary motility in Paramecium (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: A hydrostatic pressure of only 68 atmospheres prevented swimming Paramecium caudatum from "avoiding" or reversing direction; 170 atmospheres stopped or decreased forward velocity by more than 75 percent. A decompression of 40 atmospheres invoked a single reversal, even at ,80 atmospheres. In contrast, 170 atmospheres did not significantly affect swimming behavior of paramecium "models" that were reactivated in a solution containing adenosine triphosphate and magnesium ions after their membrane had been disrupted by Triton X-100.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Otter, T -- Salmon, E D -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):358-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482945" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Membrane/physiology ; Cilia/physiology ; Hydrostatic Pressure ; Ion Channels/physiology ; Membrane Potentials ; Movement ; Mutation ; Paramecium/genetics/*physiology ; Polyethylene Glycols/pharmacology
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  • 43
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    Air is once again rent by drug lag claims (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):283.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451599" target="_blank"〉PubMed〈/a〉
    Keywords: *Drug Evaluation ; Legislation, Drug ; Time Factors ; United States ; *United States Food and Drug Administration
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  • 44
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    Toxic substances: EPA and OSHA are reluctant regulators (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):28-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758675" target="_blank"〉PubMed〈/a〉
    Keywords: Cadmium/standards/toxicity ; Carcinogens/standards ; *Environmental Health ; *Government Agencies ; Humans ; Occupational Medicine/*standards ; Pesticides/toxicity ; United States
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  • 45
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    Study finds sleeping pills overprescribed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):287-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219479" target="_blank"〉PubMed〈/a〉
    Keywords: Barbiturates/adverse effects/pharmacology ; Benzodiazepines/adverse effects/metabolism ; Humans ; Hypnotics and Sedatives/*adverse effects ; Metabolic Clearance Rate ; Sleep, REM/drug effects ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Carter attempt to limit doctor supply faces tough going in Congress (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):630-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760209" target="_blank"〉PubMed〈/a〉
    Keywords: Cost Control ; Delivery of Health Care/*economics ; Education, Medical/*manpower ; Legislation as Topic ; Physicians/*supply & distribution ; Training Support/*economics ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 47
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    Federal government faces painful decision on Darvon (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 2;203(4383):857-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/419410" target="_blank"〉PubMed〈/a〉
    Keywords: Dextropropoxyphene/*adverse effects/therapeutic use ; Humans ; *Legislation, Drug ; Substance-Related Disorders ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 48
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    Federal research grants (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Staats, E B -- New York, N.Y. -- Science. 1979 Jul 6;205(4401):18-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451578" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; *Research Support as Topic ; United States ; Universities
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 49
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    Diabetes drugs: clinical trial (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prout, T E -- Knatterud, G L -- Meinert, C G -- New York, N.Y. -- Science. 1979 Apr 27;204(4391):362-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/375390" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic ; Control Groups ; Diabetes Mellitus/*drug therapy ; Drug Evaluation/methods ; Drug Therapy ; Humans ; Hypoglycemic Agents/*toxicity ; Risk Assessment ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 50
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    Margaret Mead: an American phenomenon, 1901--1978 (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Revelle, R -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):39-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/364654" target="_blank"〉PubMed〈/a〉
    Keywords: Anthropology, Cultural/*history ; History, 20th Century ; Societies, Scientific/history ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 51
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    Siamese cat: altered connections of visual cortex (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: In siamese cats, each side of the brain receives a retinal input serving part of the ipsilateral visual field as well as the normal contralateral field representation. Both corticothalamic and cortico-cortical projections are systematically rearranged, but while one is retinotopically appropriate, the other fails to make a distinction between ipsilateral and contralateral fields. Different rules appear to govern the development of these two sets of connections.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shatz, C J -- LeVay, S -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):328-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432647" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain Mapping ; Cats/*anatomy & histology/growth & development ; Functional Laterality ; Geniculate Bodies/anatomy & histology ; Mutation ; Retina/*anatomy & histology ; Visual Cortex/*anatomy & histology ; Visual Pathways/anatomy & histology/growth & development
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 52
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    Spectacular science and ponderous process (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Singer, M F -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758684" target="_blank"〉PubMed〈/a〉
    Keywords: *Advisory Committees ; DNA, Recombinant/*standards ; Federal Government ; *Government Regulation ; Research Design/standards ; Safety ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 53
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    EPA halts most use of herbicide 2,4,5-T (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, J -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1090-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424734" target="_blank"〉PubMed〈/a〉
    Keywords: 2,4,5-Trichlorophenoxyacetic Acid/adverse effects/*standards ; Abortion, Spontaneous/*chemically induced ; Female ; Government Agencies ; Humans ; Legislation, Drug ; Pregnancy ; Tetrachlorodibenzodioxin/toxicity ; United States
    Print ISSN: 0036-8075
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  • 54
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    Cancer policy announced (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):313.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482941" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; Government Agencies ; Risk ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 55
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    Jere Goyan brings innovative record to FDA (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Oct 12;206(4415):200-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482934" target="_blank"〉PubMed〈/a〉
    Keywords: Pharmacy/standards ; United States ; *United States Food and Drug Administration/organization & administration
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 56
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    U.S. beginning to act on banned pesticides (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1391-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451572" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Developing Countries ; Humans ; Legislation as Topic ; *Pesticides/poisoning ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 57
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    Henry Waxman still faces an uphill battle (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 30;203(4387):1319, 1321-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/370981" target="_blank"〉PubMed〈/a〉
    Keywords: California ; History of Medicine ; *Legislation as Topic ; Politics ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 58
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    Institute of Medicine report recommends complete overhaul of food safety laws (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 23;203(4386):1221-2, 1224.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424748" target="_blank"〉PubMed〈/a〉
    Keywords: Carcinogens ; Dose-Response Relationship, Drug ; Food Additives/*standards ; Saccharin ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 59
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    Major relaxation in DNA rules (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1238.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472740" target="_blank"〉PubMed〈/a〉
    Keywords: *DNA, Recombinant ; National Institutes of Health (U.S.) ; Research Design/standards ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 60
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    Proposals for ethics boards stir debate (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):285-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451600" target="_blank"〉PubMed〈/a〉
    Keywords: Compensation and Redress ; *Ethics Committees, Research ; Ethics, Medical ; Federal Government ; Government Regulation ; *Human Experimentation ; Humans ; *Informed Consent ; *Professional Staff Committees/legislation & jurisprudence ; Risk ; United States
    Print ISSN: 0036-8075
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  • 61
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    Paul Feyerabend: science and the anarchist (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):534-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/386510" target="_blank"〉PubMed〈/a〉
    Keywords: History, 20th Century ; Logic ; *Philosophy ; Science/history ; United States
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  • 62
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    Dollars for drug research flow overseas (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):979-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472730" target="_blank"〉PubMed〈/a〉
    Keywords: Drug Evaluation/methods ; Drug Evaluation, Preclinical/methods ; *Drug Industry ; Economics ; Federal Government ; Government Regulation ; *Internationality ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
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    How to assess cancer risks (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 May 25;204(4395):811, 813, 815-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441737" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Government Agencies ; Humans ; Mice ; Neoplasms/*chemically induced ; Rats ; Risk ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 64
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    A new and searching look at NSF (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1064-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451550" target="_blank"〉PubMed〈/a〉
    Keywords: *Government Agencies ; Legislation as Topic ; Research Support as Topic ; *Science ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 65
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    Should there be a commission on medical education? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: In its premedical and preclinical phases our present scheme of education for medicine is intellectually deficient, wasteful of money and time, and in urgent need of overhaul. The author defines conditions under which a national commission might possibly set the educational process on the road to reform.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chapman, C B -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):559-62.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451620" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Medical/*standards ; *Professional Staff Committees ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    FDA tells senators of doctors who fake data in clinical drug trials (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):423-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504984" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic/*standards ; Drug Industry/standards ; Legislation as Topic ; United States ; United States Food and Drug Administration
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 67
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    Differential mortality by sex in fetal and neonatal deaths (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: Vital statistics data for the United States from 1922 to 1936 and from 1950 to 1972 were used to analyze fetal and early neonatal mortality. This analysis corroborates the previously established pattern of the sex ratio of fetal deaths--highest from months 3 to 5, lower from months 6 to 7 or 8, and increasing at term. It also indicates a postponement of late fetal deaths into the early infant period. Whereas earlier research reports have described the pattern of the sex ratio of fetal deaths, this report repeats this analysis for a recent national data base. This line of analysis is extended by using the patterns observed in the data to produce an empirical estimate of the primary sex ratio. For 1950 to 1972, this ratio (male to female) is conservatively estimated to be 120:100.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McMillen, M M -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):89-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/571144" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Fetal Death/*epidemiology ; Humans ; *Infant Mortality ; Male ; Pregnancy ; *Sex Ratio ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 68
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    OSHA carcinogen policy delayed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, J R -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):35.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758676" target="_blank"〉PubMed〈/a〉
    Keywords: Carcinogens/standards ; *Government Agencies ; Laboratories/standards ; Occupational Medicine/*standards ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 69
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    Court reluctantly upholds EPA on 2,4,5-T suspension (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 May 11;204(4393):602.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432664" target="_blank"〉PubMed〈/a〉
    Keywords: 2,4,5-Trichlorophenoxyacetic Acid/*standards ; *Government Agencies ; Jurisprudence ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Joint statement issued by CDC, HEW, NIEHS (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):282.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/221981" target="_blank"〉PubMed〈/a〉
    Keywords: *Cannabis ; Centers for Disease Control and Prevention (U.S.) ; Humans ; National Institutes of Health (U.S.) ; Paraquat/*poisoning ; United States ; United States Dept. of Health and Human Services
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  • 71
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    Water, protein folding, and the genetic code (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: The absolute affinities of amino acid side chains for solvent water closely match their relative distributions between the surface and the interior of native proteins and are associated with a remarkable bias in the genetic code.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wolfenden, R V -- Cullis, P M -- Southgate, C C -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):575-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493962" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acids/*genetics ; *Genetic Code ; Mutation ; Protein Conformation ; Solubility ; Thermodynamics ; Water
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 72
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    Regulators defend their turf (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1978 Nov 10;202(4368):603.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705348" target="_blank"〉PubMed〈/a〉
    Keywords: Economics ; *Environmental Health ; Government Agencies ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 73
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    Uranium mill tailings: Congress addresses a long-neglected problem (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):191-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694524" target="_blank"〉PubMed〈/a〉
    Keywords: *Environmental Exposure ; Legislation as Topic ; Mining/*standards ; New Mexico ; United States ; *Uranium ; Utah
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 74
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    Changing postdoctoral career patterns for biomedical scientists (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-03
    Description: Between 1973 and 1977 the total number of Ph.D.'s holding postdoctoral appointments in the biomedical sciences increased at a rate of more than 550 individuals (12.5 percent) per year. During this same period the total number of doctorates awarded each year in these disciplines showed very little change. The postdoctoral growth can be attributed to substantial increases in both the numbers of recent graduates taking postdoctorals and the length of stay on these appointments. The lack of alternative employment opportunities has contributed heavily to the postdoctoral buildup. Continued growth is likely to have important consequences for biomedical research and research training.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coggeshall, P E -- Norvell, J C -- Bogorad, L -- Bock, R M -- New York, N.Y. -- Science. 1978 Nov 3;202(4367):487-93.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705338" target="_blank"〉PubMed〈/a〉
    Keywords: Biology/*manpower/trends ; Education, Continuing/*trends ; Employment ; *Research Support as Topic ; Salaries and Fringe Benefits ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 75
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    Health care economics: the high cost of getting well (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Culliton, B J -- New York, N.Y. -- Science. 1978 May 26;200(4344):883-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/644330" target="_blank"〉PubMed〈/a〉
    Keywords: Bed Occupancy ; Diagnosis/economics ; Economics, Hospital ; *Economics, Medical ; Education, Medical ; Fees and Charges ; Insurance, Health/economics ; Legislation, Medical ; Medical Laboratory Science/economics ; Therapeutics/economics ; United States
    Print ISSN: 0036-8075
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  • 76
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    The quality of medical care (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: This article classifies the major approaches to the assessment of the process and outcomes of medical care. The apparent need to safeguard and enhance the quality of care has led to the institution of mechanisms that subject care to constant review so that deficiencies may be found and corrected. The article reviews the developments that led to the involvement of the federal government in this activity through its sponsorship of professional standards review organizations (PSRO's). The major features of the PSRO's are described and their possible effects discussed. It is too early to say how the PSRO's will fare, but should they fail to accomplish their objectives the pressure for more radical solutions will be difficult to resist.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Donabedian, A -- New York, N.Y. -- Science. 1978 May 26;200(4344):856-64.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417400" target="_blank"〉PubMed〈/a〉
    Keywords: Computers ; Concurrent Review ; Cost-Benefit Analysis ; Humans ; Medical Records/standards ; Methods ; Peer Review ; Physician-Patient Relations ; Professional Review Organizations/economics/legislation & jurisprudence/standards ; *Quality of Health Care ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 77
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    Malignant neoplasms of genetic origin in Drosophila melanogaster (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-30
    Description: Malignant neoplasms that develop in 12 recessive-lethal, larval mutants of Drosophila melanogaster are discussed. These mutations affect the adult optic neuroblasts and ganglion-mother cells in the larval brain, the imaginal discs, and the hematopoietic organs. The malignant neoplasms exhibit fast, autonomous growth, loss of the capacity for differentiation, increased mobility and invasiveness, lethality in situ and after transplantation, and histological, fine structural, and karyotypic abnormalities. Intermediate neoplasms are also found. These combine both benign and malignant qualities. They grow in a noninvasive, compact fashion, typical of benign tumors, yet they also exhibit malignant qualities such as fast, autonomous, and lethal growth, loss of differentiation capacity, changes in cellular morphology, and lethal growth after transplantation into wild-type hosts. Thus Drosophila and vertebrate neoplasms show striking similarities.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gateff, E -- New York, N.Y. -- Science. 1978 Jun 30;200(4349):1448-59.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/96525" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Cells/pathology ; *Cell Transformation, Neoplastic ; Drosophila melanogaster/*genetics/growth & development ; Ecdysone/pharmacology ; Hematopoiesis ; Mutation ; Neoplasm Transplantation ; Neoplasms, Experimental/*genetics/pathology ; Neuroblastoma/genetics/pathology
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 78
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    How valuable are scientific exchanges with the Soviet Union? (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Graham, L R -- New York, N.Y. -- Science. 1978 Oct 27;202(4366):383-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705332" target="_blank"〉PubMed〈/a〉
    Keywords: *Foreign Professional Personnel ; *International Cooperation ; *Science ; Ussr ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 79
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    Research involving human subjects (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-22
    Description: This article reports a study of the activities and performance of institutional review boards to protect human research subjects. Researchers and institutional review board members were generally supportive of the review system, although substantial criticisms were also heard. Institutional review boards had some direct impact on half of the proposals reviewed by requiring either modification of or additional information about proposed research. The data, however, raise questions about the effectiveness of some review board actions, for example, with regard to informed consent. Some policy implications of the study are presented.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gray, B H -- Cooke, R A -- Tannenbaum, A S -- New York, N.Y. -- Science. 1978 Sep 22;201(4361):1094-101.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/356268" target="_blank"〉PubMed〈/a〉
    Keywords: Attitude ; Behavioral Research ; Bioethics ; Clinical Trials as Topic ; Consent Forms ; *Ethical Review ; *Ethics Committees, Research ; *Human Experimentation ; Humans ; Informed Consent ; *Research/standards ; Risk ; Risk Assessment ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 80
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    alpha1-Antitrypsin: the presence of excess mannose in the Z variant isolated from liver (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-29
    Description: The Z variant of alpha1-antitrypsin was isolated by a new technique from the liver of a patient homozygous for the Z allele of the protease inhibitor locus. The material was homogenous and antigenically competent but had no protease inhibiting capacity. An interesting correlation was found between the subcellular localization and the carbohydrate composition of the Z variant from liver. Carbohydate analysis of this glycoprotein showed an absence of galactose and sialic acid, an appreciable decrease in N-acetylglucosamine, and an almost twofold increase in mannose residues. These data indicate a considerable slowdown in the processing of the oligosaccharides of liver Z variant. In spite of the absence of sialyl residues, the liver Z varant was microheterogeneous by analytical isoelectric focusing. The isoproteins of liver Z variant coincided with those of asialo M variant in the focusing field.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hercz, A -- Katona, E -- Cutz, E -- Wilson, J R -- Barton, M -- New York, N.Y. -- Science. 1978 Sep 29;201(4362):1229-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/308696" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Carbohydrate Metabolism ; Female ; Galactose/metabolism ; Glycoproteins/genetics ; Homozygote ; Humans ; Liver/metabolism ; Mannose/metabolism ; Middle Aged ; Mutation ; Phenotype ; Sialic Acids/metabolism ; alpha 1-Antitrypsin/*genetics/metabolism
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  • 81
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    Upton OK's Laetrile test on humans (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):196.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694525" target="_blank"〉PubMed〈/a〉
    Keywords: Amygdalin/*therapeutic use ; Federal Government ; Humans ; National Institutes of Health (U.S.) ; Neoplasms/*drug therapy ; Research Support as Topic ; United States
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  • 82
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    Care of the aged: old problems in need of new solutions (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: Long-term care for the aged in the United States is overly dependent upon the nursing home. This hospital-like model for long-term care is particularly inappropriate since it imposes a medical solution on a variety of social problems. An adequate long-term care program requires a range of resources in the community as well as in institutions; sheltered housing options seem a desirable alternative to the nursing home. To ensure the quality of nursing home care, the present focus on setting standards for care activities should be abandoned in favor of a focus on care outcomes (physical, mental, and social). In an effort to change our present perverse incentives in the nursing home industry, the proposal is made that nursing homes be reimbursed according to the degree to which patient outcomes meet predicted outcomes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kane, R L -- Kane, R A -- New York, N.Y. -- Science. 1978 May 26;200(4344):913-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417403" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Financing, Government ; Health Facilities, Proprietary ; *Homes for the Aged/economics ; Humans ; Long-Term Care/*methods ; *Nursing Homes/economics/standards ; Socioeconomic Factors ; United States
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  • 83
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    Environmental groups lose friends in effort to control DNA research (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1978 Dec 22;202(4374):1265-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/725600" target="_blank"〉PubMed〈/a〉
    Keywords: DNA, Recombinant/*standards ; Environment ; Environmental Pollution/prevention & control ; Government Regulation ; Legislation as Topic ; Research Design/*standards ; Risk Assessment ; United States
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  • 84
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    EPA smog standard attacked by industry, science advisers (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1978 Dec 1;202(4371):949-50.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715452" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants/toxicity ; Dose-Response Relationship, Drug ; Environmental Exposure ; Government Agencies ; Humans ; Industry ; Ozone/toxicity ; United States
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  • 85
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    Health officials fired up over "tolerable" cigarettes (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1978 Sep 1;201(4358):795-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/684406" target="_blank"〉PubMed〈/a〉
    Keywords: National Institutes of Health (U.S.) ; Nicotine/toxicity ; Smoking/*complications ; Tars/toxicity ; United States ; United States Dept. of Health and Human Services
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  • 86
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    Federal health spending passes the $50-billion mark (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walsh, J -- New York, N.Y. -- Science. 1978 May 26;200(4344):886-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/347578" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Medical ; *Financing, Government ; Health Services/*economics ; Legislation, Medical ; Medicaid/economics ; Medicare/economics ; Professional Review Organizations/economics ; Research Support as Topic ; Training Support ; United States
    Print ISSN: 0036-8075
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  • 87
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    New rulebook for gene splicers faces one more test (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1978 Aug 18;201(4356):600-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/353985" target="_blank"〉PubMed〈/a〉
    Keywords: DNA, Recombinant/*standards ; DNA, Viral/genetics ; Escherichia coli/genetics/pathogenicity ; *Federal Government ; *Government Regulation ; National Institutes of Health (U.S.) ; Research Design/standards ; Risk Assessment ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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  • 88
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    Biological warfare fears may impede last goal of smallpox eradicators (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1978 Jul 28;201(4353):329-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/208151" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Warfare ; Centers for Disease Control and Prevention (U.S.) ; *Smallpox/prevention & control ; United States ; Variola virus ; Virus Cultivation ; *World Health Organization
    Print ISSN: 0036-8075
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  • 89
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    Policy recommendations to VA leave NAS at odds with Congress (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walsh, J -- New York, N.Y. -- Science. 1978 Mar 3;199(4332):952-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/341315" target="_blank"〉PubMed〈/a〉
    Keywords: *Academies and Institutes ; *Delivery of Health Care ; *Public Policy ; United States ; *United States Department of Veterans Affairs
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 90
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    The problem of defensive medicine (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: Defensive medicine--the use of diagnostic and end-treatment measures explicitly for the purposes of averting malpractice suits--is frequently cited as one of the least desirable effects of the current rise in medical litigation. Many physicians and policy-makers claim that defensive medicine is responsible not only for the increasing costs of health care but the exposing of patients to significant risks of harm from unnecessary procedures. Very little solid information is available about defensive medicine. The studies that have been conducted have been fraught with statistical difficulties and are by no means definitive. Even more important than the issue of defensive medicine is the more basic problem of our system of compensation for medical injuries.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tancredi, L R -- Barondess, J A -- New York, N.Y. -- Science. 1978 May 26;200(4344):879-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/644329" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Cesarean Section/utilization ; Child ; Costs and Cost Analysis ; Craniocerebral Trauma/radiography ; *Defensive Medicine/economics ; Female ; Fetal Monitoring/utilization ; Humans ; *Malpractice/economics ; Physician-Patient Relations ; Pregnancy ; Quality of Health Care ; Surveys and Questionnaires ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 91
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    Carbon monoxide automobile emissions measured from the interior of a traveling automobile (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-17
    Description: During a procedure to monitor carbon monoxide (CO) concentrations inside a traveling car, it was discovered that CO emissions from individual passing vehicles produced accurately measurable increases in the CO concentration. The CO produced by individual vehicles varied by three orders of magnitude; this finding demonstrates that a relatively small number of cars can be responsible for a high percentage of total vehicle CO Emissions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chaney, L W -- New York, N.Y. -- Science. 1978 Mar 17;199(4334):1203-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/75569" target="_blank"〉PubMed〈/a〉
    Keywords: Automobile Driving ; Automobiles/standards ; Carbon Monoxide/*analysis ; Environment ; Rural Population ; United States ; Urban Population ; Vehicle Emissions/*analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 92
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    Doctors and their autonomy: past events and future prospects (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chapman, C B -- New York, N.Y. -- Science. 1978 May 26;200(4344):851-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/347577" target="_blank"〉PubMed〈/a〉
    Keywords: Economics, Medical ; Great Britain ; History, 16th Century ; History, 17th Century ; History, 19th Century ; History, 20th Century ; History, Medieval ; Legislation, Medical/history ; Licensure, Medical/history ; *Malpractice/history ; *Peer Review ; *Physicians ; Quality of Health Care ; Societies, Medical/history ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 93
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    Research in instrument sharing (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-04
    Description: Continued progress in many areas of science depends on access to advanced modern instruments and the data they provide. Costly instruments have been shared in a number of disciplines for many years, and common patterns of shared usage have developed independently. The scientific and financial aspects of large instrument usage are discussed from the points of view of the instrument centers, the users, and the funding agencies. The instrument problem is not one problem but many, and coordinated solutions must be implemented with well-defined goals based on knowledge of the needs of the users and developers of instruments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coulter, C L -- New York, N.Y. -- Science. 1978 Aug 4;201(4354):415-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663665" target="_blank"〉PubMed〈/a〉
    Keywords: Biophysics/instrumentation ; Cell Biology/instrumentation ; Chemistry/instrumentation ; Computers/supply & distribution ; *Equipment and Supplies ; Government Agencies ; Microscopy, Electron/instrumentation ; Molecular Biology/instrumentation ; Particle Accelerators/supply & distribution ; *Research ; Research Support as Topic ; Spectrum Analysis/instrumentation ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 94
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    Ethics advisory board confronts conception in the test tube (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Culliton, B J -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):198-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/567844" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Research ; *Ethics, Medical ; Federal Government ; Female ; *Fertilization in Vitro ; Government Regulation ; Humans ; In Vitro Techniques ; Infertility/therapy ; Male ; National Institutes of Health (U.S.) ; Research Support as Topic ; Risk Assessment ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 95
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    Toxic substances legislation: how well are laws being implemented? (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Culliton, B J -- New York, N.Y. -- Science. 1978 Sep 29;201(4362):1198-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694509" target="_blank"〉PubMed〈/a〉
    Keywords: Carcinogens, Environmental ; *Environmental Pollutants ; Environmental Pollution/*prevention & control ; Government Agencies ; *Legislation as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 96
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    Information transfer: the biomedical model (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cummings, M M -- New York, N.Y. -- Science. 1978 Dec 22;202(4374):1247.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/364650" target="_blank"〉PubMed〈/a〉
    Keywords: *Information Systems ; *Medlars ; National Library of Medicine (U.S.) ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 97
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    Peter Bourne's mistake: a prescription for trouble (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Culliton, B J -- New York, N.Y. -- Science. 1978 Aug 4;201(4354):421-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/351809" target="_blank"〉PubMed〈/a〉
    Keywords: Drug Prescriptions/*standards ; *Ethics, Pharmacy ; Government Agencies ; History, 20th Century ; Methaqualone/administration & dosage ; Psychiatry/history ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 98
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    Cancer death risk in hospitalized mental patients (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fox, B H -- New York, N.Y. -- Science. 1978 Sep 15;201(4360):966-968.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/684429" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Female ; Hospitalization ; Humans ; Male ; Mental Disorders/*complications ; Middle Aged ; Neoplasms/*mortality ; Risk ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 99
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    Stimulated DNA synthesis in frog nuclei by cytoplasmic extracts of temperature-sensitive mammalian cells (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-18
    Description: Cytoplasmic extracts of proliferating cells stimulate DNA synthesis in isolated nuclei of Xenopus laevis liver. When tested by the same assay, cytoplasmic extracts of resting cells are completely inactive. When cytoplasmic extracts are prepared from cell cycle-specific temperature-sensitive mutants arrestd in the G1 phase of the cell cycle by the nonpermissive temperature, they also fail to stimulate DNA synthesis in frog nuclei. The results indicate that, to stimulate DNA synthesis in isolated frog nuclei, essentially all information of G1 cells must be present.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Floros, J -- Chang, H -- Baserga, R -- New York, N.Y. -- Science. 1978 Aug 18;201(4356):651-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/675253" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Cycle ; Cell Line ; Cell Nucleus/*metabolism ; Chickens ; Cytoplasm/physiology ; DNA/*biosynthesis ; Liver/ultrastructure ; Mutation ; Temperature ; Xenopus
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 100
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    Evaluation of medical practices (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: Evaluation of the efficacy of a medical intervention requires valid measurements of both its benefits and risks as compared to those of alternative forms of management. The requisite measurements are more difficult to make than this simple description suggests, and the accumulation of information is further inhibited by certain characteristics of our pattern of health care. These features include, for example, discontinuous care by a variety of unrelated providers, inadequate records, the autonomy of physicians as decision-makers, financial disincentives, ambiguities in what we mean by "experimental" and "accepted" forms of therapy, and failure to see continuing evaluation as a necessary component of the cost of providing good medical care. Although no single change will solve all the problems of evaluation, several offer promise of improving our ability to choose from among medical interventions those most likely to be useful.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Frazier, H S -- Hiatt, H H -- New York, N.Y. -- Science. 1978 May 26;200(4344):875-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417402" target="_blank"〉PubMed〈/a〉
    Keywords: Cost-Benefit Analysis ; Defensive Medicine ; Delivery of Health Care/organization & administration ; Diagnostic Errors ; Ethics, Medical ; Humans ; Malpractice ; Medical Records ; *Quality of Health Care/economics ; Quality of Life ; Risk ; Therapeutics ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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